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Index > Protein center > Sorl1(Gene name) > Mouse
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  • Sorl1 (Gene name),
  • Sortilin-related receptor (Protein name ),  SORL_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Sorl1;
    Protein name:
    Sortilin-related receptor;
    Alternative:
    Low-density lipoprotein receptor relative with 11 ligand-binding repeats(LDLR relative with 11 ligand-binding repeats;LR11);Gp250;Sorting protein-related receptor containing LDLR class A repeats(mSorLA);SorLA-1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with GGA1 and ROCK2.
    Function:
    Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. May play a role in neural organization, as well as the establishment of embryonic organ systems.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    2215
    Sequence:
    50:
    MATRSSRRES | RLPFLFALVA | LLPRGALGGG | WTQRLHGGPA | PLPQDRGFFV | 
    100:
    VQGDPRDLRL | GTHGDAPGAS | PAARKPLRTR | RSAALQPQPI | QVYGQVSLND | 
    150:
    SHNQMVVHWA | GEKSNVIVAL | ARDSLALARP | KSSDVYVSYD | YGKSFSKISE | 
    200:
    KLNFGVGNNS | EAVISQFYHS | PADNKRYIFV | DAYAQYLWIT | FDFCSTIHGF | 
    250:
    SIPFRAADLL | LHSKASNLLL | GFDRSHPNKQ | LWKSDDFGQT | WIMIQEHVKS | 
    300:
    FSWGIDPYDQ | PNAIYIERHE | PFGFSTVLRS | TDFFQSRENQ | EVILEEVRDF | 
    350:
    QLRDKYMFAT | KVVHLPGSQQ | QSSVQLWVSF | GRKPMRAAQF | VTKHPINEYY | 
    400:
    IADAAEDQVF | VCVSHSNNST | NLYISEAEGL | KFSLSLENVL | YYSPGGAGSD | 
    450:
    TLVRYFANEP | FADFHRVEGL | QGVYIATLIN | GSMNEENMRS | VITFDKGGTW | 
    500:
    EFLQAPAFTG | YGEKINCELS | QGCSLHLAQR | LSQLLNLQLR | RMPILSKESA | 
    550:
    PGLIIATGSV | GKNLASKTNV | YISSSAGARW | REALPGPHYY | TWGDHGGIIM | 
    600:
    AIAQGMETNE | LKYSTNEGET | WKTFVFSEKP | VFVYGLLTEP | GEKSTVFTIF | 
    650:
    GSNKESVHSW | LILQVNATDA | LGVPCTENDY | KLWSPSDERG | NECLLGHKTV | 
    700:
    FKRRTPHATC | FNGEDFDRPV | VVSNCSCTRE | DYECDFGFKM | SEDLSLEVCV | 
    750:
    PDPEFSGKPY | SPPVPCPVGS | SYRRTRGYRK | ISGDTCSGGD | VEARLEGELV | 
    800:
    PCPLAEENEF | ILYAMRKSIY | RYDLASGATE | QLPLSGLRAA | VALDFDYERN | 
    850:
    CLYWSDLALD | TIQRLCLNGS | TGQEVIINSG | LETVEALAFE | PLSQLLYWVD | 
    900:
    AGFKKIEVAN | PDGDFRLTIV | NSSVLDRPRA | LVLVPQEGVM | FWTDWGDLKP | 
    950:
    GIYRSYMDGS | AAYRLVSEDV | KWPNGISVDS | QWIYWTDAYL | DCIERITFSG | 
    1000:
    QQRSVILDSL | PHPYAIAVFK | NEIYWDDWSQ | LSIFRASKHS | RSQVEILASQ | 
    1050:
    LTGLMDMKVF | YKGKNAGSNA | CVPQPCSLLC | LPKANNSKSC | RCPEGVASSV | 
    1100:
    LPSGDLMCDC | PQGYQRKNNT | CVKEENTCLR | NQYRCSNGNC | INSIWWCDFD | 
    1150:
    NDCGDMSDER | NCPTTVCDAD | TQFRCQESGT | CIPLSYKCDL | EDDCGDNSDE | 
    1200:
    SHCEMHQCRS | DEFNCSSGMC | IRSSWVCDGD | NDCRDWSDEA | NCTAIYHTCE | 
    1250:
    ASNFQCHNGH | CIPQRWACDG | DADCQDGSDE | DPVSCEKKCN | GFHCPNGTCI | 
    1300:
    PSSKHCDGLR | DCPDGSDEQH | CEPFCTRFMD | FVCKNRQQCL | FHSMVCDGIV | 
    1350:
    QCRDGSDEDA | AFAGCSQDPE | FHKECDEFGF | QCQNGVCISL | IWKCDGMDDC | 
    1400:
    GDYSDEANCE | NPTEAPNCSR | YFQFHCENGH | CIPNRWKCDR | ENDCGDWSDE | 
    1450:
    KDCGDSHVLP | SPTPGPSTCL | PNYFHCSSGA | CVMGTWVCDG | YRDCADGSDE | 
    1500:
    EACPSLANST | AASTPTQFGQ | CDRFEFECHQ | PKKCIPNWKR | CDGHQDCQDG | 
    1550:
    QDEANCPTHS | TLTCTSREFK | CEDGEACIVL | SERCDGFLDC | SDESDEKACS | 
    1600:
    DELTVYKVQN | LQWTADFSGD | VTLTWMRPKK | MPSASCVYNV | YYRVVGESIW | 
    1650:
    KTLETHSNKT | STVLKVLKPD | TTYQVKVQVH | CLNKVHNTND | FVTLRTPEGL | 
    1700:
    PDAPRNLQLS | LNSEEEGVIL | GHWAPPVHTH | GLIREYIVEY | SRSGSKMWAS | 
    1750:
    QRAASNSTEI | KNLLLNALYT | VRVAAVTSRG | IGNWSDSKSI | TTIKGKVIQA | 
    1800:
    PNIHIDSYDE | NSLSFTLTMD | GDIKVNGYVV | NLFWSFDAHK | QEKKTLSFRG | 
    1850:
    GSALSHRVSN | LTAHTSYEIS | AWAKTDLGDS | PLAFEHILTR | GSSPPAPSLK | 
    1900:
    AKAINQTAVE | CIWTGPKNVV | YGIFYATSFL | DLYRNPKSVT | TSLHNKTVIV | 
    1950:
    SKDEQYLFLV | RVLIPYQGPS | SDYVVVKMIP | DSRLPPRHLH | AVHIGKTSAL | 
    2000:
    IKWESPYDSP | DQDLFYAIAV | KDLIRKTDRS | YKVRSRNSTV | EYSLSKLEPG | 
    2050:
    GKYHIIVQLG | NMSKDSSIKI | TTVSLSAPDA | LKIITENDHV | LLFWKSLALK | 
    2100:
    EKQFNETRGY | EIHMSDSAVN | LTAYLGNTTD | NFFKVSNLKM | GHNYTFTVQA | 
    2150:
    RCLFGSQICG | EPAVLLYDEL | SSGADAAVIQ | AARSTDVAAV | VVPILFLILL | 
    2200:
    SLGVGFAILY | TKHRRLQSSF | SAFANSHYSS | RLGSAIFSSG | DDLGEDDEDA | 
    2215:
    PMITGFSDDV | PMVIA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Sortilin-related receptor
    Cat.:
    E5512h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Sortilin-related receptor
    MSDS:
    Please sign in first.
    ELISA Kit for Mouse Sortilin-related receptor
    Cat.:
    E5512m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Sortilin-related receptor
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Sortilin-related receptor
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Sortilin-related receptor
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Sortilin-related receptor
    Cat.:
    U5512h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Sortilin-related receptor
    Cat.:
    U5512m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Sortilin-related receptor
    Cat.:
    P5512Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Sortilin-related receptor
    Cat.:
    P5512Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Sortilin-related receptor
    Polyclonal Antibody for Mouse Sortilin-related receptor
    Monoclonal Antibody for Mouse Sortilin-related receptor
    Monoclonal Antibody for Mouse Sortilin-related receptor
    Monoclonal Antibody for Mouse Sortilin-related receptor
    Monoclonal Antibody for Mouse Sortilin-related receptor
    Protein for Mouse Sortilin-related receptor
    Protein for Mouse Sortilin-related receptor
    Protein for Mouse Sortilin-related receptor
    Protein for Mouse Sortilin-related receptor

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    Precision
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Brain.
    3. 3.
      "Unique expression pattern of a novel mosaic receptor in the developing cerebral cortex."
      Hermans-Borgmeyer I. , Hampe W. , Schinke B. , Methner A. , Nykjaer A. , Suesens U. , Fenger U. , Herbarth B. , Schaller H.C.
      Mech. Dev.70:65-76(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 183-2215
      tissue: Brain.
    4. 4.
      Boehmelt G. , Antonio L. , Iscove N.N.
      Submitted (1997-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1119-1713
      strain: Swiss Webster.
    5. 5.
      "LR11, an LDL receptor gene family member, is a novel regulator of smooth muscle cell migration."
      Zhu Y. , Bujo H. , Yamazaki H. , Ohwaki K. , Jiang M. , Hirayama S. , Kanaki T. , Shibasaki M. , Takahashi K. , Schneider W.J. , Saito Y.
      Circ. Res.94:752-758(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH APP
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