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Index > Protein center > Socs2(Gene name) > Mouse
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  • Socs2 (Gene name),
  • Suppressor of cytokine signaling 2 (Protein name ),  SOCS2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Socs2(Cis2;Cish2);
    Protein name:
    Suppressor of cytokine signaling 2(SOCS-2);
    Alternative:
    Cytokine-inducible SH2 protein 2(CIS-2);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Associates with the Elongin BC complex.
    Function:
    SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    198
    Sequence:
    50:
    MTLRCLEPSG | NGADRTRSQW | GTAGLPEEQS | PEAARLAKAL | RELSQTGWYW | 
    100:
    GSMTVNEAKE | KLKEAPEGTF | LIRDSSHSDY | LLTISVKTSA | GPTNLRIEYQ | 
    150:
    DGKFRLDSII | CVKSKLKQFD | SVVHLIDYYV | QMCKDKRTGP | EAPRNGTVHL | 
    198:
    YLTKPLYTSA | PTLQHFCRLA | INKCTGTIWG | LPLPTRLKDY | LEEYKFQV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse SOCS-2
    Cat.:
    E1415h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse SOCS-2
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    E1415m
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    96T
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    ELISA Kit for Mouse SOCS-2
    Cat.:
    E1415r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse SOCS-2
    Cat.:
    E1415b
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse SOCS-2
    Cat.:
    E1415p
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse SOCS-2
    Cat.:
    U1415r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse SOCS-2
    Cat.:
    U1415m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse SOCS-2
    Cat.:
    U1415h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse SOCS-2
    Cat.:
    U1415p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse SOCS-2
    Cat.:
    U1415b
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse SOCS-2
    Polyclonal Antibody for Mouse SOCS-2
    Cat.:
    P1415Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse SOCS-2
    Cat.:
    P1415Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse SOCS-2
    Polyclonal Antibody for Mouse SOCS-2
    Cat.:
    P1415Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse SOCS-2
    Monoclonal Antibody for Mouse SOCS-2
    Monoclonal Antibody for Mouse SOCS-2
    Monoclonal Antibody for Mouse SOCS-2
    Monoclonal Antibody for Mouse SOCS-2
    Protein for Mouse SOCS-2
    Protein for Mouse SOCS-2
    Protein for Mouse SOCS-2
    Protein for Mouse SOCS-2
    Protein for Mouse SOCS-2

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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Thymus.
    2. 2.
      "Expression of 'suppressor of cytokine signaling' (SOCS) genes in the developing and adult mouse nervous system."
      Polizzotto M.N. , Bartlett P.F. , Turnley A.M.
      J. Comp. Neurol.423:348-358(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE
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