Protein name:
Sortilin-related receptor ;
Alternative:
Low-density lipoprotein receptor relative with 11 ligand-binding repeats (LDLR relative with 11 ligand-binding repeats;LR11) ;Gp250 ;Sorting protein-related receptor containing LDLR class A repeats (mSorLA) ;SorLA-1 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with GGA1 and ROCK2.
Function:
Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. May play a role in neural organization, as well as the establishment of embryonic organ systems.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MATRSSRRES | RLPFLFALVA | LLPRGALGGG | WTQRLHGGPA | PLPQDRGFFV |
100:
VQGDPRDLRL | GTHGDAPGAS | PAARKPLRTR | RSAALQPQPI | QVYGQVSLND |
150:
SHNQMVVHWA | GEKSNVIVAL | ARDSLALARP | KSSDVYVSYD | YGKSFSKISE |
200:
KLNFGVGNNS | EAVISQFYHS | PADNKRYIFV | DAYAQYLWIT | FDFCSTIHGF |
250:
SIPFRAADLL | LHSKASNLLL | GFDRSHPNKQ | LWKSDDFGQT | WIMIQEHVKS |
300:
FSWGIDPYDQ | PNAIYIERHE | PFGFSTVLRS | TDFFQSRENQ | EVILEEVRDF |
350:
QLRDKYMFAT | KVVHLPGSQQ | QSSVQLWVSF | GRKPMRAAQF | VTKHPINEYY |
400:
IADAAEDQVF | VCVSHSNNST | NLYISEAEGL | KFSLSLENVL | YYSPGGAGSD |
450:
TLVRYFANEP | FADFHRVEGL | QGVYIATLIN | GSMNEENMRS | VITFDKGGTW |
500:
EFLQAPAFTG | YGEKINCELS | QGCSLHLAQR | LSQLLNLQLR | RMPILSKESA |
550:
PGLIIATGSV | GKNLASKTNV | YISSSAGARW | REALPGPHYY | TWGDHGGIIM |
600:
AIAQGMETNE | LKYSTNEGET | WKTFVFSEKP | VFVYGLLTEP | GEKSTVFTIF |
650:
GSNKESVHSW | LILQVNATDA | LGVPCTENDY | KLWSPSDERG | NECLLGHKTV |
700:
FKRRTPHATC | FNGEDFDRPV | VVSNCSCTRE | DYECDFGFKM | SEDLSLEVCV |
750:
PDPEFSGKPY | SPPVPCPVGS | SYRRTRGYRK | ISGDTCSGGD | VEARLEGELV |
800:
PCPLAEENEF | ILYAMRKSIY | RYDLASGATE | QLPLSGLRAA | VALDFDYERN |
850:
CLYWSDLALD | TIQRLCLNGS | TGQEVIINSG | LETVEALAFE | PLSQLLYWVD |
900:
AGFKKIEVAN | PDGDFRLTIV | NSSVLDRPRA | LVLVPQEGVM | FWTDWGDLKP |
950:
GIYRSYMDGS | AAYRLVSEDV | KWPNGISVDS | QWIYWTDAYL | DCIERITFSG |
1000:
QQRSVILDSL | PHPYAIAVFK | NEIYWDDWSQ | LSIFRASKHS | RSQVEILASQ |
1050:
LTGLMDMKVF | YKGKNAGSNA | CVPQPCSLLC | LPKANNSKSC | RCPEGVASSV |
1100:
LPSGDLMCDC | PQGYQRKNNT | CVKEENTCLR | NQYRCSNGNC | INSIWWCDFD |
1150:
NDCGDMSDER | NCPTTVCDAD | TQFRCQESGT | CIPLSYKCDL | EDDCGDNSDE |
1200:
SHCEMHQCRS | DEFNCSSGMC | IRSSWVCDGD | NDCRDWSDEA | NCTAIYHTCE |
1250:
ASNFQCHNGH | CIPQRWACDG | DADCQDGSDE | DPVSCEKKCN | GFHCPNGTCI |
1300:
PSSKHCDGLR | DCPDGSDEQH | CEPFCTRFMD | FVCKNRQQCL | FHSMVCDGIV |
1350:
QCRDGSDEDA | AFAGCSQDPE | FHKECDEFGF | QCQNGVCISL | IWKCDGMDDC |
1400:
GDYSDEANCE | NPTEAPNCSR | YFQFHCENGH | CIPNRWKCDR | ENDCGDWSDE |
1450:
KDCGDSHVLP | SPTPGPSTCL | PNYFHCSSGA | CVMGTWVCDG | YRDCADGSDE |
1500:
EACPSLANST | AASTPTQFGQ | CDRFEFECHQ | PKKCIPNWKR | CDGHQDCQDG |
1550:
QDEANCPTHS | TLTCTSREFK | CEDGEACIVL | SERCDGFLDC | SDESDEKACS |
1600:
DELTVYKVQN | LQWTADFSGD | VTLTWMRPKK | MPSASCVYNV | YYRVVGESIW |
