Protein name:
Smoothelin-like protein 1 ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with PPP1R12A.
Function:
Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-299 reduces this inhibitory activity.
Subcellular Location:
Cytoplasm
myofibril
Cytoplasm
myofibril
sarcomere
I band
Cytoplasm
myofibril
sarcomere
M line
Nucleus
Colocalizes with MYH2. In its unphosphorylated state, localizes to the cytoplasm (By similarity). Phosphorylation at Ser-301 promotes translocation to the nucleus.
Protein Attributes:
50:
MEQKEGKLSE | DGTTVSPAAD | NPEMSGGGAP | AEETKGTAGK | AINEGPPTES |
100:
GKQEKAPAED | GMSAELQGEA | NGLDEVKVES | QREAGGKEDA | EAELKKEDGE |
150:
KEETTVGSQE | MTGRKEETKS | EPKEAEEKES | TLASEKQKAE | EKEAKPESGQ |
200:
KADANDRDKP | EPKATVEEED | AKTASQEETV | VEDEAKAEPK | EPDGKEEAKH |
250:
GAKEEADEPG | SPSEEQEQDV | EKEPEGGAGV | IPSSPEEWPE | SPTGEGHNLS |
300:
TDGLGPDCVA | SGQTSPSASE | SSPSDVPQSP | PESPSSGEKK | EKAPERRVSA |
350:
PARPRGPRAQ | NRKAIVDKFG | GAASGPTALF | RNTKAAGAAI | GGVKNMLLEW |
400:
CRAMTKKYEH | VDIQNFSSSW | SSGMAFCALI | HKFFPDAFDY | AELDPAKRRH |
450:
NFTLAFSTAE | KLADCAQLLD | VDDMVRLAVP | DSKCVYTYIQ | ELYRSLVQKG |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human Smoothelin-like protein 1
ELISA Kit for Human Smoothelin-like protein 1
CLIA Kit for Human Smoothelin-like protein 1
CLIA Kit for Human Smoothelin-like protein 1
Polyclonal Antibody for Human Smoothelin-like protein 1
Polyclonal Antibody for Human Smoothelin-like protein 1
Monoclonal Antibody for Human Smoothelin-like protein 1
Monoclonal Antibody for Human Smoothelin-like protein 1
Protein for Human Smoothelin-like protein 1
Protein for Human Smoothelin-like protein 1
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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"Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle."
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J. Biol. Chem.283:11850-11859(2008)
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;TISSUE SPECIFICITY
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY