Slit1 ELISA Kit for Mouse(Mus musculus) | EIAab.comSlit1 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Slit1(Gene name) > Mouse

Slit1 (Gene name),

Slit homolog 1 protein (Protein name ), SLIT1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Slit1(Kiaa0813);

Protein name:

Slit homolog 1 protein(Slit-1);

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with GREM1 (By similarity) and ROBO1.

Function:

Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

1531

Sequence:

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1531:

KRRKLTFECS | DGTSFAEEVE | KPTKCGCAQC | A

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00008

STRING:

10090.ENSMUSP00000025993

String:

Q80TR4

SMR:

Q80TR4

UniGene:

Mm.40322

KEGG:

mmu:20562

Uniprot:

Q80TR4

FOR

ELISA Kit for Mouse Slit-1

CLIA Kit for Mouse Slit-1

Polyclonal Antibody for Mouse Slit-1

Monoclonal Antibody for Mouse Slit-1

Protein for Mouse Slit-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The mouse SLIT family: secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis and axon guidance."
Yuan W. , Zhou L. , Chen J.H. , Wu J.Y. , Rao Y. , Ornitz D.M.
Dev. Biol.212:290-306(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH ROBO1;DEVELOPMENTAL STAGE
strain: ICR X Swiss Webster.
2.

"Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Aizawa H. , Yuasa S. , Nakajima D. , Nagase T. , Ohara O. , Koga H.
DNA Res.10:35-48(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6.
tissue: Brain.
4.

"Slit1 and slit2 proteins control the development of the lateral olfactory tract."
Nguyen-Ba-Charvet K.T. , Plump A.S. , Tessier-Lavigne M. , Chedotal A.
J. Neurosci.22:5473-5480(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
5.

"Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain."
Bagri A. , Marin O. , Plump A.S. , Mak J. , Pleasure S.J. , Rubenstein J.L. , Tessier-Lavigne M.
Neuron33:233-248(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
6.

"Retinal ganglion cell axon guidance in the mouse optic chiasm: expression and function of robos and slits."
Erskine L. , Williams S.E. , Brose K. , Kidd T. , Rachel R.A. , Goodman C.S. , Tessier-Lavigne M. , Mason C.A.
J. Neurosci.20:4975-4982(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE

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