SMAD4 ELISA Kit for Bovine(Bos taurus) | EIAab.comSMAD4 ELISA Kit for Bovine(Bos taurus)

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Index > Protein center > SMAD4(Gene name) > Bovine

SMAD4 (Gene name),

Mothers against decapentaplegic homolog 4 (Protein name ), SMAD4_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

SMAD4;

Protein name:

Mothers against decapentaplegic homolog 4(MAD homolog 4;Mothers against DPP homolog 4);

Alternative:

SMAD family member 4(SMAD 4;Smad4);

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Monomer (By similarity). Heterotrimer; with a C-terminally phosphorylated R-SMAD molecule and to form the transcriptionally active SMAD2/3-SMAD4 complex (By similarity). Found in a ternary complex composed of SMAD4, STK11/LKB1 and STK11IP. Interacts with ATF2, COPS5, DACH1, MSG1, SKI, STK11/LKB1, STK11IP and TRIM33. Associates with ZNF423 or ZNF521 in response to BMP2 leading to activate transcription of BMP target genes. Interacts with USP9X. Interacts with RBPMS. Interacts with WWTR1 (via coiled-coil domain). Interacts with CITED1 and CITED2.

Function:

Common SMAD (co-SMAD) is the coactivator and mediator of signal transduction by TGF-beta (transforming growth factor). Component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling. Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. Component of the multimeric SMAD3/SMAD4/JUN/FOS complex which forms at the AP1 promoter site; required for syngernistic transcriptional activity in response to TGF-beta. May act as a tumor suppressor.

Subcellular Location:

Cytoplasm Nucleus Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with R-SMAD.

Protein Attributes:

Sequence length:

553

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

553:

PLD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

bta:540248

UniGene:

Bt.13220

SMR:

Q1HE26

String:

Q1HE26

Pfam:

PF03165

Uniprot:

Q1HE26

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ELISA Kit for Bovine MAD homolog 4

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ELISA Kit for Bovine MAD homolog 4

Cat.:

E1925r

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MSDS:

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Packing:

96T

ELISA Kit for Bovine MAD homolog 4

Cat.:

E1925b

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Packing:

96T

ELISA Kit for Bovine MAD homolog 4

Cat.:

E1925m

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Packing:

96T

ELISA Kit for Bovine MAD homolog 4

Cat.:

E1925p

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MSDS:

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Packing:

96T

CLIA Kit for Bovine MAD homolog 4

Cat.:

U1925m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Bovine MAD homolog 4

Cat.:

U1925b

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine MAD homolog 4

Cat.:

U1925h

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine MAD homolog 4

Cat.:

U1925p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine MAD homolog 4

Cat.:

U1925r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Bovine MAD homolog 4

Cat.:

P1925Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine MAD homolog 4

Cat.:

P1925Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine MAD homolog 4

Cat.:

P1925Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Bovine MAD homolog 4

Protein for Bovine MAD homolog 4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and bioinformatic analysis of cDNA encoding cattle SMAD4 gene."
Zhang X. , Xu S. , Zhang L. , Gao X. , Ren H. , Chen J.
Submitted (2006-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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