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Index > Protein center > SOAT2(Gene name) > Human
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  • SOAT2 (Gene name),
  • Sterol O-acyltransferase 2 (Protein name ),  SOAT2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SOAT2(ACACT2;ACAT2);
    Protein name:
    Sterol O-acyltransferase 2;
    Alternative:
    Cholesterol acyltransferase 2;Acyl-coenzyme A:cholesterol acyltransferase 2(ACAT-2);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    May form homo- or heterodimers.
    Function:
    Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    522
    Sequence:
    50:
    MEPGGARLRL | QRTEGLGGER | ERQPCGDGNT | ETHRAPDLVQ | WTRHMEAVKA | 
    100:
    QLLEQAQGQL | RELLDRAMRE | AIQSYPSQDK | PLPPPPPGSL | SRTQEPSLGK | 
    150:
    QKVFIIRKSL | LDELMEVQHF | RTIYHMFIAG | LCVFIISTLA | IDFIDEGRLL | 
    200:
    LEFDLLIFSF | GQLPLALVTW | VPMFLSTLLA | PYQALRLWAR | GTWTQATGLG | 
    250:
    CALLAAHAVV | LCALPVHVAV | EHQLPPASRC | VLVFEQVRFL | MKSYSFLREA | 
    300:
    VPGTLRARRG | EGIQAPSFSS | YLYFLFCPTL | IYRETYPRTP | YVRWNYVAKN | 
    350:
    FAQALGCVLY | ACFILGRLCV | PVFANMSREP | FSTRALVLSI | LHATLPGIFM | 
    400:
    LLLIFFAFLH | CWLNAFAEML | RFGDRMFYRD | WWNSTSFSNY | YRTWNVVVHD | 
    450:
    WLYSYVYQDG | LRLLGARARG | VAMLGVFLVS | AVAHEYIFCF | VLGFFYPVML | 
    500:
    ILFLVIGGML | NFMMHDQRTG | PAWNVLMWTM | LFLGQGIQVS | LYCQEWYARR | 
    522:
    HCPLPQATFW | GLVTPRSWSC | HT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    String:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Sterol O-acyltransferase 2
    ELISA Kit for Human Sterol O-acyltransferase 2
    ELISA Kit for Human Sterol O-acyltransferase 2
    CLIA Kit for Human Sterol O-acyltransferase 2
    CLIA Kit for Human Sterol O-acyltransferase 2
    CLIA Kit for Human Sterol O-acyltransferase 2
    Polyclonal Antibody for Human Sterol O-acyltransferase 2
    Polyclonal Antibody for Human Sterol O-acyltransferase 2
    Polyclonal Antibody for Human Sterol O-acyltransferase 2
    Monoclonal Antibody for Human Sterol O-acyltransferase 2
    Monoclonal Antibody for Human Sterol O-acyltransferase 2
    Monoclonal Antibody for Human Sterol O-acyltransferase 2
    Protein for Human Sterol O-acyltransferase 2
    Protein for Human Sterol O-acyltransferase 2
    Protein for Human Sterol O-acyltransferase 2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes."
      Oelkers P. , Behari A. , Cromley D. , Billheimer J.T. , Sturley S.L.
      J. Biol. Chem.273:26765-26771(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Immunological quantitation and localization of ACAT-1 and ACAT-2 in human liver and small intestine."
      Chang C.C.Y. , Sakashita N. , Ornvold K. , Lee O. , Chang E.T. , Dong R. , Lin S. , Lee C.-Y.G. , Strom S.C. , Kashyap R. , Fung J.J. , Farese R.V. Jr. , Patoiseau J.-F. , Delhon A. , Chang T.-Y.
      J. Biol. Chem.275:28083-28092(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT ILE-254
      tissue: Intestine.
    3. 3.
      "Structure of the human acyl-CoA:cholesterol acyltransferase-2 (ACAT-2) gene and its relation to dyslipidemia."
      Katsuren K. , Tamura T. , Arashiro R. , Takata K. , Matsuura T. , Niikawa N. , Ohta T.
      Biochim. Biophys. Acta1531:230-240(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Organization of human ACAT-2 gene and its cell-type-specific promoter activity."
      Song B.L. , Qi W. , Yang X.Y. , Chang C.C.Y. , Zhu J.Q. , Chang T.Y. , Li B.L.
      Biochem. Biophys. Res. Commun.282:580-588(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 4);VARIANTS GLY-14 AND ILE-254
    7. 7.
      "Two human ACAT2 mRNA variants produced by alternative splicing and coding for novel isoenzymes."
      Yao X.M. , Wang C.H. , Song B.L. , Yang X.Y. , Wang Z.Z. , Qi W. , Lin Z.X. , Chang C.C. , Chang T.Y. , Li B.L.
      Acta Biochim. Biophys. Sin.37:797-806(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;ALTERNATIVE SPLICING (ISOFORMS 2 AND 3)
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