Sit1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comSit1 ELISA Kit for Rat(Rattus norvegicus)

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Sit1 (Gene name),

Signaling threshold-regulating transmembrane adapter 1 (Protein name ), SIT1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Sit1(Sit);

Protein name:

Signaling threshold-regulating transmembrane adapter 1;

Alternative:

Suppression-inducing transmembrane adapter 1;SHP2-interacting transmembrane adapter protein;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homodimer; disulfide-linked. When phosphorylated, interacts with PTPN11/SHP2, GRB2 and CSK.

Function:

Negatively regulates T-cell antigen receptor (TCR)-mediated signaling. Involved in positive selection of T-cells.

Subcellular Location:

Cell membrane Single-pass type III membrane protein

Protein Attributes:

Sequence length:

178

Sequence:

50:

100:

150:

178:

YASVCAQTRR | ARASFPDQAY | ANSQPAPS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.47894

STRING:

10116.ENSRNOP00000036171

KEGG:

rno:500449

Uniprot:

Q5M869

FOR

ELISA Kit for Rat Signaling threshold-regulating transmembrane adapter 1

CLIA Kit for Rat Signaling threshold-regulating transmembrane adapter 1

Polyclonal Antibody for Rat Signaling threshold-regulating transmembrane adapter 1

Monoclonal Antibody for Rat Signaling threshold-regulating transmembrane adapter 1

Protein for Rat Signaling threshold-regulating transmembrane adapter 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Spleen.
2.

"Transmembrane adaptor molecules: a new category of lymphoid-cell markers."
Tedoldi S. , Paterson J.C. , Hansmann M.-L. , Natkunam Y. , Rudiger T. , Angelisova P. , Du M.Q. , Roberton H. , Roncador G. , Sanchez L. , Pozzobon M. , Masir N. , Barry R. , Pileri S. , Mason D.Y. , Marafioti T. , Horejsi V.
Blood107:213-221(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY

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