Gene name:
SMC2 (SCII;SMC2L1) ;
Protein name:
Structural maintenance of chromosomes protein 2 (SMC protein 2;SMC-2) ;
Alternative:
Chromosome scaffold protein ScII ;
Organism:
Chicken (Gallus gallus).
General Annotation
Sub Unit:
Forms an heterodimer with SMC4. Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and probably some non SMC subunits that regulate the complex.
Function:
Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Subcellular Location:
Nucleus
Cytoplasm
Chromosome
In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, condensin associates with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
Protein Attributes:
50:
MYIKSIVLEG | FKSYAQRTEI | RDFDPLFNAI | TGLNGSGKSN | ILDSICFLLG |
100:
ISNLSQVRAS | SLQDLVYKNG | QAGVNKATVS | ITFDNSDKKN | SPLGFENNDE |
150:
ITITRQVIVG | GRNKYLINGM | NASNNRVQDL | FGSVGLNVNN | PHFLIMQGQI |
200:
TKVLNMKPTE | ILAMIEEAAG | TRMYECKKIT | AHKTIEKKES | KLDEIRRIIT |
250:
EEISPTLEKL | KEARASYLEY | QKMTREVENL | RRIYVAFQYV | RAEEIKDRST |
300:
NALKEAQANK | KKIFESMAEN | EKKVKELAQQ | IEETEKKNNE | EFGAKLHSLE |
350:
AAFSELQRVD | AKVRSDLDHR | KQNLNSEENR | LKELIKIMQE | EFKAFTSKEK |
400:
EIKKIKEGLN | GLQEESKKDA | EALASAQQHF | NAVSAGLSSN | DSGQGTSLAD |
450:
QMMTCKNEIS | KAATEAKQAQ | MKLKYAQQEL | KTKQAEVKKM | DGSYKEDQEA |
500:
FEAIRKTKEK | LQDEMKKLKY | EEAEQEAHLA | KKKQLSSEIS | SLRELCESIE |
550:
AKHPYLRFEY | KNPEKNWNPN | CVKGLVVTLI | TVKDISTSKA | LEAVAGGKLY |
600:
NIVVDTEATG | KKILEKGQLK | HRYTIIPLSK | ISANSIGHEI | ISLAKNLIGH |
650:
REVHIAISLI | DYNSELQKAM | EYVFGTTLVC | SSMDNAKKVT | FDKRIMRKTV |
700:
TLQGDIFDPQ | GTLSGGASSH | VTPILSKLKT | MRDAEDELKI | KTSQLEATEK |
750:
ELANLKNMAE | KYQHLKQQWE | MKSEEAELLQ | TKIQQSAYHK | QQEDLLALKK |
800:
TIAECEETLK | KTEESQRKAE | EEYKALENKM | KNAEAERGKE | IKNAQQKLNS |
850:
AKKKADDSSR | KMKEKQQEVE | ALVLELEQLK | QEQASYKQQS | EAAQQAIASL |
900:
KEQVSALEAE | AVKTRESLKN | AENELSSEKG | LMEERTKDIK | AKSAKIEKYR |
950:
EQNNELQLSI | NALEHDINKY | QQETADASST | LDKLLKEYKW | IASEKELFGQ |
1000:
ADTTYDFEAN | NPKETGQKLQ | KLLTKKEKLE | KSLNMRAMNL | LSEAEERYND |
1050:
LMKKKRMVEN | DKIKILATIE | ELDRKKNKAL | HIAWEKVNKD | FGSIFSMLLP |
1100:
GAKAMLVPSK | KQNILDGLEF | RVGLGDIWKE | NLTELSGGQR | SLAALSLILA |
1150:
ILLFKPAPIY | ILDEVDAALD | LSHTQNIGQM | LHAHFKQSQF | LVVSLKDGMF |
1189:
NNANVLYRTK | FVDGISTVSR | HCQLKKKQPL | SEASNNKDE
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Chicken
ELISA Kit for Chicken SMC protein 2
ELISA Kit for Chicken SMC protein 2
ELISA Kit for Chicken SMC protein 2
CLIA Kit for Chicken SMC protein 2
CLIA Kit for Chicken SMC protein 2
CLIA Kit for Chicken SMC protein 2
Polyclonal Antibody for Chicken SMC protein 2
Polyclonal Antibody for Chicken SMC protein 2
Polyclonal Antibody for Chicken SMC protein 2
Monoclonal Antibody for Chicken SMC protein 2
Monoclonal Antibody for Chicken SMC protein 2
Monoclonal Antibody for Chicken SMC protein 2
Protein for Chicken SMC protein 2
Protein for Chicken SMC protein 2
Protein for Chicken SMC protein 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Fibroblast .