Protein name:
Sortilin-related receptor ;
Alternative:
SorLA-1 ;Low-density lipoprotein receptor relative with 11 ligand-binding repeats (LDLR relative with 11 ligand-binding repeats;LR11) ;Sorting protein-related receptor containing LDLR class A repeats (SorLA) ;
Organism:
Chicken (Gallus gallus).
General Annotation
Function:
Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. Both estrogen status and cholesterol levels lack regulatory effects on this receptor.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
GWVSLNDSHN | QMVVHWAGEK | SNVIVALARD | SLSLLGPKNS | DVYISYDYGK |
100:
SFKKISERFS | FGDGNSSAVA | IAQFYHSPAN | NQRYIFVDAF | VPYLWITTDF |
150:
CKSIQGFSIP | FRAADLLLHS | RNPNLVLGFD | RSHPNKQLWK | SDDFGQTWIM |
200:
IQEHVKSFSW | GVEPYDKPNT | VYIERHEPSG | TSTVIRSTDF | FQSRENKEVI |
250:
LEDVDDFQLR | DKYLFATKAV | RLLGSLQPSS | VQLWVSFNRK | PMRVAQFVTK |
300:
HPIKEYYIAD | ASEDQVFVCV | SHDDNRTNLY | ISEAEGLKFS | LSLENVLYYS |
350:
PGGAGSDTLV | RYFANEPFAD | FHRVEGVRGV | YIATLLNGSF | SEENMRSVIT |
400:
FDKGGTWEPL | QPPAETRYGE | KTHCELSQGC | SLHLAQRLSQ | LLNFQLRRMP |
450:
ILSKESAPGL | IIATGSIGKS | MAKKTNVYIS | SSAGARWREA | LSGPHYYTWG |
500:
DHGGILVAIA | QGTETDQLKY | STNEGETWKS | FTFSEKPVFV | YGLLTEPGEK |
550:
STIFTIFGSY | KENGHSWLIL | QVNTSDVLGV | PCTENDYKLW | SPSDERGNEC |
600:
LLGHKTVFKR | RTPHATCFNG | EDFDRPVMVS | NCSCTREDFE | CDFGFKLSED |
650:
LSLEVCVPDP | EFAGKPYDPP | VPCPVGSTYR | RTRGYRKISG | DTCMGGDIES |
700:
RLEGEMLPCP | LAEENEFILY | ATRYSIHRYD | LASGLSQELP | LAGLRGAVAL |
750:
DFDYEHNCLY | WADVTLDIIQ | RLCLNGSSGQ | EIIISTGLET | VEALAFEPLS |
800:
QLLYWVNAGI | PKIEVANPDG | DLRLTVLNSS | VLERPRALAL | VPREGLMFWT |
850:
DWGDSRPGIY | RSDMDGSLAA | CIVSEGVRWP | NGISVDDHWI | YWTEAYMDRI |
900:
ERVDFNGLQR | SVILDSLPHP | YAIAVFKNEI | YWNDWSQLSI | FRASKNSGSR |
950:
METLVGRLYG | IMDMKIFYRG | KTTGQNACIA | HPCSLLCLPK | SNNGRSCKCP |
1000:
EGVSSTVLPS | GEVKCDCPHG | YSMKNNTCVK | EENTCLPNQY | RCFNGNCINS |
1050:
IWQCDNNNDC | GDMSDEKNCP | TTVCDAETQF | RCRESGTCIP | LSYKCDLEDD |
1100:
CGDNSDESHC | EAHQCRKDEF | SCSSGMCIRL | SWRCDDDNDC | RDWSDEANCT |
1150:
MFRTCEASSF | QCLNGHCIPQ | RWACDGDADC | QDGSDEDPTI | CEKKCNGFQC |
1200:
PNGTCISTSK | HCNGITDCAD | ASDEQDCEIP | LCTRYMDFVC | KNRQQCLSHS |
1250:
MVCDGDIQCE | DGSDEDANYA | GCAQEPEFHR | TCDQFSFQCA | NGVCISLVWK |
1300:
CDGMDDCGDY | SDEASCENPT | DAPTCSRYYQ | FQCGNGHCIP | NQWKCDGEND |
1350:
CGDWSDEKEC | EGSPLLPITT | AVPPTCLPNH | FRCGSGACIT | NSWVCDGYRD |
1400:
CADGSDEDAC | PTSHPNVTSS | PPAPRGRCSR | TEFECQQLHK | CIPNWKRCDG |
1450:
RRDCQDGTDE | RSCPTHSSLS | CPQGYRCEDG | EACLLATERC | DGYLDCSDGS |
1500:
DERNCTDDTI | VYKVQNLQWT | ADFSGAITLT | WARPKRMSST | SCVYNVYYRM |
1550:
VGESIWKVLE | THSNKTSSVL | KVLKPDCTYQ | VKVQVQCLSR | VYNTNDFITL |
1592:
RVPEGLPDAP | FNLQLALKKE | AEGVVLCSWS | APVNAHGLIR | EP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Chicken
Mouse
Rabbit
ELISA Kit for Chicken Sortilin-related receptor
ELISA Kit for Chicken Sortilin-related receptor
ELISA Kit for Chicken Sortilin-related receptor
ELISA Kit for Chicken Sortilin-related receptor
CLIA Kit for Chicken Sortilin-related receptor
CLIA Kit for Chicken Sortilin-related receptor
CLIA Kit for Chicken Sortilin-related receptor
CLIA Kit for Chicken Sortilin-related receptor
Polyclonal Antibody for Chicken Sortilin-related receptor
Polyclonal Antibody for Chicken Sortilin-related receptor
Polyclonal Antibody for Chicken Sortilin-related receptor
Polyclonal Antibody for Chicken Sortilin-related receptor
Monoclonal Antibody for Chicken Sortilin-related receptor
Monoclonal Antibody for Chicken Sortilin-related receptor
Monoclonal Antibody for Chicken Sortilin-related receptor
Monoclonal Antibody for Chicken Sortilin-related receptor
Protein for Chicken Sortilin-related receptor
Protein for Chicken Sortilin-related receptor
Protein for Chicken Sortilin-related receptor
Protein for Chicken Sortilin-related receptor
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Brain .