Protein name:
Sorcin ;
Alternative:
CP-22 (CP22) ;22 kDa protein ;V19 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Homodimer. Interacts with GCA, RYR2 and ANXA7.
Function:
Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels.
Subcellular Location:
Cytoplasm
Sarcoplasmic reticulum membrane
Peripheral membrane protein
Cytoplasmic side
Relocates to the sarcoplasmic reticulum membrane in response to elevated calcium levels.
Protein Attributes:
50:
MAYPGHPGAG | GGYYPGGYGG | APGGPAFPGQ | TQDPLYGYFA | AVAGQDGQID |
100:
ADELQRCLTQ | SGIAGGYKPF | NLETCRLMVS | MLDRDMSGTM | GFNEFKELWA |
150:
VLNGWRQHFI | SFDTDRSGTV | DPQELQKALT | TMGFRLSPQA | VNSIAKRYST |
198:
NGKITFDDYI | ACCVKLRALT | DSFRRRDTAQ | QGVVNFPYDD | FIQCVMSV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Sorcin
ELISA Kit for Human Sorcin
CLIA Kit for Human Sorcin
CLIA Kit for Human Sorcin
Polyclonal Antibody for Human Sorcin
Polyclonal Antibody for Human Sorcin
Monoclonal Antibody for Human Sorcin
Monoclonal Antibody for Human Sorcin
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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FASEB J.22:295-306(2008)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF MUTANT LEU-112;SUBUNIT;FUNCTION;CALCIUM-BINDING;INTERACTION WITH RYR2 AND ANXA7