Snx1 ELISA Kit for Mouse(Mus musculus) | EIAab.comSnx1 ELISA Kit for Mouse(Mus musculus)

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Snx1 (Gene name),

Sorting nexin-1 (Protein name ), SNX1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Snx1;

Protein name:

Sorting nexin-1;

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Self-assembles into a complex of approximately 300 kDa. Interacts with HGS. Component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts with SNX6.

Function:

May be involved in several stages of intracellular trafficking. Plays a role in targeting ligand-activated EGFR to the lysosomes for degradation after endocytosis from the cell surface and release from the Golgi. Component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).

Subcellular Location:

Endosome membrane Peripheral membrane protein Cytoplasmic side Golgi apparatus trans-Golgi network membrane Peripheral membrane protein Cytoplasmic side Early endosome membrane Peripheral membrane protein Cytoplasmic side Enriched on tubular elements of the early endosome membrane. Binds preferentially to highly curved membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).

Protein Attributes:

Sequence length:

522

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

522:

LHSQQQLAKY | WEAFLPEAKA | IS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.271891

Pfam:

PF00787

KEGG:

mmu:56440

String:

Q9WV80

SMR:

Q9WV80

Uniprot:

Q9WV80

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ELISA Kit for Mouse Sorting nexin-1

Cat.:

E15090h

Price:

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Mouse Sorting nexin-1

MSDS:

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ELISA Kit for Mouse Sorting nexin-1

MSDS:

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ELISA Kit for Mouse Sorting nexin-1

MSDS:

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CLIA Kit for Mouse Sorting nexin-1

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CLIA Kit for Mouse Sorting nexin-1

MSDS:

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CLIA Kit for Mouse Sorting nexin-1

MSDS:

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CLIA Kit for Mouse Sorting nexin-1

Cat.:

U15090h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Sorting nexin-1

Monoclonal Antibody for Mouse Sorting nexin-1

Protein for Mouse Sorting nexin-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Complete sequence of mouse sorting nexin 1 (Snx1) cDNA."
Takahara K. , Omatsu Y. , Maeda Y. , Shimoyama S. , Inaba K.
Submitted (1999-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Thymus.
2.

"Association of mouse sorting nexin 1 with early endosomes."
Nakamura N. , Sun-Wada G.H. , Yamamoto A. , Wada Y. , Futai M.
J. Biochem.130:765-771(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBUNIT
strain: C57BL/6.
3.

"Genetic analysis of sorting nexins 1 and 2 reveals a redundant and essential function in mice."
Schwarz D.G. , Griffin C.T. , Schneider E.A. , Yee D. , Magnuson T.
Mol. Biol. Cell13:3588-3600(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
4.

"Large-scale phosphorylation analysis of mouse liver."
Villen J. , Beausoleil S.A. , Gerber S.A. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-188;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.

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