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Index > Protein center > Sms(Gene name) > Mouse
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  • Sms (Gene name),
  • Spermine synthase (Protein name ),  SPSY_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Sms;
    Protein name:
    Spermine synthase(SPMSY);
    Alternative:
    Spermidine aminopropyltransferase;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer. Dimerization is mediated through the N-terminal domain and seems to be required for activity as deletion of the N-terminal domain causes complete loss of activity.
    Function:
    Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM) (By similarity). Required for normal viability, growth and fertility.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    366
    Sequence:
    50:
    MAAARHSTLD | FKLGAKADGE | AILKGLQSIF | QEQGMTESVH | TWQDHGYLAT | 
    100:
    YTNKNGSFAN | LRIYPHGLVL | LDLQSYDSDV | QGKQETDSLL | NKIEEKMKEL | 
    150:
    SQDSTGRVKR | LPPIVRGGAI | DRYWPTADGR | LVEYDIDEVV | YDEDSPYQNI | 
    200:
    KILHSKQFGN | ILILSGDVNL | AESDLAYTRA | IMGSGKEDYT | GKDVLILGGG | 
    250:
    DGGILCEIVK | LKPKMVTMVE | IDQMVIDGCK | KYMRRTCGDV | LDNLRGDCYQ | 
    300:
    VLIEDCIPVL | KMYAKEGREF | DYVINDLTAV | PISTSPEEDS | TWDFLRLILD | 
    350:
    LSMKVLKQDG | KYFTQGNCVN | LTEALSLYEE | QLGRLYCPVE | FSKEIVCVPS | 
    366:
    YLELWVFYTV | WKKAKP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse SPMSY
    Cat.:
    E15228h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse SPMSY
    Cat.:
    E15228b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse SPMSY
    Cat.:
    E15228m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse SPMSY
    Cat.:
    U15228b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse SPMSY
    Cat.:
    U15228h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse SPMSY
    Cat.:
    U15228m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse SPMSY
    Cat.:
    P15228Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse SPMSY
    Polyclonal Antibody for Mouse SPMSY
    Cat.:
    P15228Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse SPMSY
    Monoclonal Antibody for Mouse SPMSY
    Monoclonal Antibody for Mouse SPMSY
    Protein for Mouse SPMSY
    Protein for Mouse SPMSY
    Protein for Mouse SPMSY

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Pex gene deletions in Gy and Hyp mice provide mouse models for X-linked hypophosphatemia."
      Strom T.M. , Francis F. , Lorenz B. , Boeddrich A. , Econs M.J. , Lehrach H. , Meitinger T.
      Hum. Mol. Genet.6:165-171(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Nucleotide sequence of mouse spermidine aminopropyltransferase cDNA."
      Niiranen K. , Korhonen V. , Janne J.
      Submitted (1997-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Diaphragm.
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Bone marrow macrophage.
      tissue: Embryo.
      tissue: Embryonic spinal cord.
      tissue: Morula.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Brain.
      tissue: Olfactory epithelium.
    6. 6.
      "Spermine deficiency resulting from targeted disruption of the spermine synthase gene in embryonic stem cells leads to enhanced sensitivity to antiproliferative drugs."
      Korhonen V.-P. , Niiranen K. , Halmekyto M. , Pietila M. , Diegelman P. , Parkkinen J.J. , Eloranta T. , Porter C.W. , Alhonen L. , Janne J.
      Mol. Pharmacol.59:231-238(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 58-315
      strain: 129/SvJ.
    7. 7.
      Lubec G. , Sunyer B. , Chen W.-Q.
      Submitted (2009-01) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 297-307;IDENTIFICATION BY MASS SPECTROMETRY
      strain: OF1.
      tissue: Hippocampus.
    8. 8.
      "Spermine deficiency in Gy mice caused by deletion of the spermine synthase gene."
      Lorenz B. , Francis F. , Gempel K. , Boeddrich A. , Josten M. , Schmahl W. , Schmidt J. , Lehrach H. , Meitinger T. , Strom T.M.
      Hum. Mol. Genet.7:541-547(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 316-366;DISRUPTION PHENOTYPE
    9. 9.
      "Spermine synthesis is required for normal viability, growth, and fertility in the mouse."
      Wang X. , Ikeguchi Y. , McCloskey D.E. , Nelson P. , Pegg A.E.
      J. Biol. Chem.279:51370-51375(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
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