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Index > Protein center > SIM1(Gene name) > Human
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  • SIM1 (Gene name),
  • Single-minded homolog 1 (Protein name ),  SIM1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    SIM1(BHLHE14);
    Protein name:
    Single-minded homolog 1;
    Alternative:
    Class E basic helix-loop-helix protein 14(bHLHe14);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Efficient DNA binding requires dimerization with another bHLH protein. Heterodimer of SIM1 and ARNT.
    Function:
    Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    766
    Sequence:
    50:
    MKEKSKNAAR | TRREKENSEF | YELAKLLPLP | SAITSQLDKA | SIIRLTTSYL | 
    100:
    KMRVVFPEGL | GEAWGHSSRT | SPLDNVGREL | GSHLLQTLDG | FIFVVAPDGK | 
    150:
    IMYISETASV | HLGLSQVELT | GNSIYEYIHP | ADHDEMTAVL | TAHQPYHSHF | 
    200:
    VQEYEIERSF | FLRMKCVLAK | RNAGLTCGGY | KVIHCSGYLK | IRQYSLDMSP | 
    250:
    FDGCYQNVGL | VAVGHSLPPS | AVTEIKLHSN | MFMFRASLDM | KLIFLDSRVA | 
    300:
    ELTGYEPQDL | IEKTLYHHVH | GCDTFHLRCA | HHLLLVKGQV | TTKYYRFLAK | 
    350:
    HGGWVWVQSY | ATIVHNSRSS | RPHCIVSVNY | VLTDTEYKGL | QLSLDQISAS | 
    400:
    KPAFSYTSSS | TPTMTDNRKG | AKSRLSSSKS | KSRTSPYPQY | SGFHTERSES | 
    450:
    DHDSQWGGSP | LTDTASPQLL | DPADRPGSQH | DASCAYRQFS | DRSSLCYGFA | 
    500:
    LDHSRLVEER | HFHTQACEGG | RCEAGRYFLG | TPQAGREPWW | GSRAALPLTK | 
    550:
    ASPESREAYE | NSMPHIASVH | RIHGRGHWDE | DSVVSSPDPG | SASESGDRYR | 
    600:
    TEQYQSSPHE | PSKIETLIRA | TQQMIKEEEN | RLQLRKAPSD | QLASINGAGK | 
    650:
    KHSLCFANYQ | QPPPTGEVCH | GSALANTSPC | DHIQQREGKM | LSPHENDYDN | 
    700:
    SPTALSRISS | PNSDRISKSS | LILAKDYLHS | DISPHQTAGD | HPTVSPNCFG | 
    750:
    SHRQYFDKHA | YTLTGYALEH | LYDSETIRNY | SLGCNGSHFD | VTSHLRMQPD | 
    766:
    PAQGHKGTSV | IITNGS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    SMR:
    String:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Single-minded homolog 1
    ELISA Kit for Human Single-minded homolog 1
    CLIA Kit for Human Single-minded homolog 1
    CLIA Kit for Human Single-minded homolog 1
    Polyclonal Antibody for Human Single-minded homolog 1
    Polyclonal Antibody for Human Single-minded homolog 1
    Monoclonal Antibody for Human Single-minded homolog 1
    Monoclonal Antibody for Human Single-minded homolog 1
    Protein for Human Single-minded homolog 1
    Protein for Human Single-minded homolog 1

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Cloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region."
      Chrast R. , Scott H.S. , Chen H. , Kudoh J. , Rossier C. , Minoshima S. , Wang Y. , Shimizu N. , Antonarakis S.E.
      Genome Res.7:615-624(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "A novel nuclear localization signal in the human single-minded proteins SIM1 and SIM2."
      Yamaki A. , Kudoh J. , Shimizu N. , Shimizu Y.
      Biochem. Biophys. Res. Commun.313:482-488(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;NUCLEAR LOCALIZATION SIGNAL
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