Protein name:
SPRY domain-containing SOCS box protein 1 (SSB-1) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Component of the probable ECS(SPSB1) E3 ubiquitin-protein ligase complex which contains CUL5, RNF7/RBX2, Elongin BC complex and SPSB1. Interacts with CUL5, RNF7, TCEB1 and TCEB2 (By similarity). Interacts with PARW. Directly interacts with MET tyrosine kinase domain in the presence and in the absence of HGF, however HGF treatment has a positive effect on this interaction. When phosphorylated, interacts with RASA1 without affecting its stability.
Function:
Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MGQKVTGGIK | TVDMRDPTYR | PLKQELQGLD | YCKPTRLDLL | LDMPPVSYDV |
100:
QLLHSWNNND | RSLNVFVKED | DKLIFHRHPV | AQSTDAIRGK | VGYTRGLHVW |
150:
QITWAMRQRG | THAVVGVATA | DAPLHSVGYT | TLVGNNHESW | GWDLGRNRLY |
200:
HDGKNQPSKT | YPAFLEPDET | FIVPDSFLVA | LDMDDGTLSF | IVDGQYMGVA |
250:
FRGLKGKKLY | PVVSAVWGHC | EIRMRYLNGL | DPEPLPLMDL | CRRSVRLALG |
273:
KERLGAIPAL | PLPASLKAYL | LYQ
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Mouse
Human
ELISA Kit for Mouse SSB-1
ELISA Kit for Mouse SSB-1
ELISA Kit for Mouse SSB-1
Polyclonal Antibody for Mouse SSB-1
Polyclonal Antibody for Mouse SSB-1
Polyclonal Antibody for Mouse SSB-1
Monoclonal Antibody for Mouse SSB-1
Monoclonal Antibody for Mouse SSB-1
Monoclonal Antibody for Mouse SSB-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.
"The transcriptional landscape of the mammalian genome."
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
C57BL/6J .
strain :
NOD .
tissue :
Aorta .
tissue :
Embryo .
tissue :
Pituitary anterior lobe .
tissue :
Spleen .
tissue :
Testis .
tissue :
Vein .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
strain :
C57BL/6 .
tissue :
Eye .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH PAWR AND MET
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH ELONGIN BC COMPLEX