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Index > Protein center > Sphkap(Gene name) > Mouse
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  • Sphkap (Gene name),
  • A-kinase anchor protein SPHKAP (Protein name ),  SPKAP_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Sphkap(Kiaa1678);
    Protein name:
    A-kinase anchor protein SPHKAP;
    Alternative:
    SPHK1-interactor and AKAP domain-containing protein;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts (via the PKA-RII subunit binding domain) with the RI subunit of PKA. Interacts with SPHK1; the interaction greatly reduces SPHK1 activity.
    Function:
    Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1.
    Subcellular Location:
    Cytoplasm Colocalizes with SPHK1 in the cytoplasm.
    Protein Attributes:
    Sequence length:
    1687
    Sequence:
    50:
    MDVNSRLSVQ | SNVESPLMHE | GPEPQQITSS | AAGNLAGSIT | ACKKVLRSNS | 
    100:
    LLESTDYWLQ | NQRTPCQIGF | VEDESENCAS | VCFVNLDVNK | DACITENLQQ | 
    150:
    KLVNVSPDLP | NLISSMNVQQ | PKENEIVLLS | GLASGNPQAD | FDVSQCPWLP | 
    200:
    DICLVQCARG | NRPNSTNCII | FEINKFLIGL | EVVQERQLHL | ETNVLKLEDD | 
    250:
    TNCSLSSIEE | DFLTASEHLE | EEIEVDDCRS | GLENTNVSAN | VLESKKPKET | 
    300:
    TQEGWDYHKE | KLHCALGEKH | IRKHRTPSTK | TEGSKENTEE | NTSLKSLNRL | 
    350:
    VRPSHLKSEV | AGNKQLATNY | SYPENIKGEL | ETSQMLFIPR | DAYLSMVKKD | 
    400:
    VLSPCSVLSE | QGGSHRDHDV | TPNPLPPVQN | GEASTGEYAT | NLAESVMQDA | 
    450:
    FIRLSQSQPT | LPQESAVSFS | MRSALLPSGC | CTKDMVVPRS | WNELPKIVIV | 
    500:
    QSPDGSDTVP | EPNVSSWPDM | EFVETSGIFS | ADSSSRPTQS | ALEVALACAA | 
    550:
    TVIGTISSPQ | ATERFAMEQE | SLVSTYAQRG | TGVQQTQVPQ | AFMAPSTTEY | 
    600:
    SFPSALCGMT | QVASAVAVCG | LCEKEEATCP | VAPTDLLPTS | GASEEISSIG | 
    650:
    SLVMERSTEL | GKEAIAEALL | REATLILARP | DAYSSLGELL | ESVNQRIIET | 
    700:
    TSKTQTLCTE | SVQRNELAHT | LSNVILKHSV | DELHQKTTMA | HPTDERHPCG | 
    750:
    TLDTLMESVN | QLLHNVICFT | FKKMNHIVTL | SEHPSFDQAA | GQAWVKAFAC | 
    800:
    PSSQPLSNAH | GTGLVIRNLV | EDASPKSNKG | GARPELVNNP | RLQSEFSCSH | 
    850:
    RMFDSTAKSF | PKEIYLKGIM | GEDTRNPHHT | LNYDSNERRA | STDLGKLTTA | 
    900:
    SEGCSGFQET | EDSIVPNTQE | KYICATPLNN | EAQVNLSLLG | DDLSVPAQST | 
    950:
    LEAKQSEVYG | ITDFAEELAE | TVVSMATEIA | AICLDNSNGK | QPWFCAWKRG | 
    1000:
    NEFLTAPNGS | CRSLKRKKEN | SSAGSTVRKH | KPPRLSEIKR | KADEHPELKE | 
    1050:
    KLMNRVMDES | MNLEDIPDSV | STFANEVAAK | IMNLTEFSMV | DGVWQGQSCS | 
    1100:
    RTRLLGGDRW | NRLKASSCES | IPEEDSEARV | FVNSLGLMST | LSQPVSRASS | 
    1150:
    VSKQSSCESI | TDEFSRFMVK | QMENEGRGFE | LLLDYYAGKN | ASSIMSSAMQ | 
    1200:
    QACQKNDHLN | VRPSCPSKQS | STESITEEFY | RYMLRDIAKE | SKDGASSRRS | 
    1250:
    SHDWTTGLLS | PSTRSPLCYR | QSSMPDSRSP | CSRLTVNAPV | KANSLDGFAQ | 
    1300:
    NCPQDSVNVQ | PVSRASSSGL | CKSDSCLYRR | SGTDQITNML | IHETWASSIE | 
    1350:
    ALMRKNKIIA | DDSEAANASP | GPVSSGSPLQ | VEKNANRLAT | SKGHRGPTLL | 
    1400:
    VQESVDYQRK | DAVTEGNHSP | VSSPGKTAPV | KKPSDFDPRR | ETSACHNAAG | 
    1450:
    LNSPRRSLCS | RDVPLIQIET | DQKEECIGEP | GPFLSQSGSL | EETEGHQPEE | 
    1500:
    TIPDVARNED | TAPSTCQSSR | DSLETSGEVE | VEVLKEDIPR | DESRNPPSSS | 
    1550:
    EESTGSWSQL | ANEEDIPDDT | SSFLQLSERS | MSNGNSSGTS | SLGIMDLDIY | 
    1600:
    QESIPSSPMI | NELVEEKEIL | KEQSESIKEH | ASGLPGRAAS | PQRSLLVINF | 
    1650:
    DLEPECPDAE | LRATLQWIAA | SELGIPTIYF | KKSQESRIEK | FLDVVKLVQQ | 
    1687:
    KSWKVGDIFH | AVVQYCKLHA | EQKERTPSLF | DWLLELG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse A-kinase anchor protein SPHKAP
    ELISA Kit for Mouse A-kinase anchor protein SPHKAP
    ELISA Kit for Mouse A-kinase anchor protein SPHKAP
    CLIA Kit for Mouse A-kinase anchor protein SPHKAP
    CLIA Kit for Mouse A-kinase anchor protein SPHKAP
    CLIA Kit for Mouse A-kinase anchor protein SPHKAP
    Polyclonal Antibody for Mouse A-kinase anchor protein SPHKAP
    Polyclonal Antibody for Mouse A-kinase anchor protein SPHKAP
    Polyclonal Antibody for Mouse A-kinase anchor protein SPHKAP
    Monoclonal Antibody for Mouse A-kinase anchor protein SPHKAP
    Monoclonal Antibody for Mouse A-kinase anchor protein SPHKAP
    Monoclonal Antibody for Mouse A-kinase anchor protein SPHKAP
    Protein for Mouse A-kinase anchor protein SPHKAP
    Protein for Mouse A-kinase anchor protein SPHKAP
    Protein for Mouse A-kinase anchor protein SPHKAP

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-868 (ISOFORM 3);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 899-1687 (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Diencephalon.
      tissue: Hypothalamus.
      tissue: Testis.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: C57BL/6J.
      tissue: Brain.
      tissue: Embryo.
      tissue: Eye.
    3. 3.
      "Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Aizawa H. , Yuasa S. , Nakajima D. , Nagase T. , Ohara O. , Koga H.
      DNA Res.10:35-48(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 288-1687 (ISOFORM 1)
    4. 4.
      "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
      Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
      Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
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