1650:
KTLETHSNKT | STVLKVLKPD | TTYQVKVQVH | CLNKVHNTND | FVTLRTPEGL |
1700:
PDAPRNLQLS | LNSEEEGVIL | GHWAPPVHTH | GLIREYIVEY | SRSGSKMWAS |
1750:
QRAASNSTEI | KNLLLNALYT | VRVAAVTSRG | IGNWSDSKSI | TTIKGKVIQA |
1800:
PNIHIDSYDE | NSLSFTLTMD | GDIKVNGYVV | NLFWSFDAHK | QEKKTLSFRG |
1850:
GSALSHRVSN | LTAHTSYEIS | AWAKTDLGDS | PLAFEHILTR | GSSPPAPSLK |
1900:
AKAINQTAVE | CIWTGPKNVV | YGIFYATSFL | DLYRNPKSVT | TSLHNKTVIV |
1950:
SKDEQYLFLV | RVLIPYQGPS | SDYVVVKMIP | DSRLPPRHLH | AVHIGKTSAL |
2000:
IKWESPYDSP | DQDLFYAIAV | KDLIRKTDRS | YKVRSRNSTV | EYSLSKLEPG |
2050:
GKYHIIVQLG | NMSKDSSIKI | TTVSLSAPDA | LKIITENDHV | LLFWKSLALK |
2100:
EKQFNETRGY | EIHMSDSAVN | LTAYLGNTTD | NFFKVSNLKM | GHNYTFTVQA |
2150:
RCLFGSQICG | EPAVLLYDEL | SSGADAAVIQ | AARSTDVAAV | VVPILFLILL |
2200:
SLGVGFAILY | TKHRRLQSSF | SAFANSHYSS | RLGSAIFSSG | DDLGEDDEDA |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Chicken
Mouse
Rabbit
ELISA Kit for Mouse Sortilin-related receptor
ELISA Kit for Mouse Sortilin-related receptor
ELISA Kit for Mouse Sortilin-related receptor
ELISA Kit for Mouse Sortilin-related receptor
CLIA Kit for Mouse Sortilin-related receptor
CLIA Kit for Mouse Sortilin-related receptor
CLIA Kit for Mouse Sortilin-related receptor
CLIA Kit for Mouse Sortilin-related receptor
Polyclonal Antibody for Mouse Sortilin-related receptor
Polyclonal Antibody for Mouse Sortilin-related receptor
Polyclonal Antibody for Mouse Sortilin-related receptor
Polyclonal Antibody for Mouse Sortilin-related receptor
Monoclonal Antibody for Mouse Sortilin-related receptor
Monoclonal Antibody for Mouse Sortilin-related receptor
Monoclonal Antibody for Mouse Sortilin-related receptor
Monoclonal Antibody for Mouse Sortilin-related receptor
Protein for Mouse Sortilin-related receptor
Protein for Mouse Sortilin-related receptor
Protein for Mouse Sortilin-related receptor
Protein for Mouse Sortilin-related receptor
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Brain .
2.
"The transcriptional landscape of the mammalian genome."
Carninci P.
,
Kasukawa T.
,
Katayama S.
,
Gough J.
,
Frith M.C.
,
Maeda N.
,
Oyama R.
,
Ravasi T.
,
Lenhard B.
,
Wells C.
,
Kodzius R.
,
Shimokawa K.
,
Bajic V.B.
,
Brenner S.E.
,
Batalov S.
,
Forrest A.R.
,
Zavolan M.
,
Davis M.J.
,
Wilming L.G.
,
Aidinis V.
,
Allen J.E.
,
Ambesi-Impiombato A.
,
Apweiler R.
,
Aturaliya R.N.
,
Bailey T.L.
,
Bansal M.
,
Baxter L.
,
Beisel K.W.
,
Bersano T.
,
Bono H.
,
Chalk A.M.
,
Chiu K.P.
,
Choudhary V.
,
Christoffels A.
,
Clutterbuck D.R.
,
Crowe M.L.
,
Dalla E.
,
Dalrymple B.P.
,
de Bono B.
,
Della Gatta G.
,
di Bernardo D.
,
Down T.
,
Engstrom P.
,
Fagiolini M.
,
Faulkner G.
,
Fletcher C.F.
,
Fukushima T.
,
Furuno M.
,
Futaki S.
,
Gariboldi M.
,
Georgii-Hemming P.
