Sla ELISA Kit for Rat(Rattus norvegicus) | EIAab.comSla ELISA Kit for Rat(Rattus norvegicus)

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Sla (Gene name),

Src-like-adapter (Protein name ), SLAP1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Sla(Slap;Slap1);

Protein name:

Src-like-adapter;

Alternative:

Src-like-adapter protein 1(SLAP-1);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homodimer. Interacts with phosphorylated CBL, SYK and LAT. Homodimerization and interaction with phosphorylated CBL occurs via its C-terminal domain. Interacts with PDGFRB and EPHA2. Interacts with phosphorylated proteins ZAP70; CD3Z; VAV1 and LCP2 via its SH2 domain.

Function:

Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.

Subcellular Location:

Cytoplasm Endosome Colocalizes with endosomes.

Protein Attributes:

Sequence length:

312

Sequence:

50:

100:

150:

200:

250:

300:

312:

AGTQKTKALT | AT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.35223

KEGG:

rno:338477

SMR:

P59622

Pfam:

PF00017

STRING:

10116.ENSRNOP00000007982

String:

P59622

Uniprot:

P59622

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ELISA Kit for Rat Src-like-adapter

CLIA Kit for Rat Src-like-adapter

Polyclonal Antibody for Rat Src-like-adapter

Monoclonal Antibody for Rat Src-like-adapter

Protein for Rat Src-like-adapter

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

Alifragis P. , Molnar Z. , Parnavelas J.
Submitted (2003-01) to the EMBL/GenBank/DDBJ databases

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