Gene name:
Serpinb6 (Serpinb6a;Spi3) ;
Protein name:
Serpin B6 ;
Alternative:
Proteinase inhibitor 6 (PI-6) ;Placental thrombin inhibitor ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Forms a complex with the monomeric form of beta-tryptase.
Function:
Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress. May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MDPLQEANGT | FALNLLKILG | EDSSKNVFLS | PMSISSALAM | VFMGAKGTTA |
100:
SQMAQALALD | KCSGNGGGDV | HQGFQSLLTE | VNKTGTQYLL | RTANRLFGDK |
150:
TCDLLASFKD | SCLKFYEAEL | EELDFQGATE | ESRQHINTWV | AKKTEDKIKE |
200:
VLSPGTVNSD | TSLVLVNAIY | FKGNWEKQFN | KEHTREMPFK | VSKNEEKPVQ |
250:
MMFKKSTFKM | TYIGEIFTKI | LLLPYVSSEL | NMIIMLPDEH | VELSTVEKEV |
300:
TYEKFIEWTR | LDKMDEEEVE | VFLPKFKLEE | NYNMNDALYK | LGMTDAFGGR |
350:
ADFSGMSSKQ | GLFLSKVVHK | AFVEVNEEGT | EAAAATAGMM | TVRCMRFTPR |
378:
FCADHPFLFF | IHHVKTNGIL | FCGRFSSP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Mouse
ELISA Kit for Mouse Serpin B6
ELISA Kit for Mouse Serpin B6
ELISA Kit for Mouse Serpin B6
CLIA Kit for Mouse Serpin B6
CLIA Kit for Mouse Serpin B6
CLIA Kit for Mouse Serpin B6
Polyclonal Antibody for Mouse Serpin B6
Polyclonal Antibody for Mouse Serpin B6
Polyclonal Antibody for Mouse Serpin B6
Monoclonal Antibody for Mouse Serpin B6
Monoclonal Antibody for Mouse Serpin B6
Monoclonal Antibody for Mouse Serpin B6
Protein for Mouse Serpin B6
Protein for Mouse Serpin B6
Protein for Mouse Serpin B6
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
BALB/c .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Mammary tumor .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
4.
"A truncating mutation in SERPINB6 is associated with autosomal-recessive nonsyndromic sensorineural hearing loss."
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Am. J. Hum. Genet.86:797-804(2010)
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PubMed ]
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Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
5.
"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J.
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Chen Y.
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Tishkoff D.X.
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Peng C.
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Dai L.
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Mol. Cell50:919-930(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-197;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic fibroblast .