Protein name:
Spindle and kinetochore-associated protein 3 ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Component of the SKA1 complex, composed of SKA1, SKA2 and SKA3. The core SKA1 complex is composed of 2 SKA1-SKA2 heterodimers, each heterodimer interacting with a molecule of the SKA3 homodimer. The core SKA1 complex associates with microtubules and forms oligomeric assemblies. Interacts directly with SKA1.
Function:
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization.
Subcellular Location:
Cytoplasm
cytoskeleton
spindle
Chromosome
centromere
kinetochore
Localizes to the outer kinetochore and spindle microtubules during mitosis in a NDC80 complex-dependent manner.
Protein Attributes:
50:
MDPIRGFCGK | LRSLAVTLDS | ETARLQRALD | GEDSDFEDCP | MRVLHDLNSE |
100:
VRILKDDVNI | LLDKANLESQ | ENIGFIKATK | ILMRKNSMDI | MKIKEFFQKY |
150:
GYTPRAKKNS | VDEQEVTDSK | PESSECERPE | KPDLKDDLLD | SAAASTSVSE |
200:
KSPRSPQLSD | FGLERYIVSQ | VLPNPPQAVN | NQKEEPKILT | PFSKHSLLKT |
250:
PKCALKMDDF | ECVTPKLEHF | GISEYTMCLN | DDYTIGLKNV | KTNSETIETE |
300:
PVPNDNVFAT | PGLITQPLGK | NNAEHTHSPL | APTFCTPGLK | VPSTKTSTAM |
350:
VSTNSSSNDL | ETKESTSLVS | NSDECFENFA | DPSSPTISSY | ENLLKTPTPP |
400:
EVTTIPEDIR | QILSKYNSNL | ASPVAVRAVS | PINVFLPRHG | GQNMRDASNK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Mouse
Rat
ELISA Kit for Bovine Spindle and kinetochore-associated protein 3
ELISA Kit for Bovine Spindle and kinetochore-associated protein 3
ELISA Kit for Bovine Spindle and kinetochore-associated protein 3
ELISA Kit for Bovine Spindle and kinetochore-associated protein 3
CLIA Kit for Bovine Spindle and kinetochore-associated protein 3
CLIA Kit for Bovine Spindle and kinetochore-associated protein 3
CLIA Kit for Bovine Spindle and kinetochore-associated protein 3
CLIA Kit for Bovine Spindle and kinetochore-associated protein 3
Polyclonal Antibody for Bovine Spindle and kinetochore-associated protein 3
Polyclonal Antibody for Bovine Spindle and kinetochore-associated protein 3
Polyclonal Antibody for Bovine Spindle and kinetochore-associated protein 3
Polyclonal Antibody for Bovine Spindle and kinetochore-associated protein 3
Monoclonal Antibody for Bovine Spindle and kinetochore-associated protein 3
Monoclonal Antibody for Bovine Spindle and kinetochore-associated protein 3
Monoclonal Antibody for Bovine Spindle and kinetochore-associated protein 3
Monoclonal Antibody for Bovine Spindle and kinetochore-associated protein 3
Protein for Bovine Spindle and kinetochore-associated protein 3
Protein for Bovine Spindle and kinetochore-associated protein 3
Protein for Bovine Spindle and kinetochore-associated protein 3
Protein for Bovine Spindle and kinetochore-associated protein 3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
strain :
Hereford .
tissue :
Testis .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 177-403 (ISOFORM 1)