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Index > Protein center > Smn1(Gene name) > Rat
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  • Smn1 (Gene name),
  • Survival motor neuron protein (Protein name ),  SMN_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Smn1(Smn);
    Protein name:
    Survival motor neuron protein;
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Component of an import snRNP complex composed of KPNB1, RNUT1, SMN1 and ZNF259. Part of the core SMN complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8 and STRAP/UNRIP. Interacts with DDX20, FBL, NOLA1, RNUT1, SYNCRIP and with several spliceosomal snRNP core Sm proteins, including SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE and ILF3. Interacts with OSTF1, LSM10 and LSM11.
    Function:
    The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs.
    Subcellular Location:
    Cytoplasm Nucleus gem Localized in subnuclear structures next to coiled bodies, called Gemini of Cajal bodies (Gems).
    Protein Attributes:
    Sequence length:
    289
    Sequence:
    50:
    MAMGSGGGAG | SEQEDTVLFR | RGTGQSDDSD | IWDDTALIKA | YDKAVASFKH | 
    100:
    ALKNGDMCET | SDKPKGTARR | KPAKKNKNQK | KNATAPLKQW | KAGDKCSAVW | 
    150:
    SEDGCVYPAT | ITSVDLKRET | CVVVYTGYGN | KEEQNLSDLL | SPTCEVANNT | 
    200:
    EQNTQENESQ | VSTDDSEHSS | RSLRSKAHSK | SKAAPWTSFL | PPPPPVPGAG | 
    250:
    LGPGKPGLRF | SGPPPPPPPP | PPFLPCWMPP | FPSGPPIIPP | PPPISPDCLD | 
    289:
    DTDALGSMLI | SWYMSGYHTG | YYMGFRQNKK | EGKKCSHTN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    SMR:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Survival motor neuron protein
    ELISA Kit for Rat Survival motor neuron protein
    ELISA Kit for Rat Survival motor neuron protein
    ELISA Kit for Rat Survival motor neuron protein
    ELISA Kit for Rat Survival motor neuron protein
    CLIA Kit for Rat Survival motor neuron protein
    CLIA Kit for Rat Survival motor neuron protein
    CLIA Kit for Rat Survival motor neuron protein
    CLIA Kit for Rat Survival motor neuron protein
    CLIA Kit for Rat Survival motor neuron protein
    Polyclonal Antibody for Rat Survival motor neuron protein
    Polyclonal Antibody for Rat Survival motor neuron protein
    Polyclonal Antibody for Rat Survival motor neuron protein
    Polyclonal Antibody for Rat Survival motor neuron protein
    Polyclonal Antibody for Rat Survival motor neuron protein
    Monoclonal Antibody for Rat Survival motor neuron protein
    Monoclonal Antibody for Rat Survival motor neuron protein
    Monoclonal Antibody for Rat Survival motor neuron protein
    Monoclonal Antibody for Rat Survival motor neuron protein
    Monoclonal Antibody for Rat Survival motor neuron protein
    Protein for Rat Survival motor neuron protein
    Protein for Rat Survival motor neuron protein
    Protein for Rat Survival motor neuron protein
    Protein for Rat Survival motor neuron protein
    Protein for Rat Survival motor neuron protein

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Expression of the SMN gene, the spinal muscular atrophy determining gene, in the mammalian central nervous system."
      Battaglia G. , Princivalle A. , Forti F. , Lizier C. , Zeviani M.
      Hum. Mol. Genet.6:1961-1971(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Liver.
    2. 2.
      "Survival motor neuron (SMN) protein in rat is expressed as different molecular forms and is developmentally regulated."
      La Bella V. , Cisterni C. , Salaun D. , Pettmann B.
      Eur. J. Neurosci.10:2913-2923(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
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