Gene name:
SMOX (UNQ3039/PRO9854;C20orf16;SMO) ;
Protein name:
Spermine oxidase ;
Alternative:
Polyamine oxidase 1 (PAO-1;PAOh1) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal.
Subcellular Location:
Isoform 6
Cytoplasm
Nucleus
Protein Attributes:
50:
MQSCESSGDS | ADDPLSRGLR | RRGQPRVVVI | GAGLAGLAAA | KALLEQGFTD |
100:
VTVLEASSHI | GGRVQSVKLG | HATFELGATW | IHGSHGNPIY | HLAEANGLLE |
150:
ETTDGERSVG | RISLYSKNGV | ACYLTNHGRR | IPKDVVEEFS | DLYNEVYNLT |
200:
QEFFRHDKPV | NAESQNSVGV | FTREEVRNRI | RNDPDDPEAT | KRLKLAMIQQ |
250:
YLKVESCESS | SHSMDEVSLS | AFGEWTEIPG | AHHIIPSGFM | RVVELLAEGI |
300:
PAHVIQLGKP | VRCIHWDQAS | ARPRGPEIEP | RGEGDHNHDT | GEGGQGGEEP |
350:
RGGRWDEDEQ | WSVVVECEDC | ELIPADHVIV | TVSLGVLKRQ | YTSFFRPGLP |
400:
TEKVAAIHRL | GIGTTDKIFL | EFEEPFWGPE | CNSLQFVWED | EAESHTLTYP |
450:
PELWYRKICG | FDVLYPPERY | GHVLSGWICG | EEALVMEKCD | DEAVAEICTE |
500:
MLRQFTGNPN | IPKPRRILRS | AWGSNPYFRG | SYSYTQVGSS | GADVEKLAKP |
550:
LPYTESSKTA | PMQVLFSGEA | THRKYYSTTH | GALLSGQREA | ARLIEMYRDL |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Spermine oxidase
ELISA Kit for Human Spermine oxidase
CLIA Kit for Human Spermine oxidase
CLIA Kit for Human Spermine oxidase
Polyclonal Antibody for Human Spermine oxidase
Polyclonal Antibody for Human Spermine oxidase
Monoclonal Antibody for Human Spermine oxidase
Monoclonal Antibody for Human Spermine oxidase
Protein for Human Spermine oxidase
Protein for Human Spermine oxidase
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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