,
Gingeras T.R.
,
Gojobori T.
,
Green R.E.
,
Gustincich S.
,
Harbers M.
,
Hayashi Y.
,
Hensch T.K.
,
Hirokawa N.
,
Hill D.
,
Huminiecki L.
,
Iacono M.
,
Ikeo K.
,
Iwama A.
,
Ishikawa T.
,
Jakt M.
,
Kanapin A.
,
Katoh M.
,
Kawasawa Y.
,
Kelso J.
,
Kitamura H.
,
Kitano H.
,
Kollias G.
,
Krishnan S.P.
,
Kruger A.
,
Kummerfeld S.K.
,
Kurochkin I.V.
,
Lareau L.F.
,
Lazarevic D.
,
Lipovich L.
,
Liu J.
,
Liuni S.
,
McWilliam S.
,
Madan Babu M.
,
Madera M.
,
Marchionni L.
,
Matsuda H.
,
Matsuzawa S.
,
Miki H.
,
Mignone F.
,
Miyake S.
,
Morris K.
,
Mottagui-Tabar S.
,
Mulder N.
,
Nakano N.
,
Nakauchi H.
,
Ng P.
,
Nilsson R.
,
Nishiguchi S.
,
Nishikawa S.
,
Nori F.
,
Ohara O.
,
Okazaki Y.
,
Orlando V.
,
Pang K.C.
,
Pavan W.J.
,
Pavesi G.
,
Pesole G.
,
Petrovsky N.
,
Piazza S.
,
Reed J.
,
Reid J.F.
,
Ring B.Z.
,
Ringwald M.
,
Rost B.
,
Ruan Y.
,
Salzberg S.L.
,
Sandelin A.
,
Schneider C.
,
Schoenbach C.
,
Sekiguchi K.
,
Semple C.A.
,
Seno S.
,
Sessa L.
,
Sheng Y.
,
Shibata Y.
,
Shimada H.
,
Shimada K.
,
Silva D.
,
Sinclair B.
,
Sperling S.
,
Stupka E.
,
Sugiura K.
,
Sultana R.
,
Takenaka Y.
,
Taki K.
,
Tammoja K.
,
Tan S.L.
,
Tang S.
,
Taylor M.S.
,
Tegner J.
,
Teichmann S.A.
,
Ueda H.R.
,
van Nimwegen E.
,
Verardo R.
,
Wei C.L.
,
Yagi K.
,
Yamanishi H.
,
Zabarovsky E.
,
Zhu S.
,
Zimmer A.
,
Hide W.
,
Bult C.
,
Grimmond S.M.
,
Teasdale R.D.
,
Liu E.T.
,
Brusic V.
,
Quackenbush J.
,
Wahlestedt C.
,
Mattick J.S.
,
Hume D.A.
,
Kai C.
,
Sasaki D.
,
Tomaru Y.
,
Fukuda S.
,
Kanamori-Katayama M.
,
Suzuki M.
,
Aoki J.
,
Arakawa T.
,
Iida J.
,
Imamura K.
,
Itoh M.
,
Kato T.
,
Kawaji H.
,
Kawagashira N.
,
Kawashima T.
,
Kojima M.
,
Kondo S.
,
Konno H.
,
Nakano K.
,
Ninomiya N.
,
Nishio T.
,
Okada M.
,
Plessy C.
,
Shibata K.
,
Shiraki T.
,
Suzuki S.
,
Tagami M.
,
Waki K.
,
Watahiki A.
,
Okamura-Oho Y.
,
Suzuki H.
,
Kawai J.
,
Hayashizaki Y.
more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6 .
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 183-2215
tissue :
Brain .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1119-1713
strain :
Swiss Webster .
5.
"LR11, an LDL receptor gene family member, is a novel regulator of smooth muscle cell migration."
Zhu Y.
,
Bujo H.
,
Yamazaki H.
,
Ohwaki K.
,
Jiang M.
,
Hirayama S.
,
Kanaki T.
,
Shibasaki M.
,
Takahashi K.
,
Schneider W.J.
,
Saito Y.
Circ. Res.94:752-758(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
6.
"Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein."
Andersen O.M.
,
Reiche J.
,
Schmidt V.
,
Gotthardt M.
,
Spoelgen R.
,
Behlke J.
,
von Arnim C.A.
,
Breiderhoff T.
,
Jansen P.
,
Wu X.
,
Bales K.R.
,
Cappai R.
,
Masters C.L.
,
Gliemann J.
,
Mufson E.J.
,
Hyman B.T.
,
Paul S.M.
,
Nykjaer A.
,
Willnow T.E.
more...
Proc. Natl. Acad. Sci. U.S.A.102:13461-13466(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH APP