Sptlc2 ELISA Kit for Mouse(Mus musculus) | EIAab.comSptlc2 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Sptlc2(Gene name) > Mouse

Sptlc2 (Gene name),

Serine palmitoyltransferase 2 (Protein name ), SPTC2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Sptlc2(Lcb2);

Protein name:

Serine palmitoyltransferase 2;

Alternative:

Long chain base biosynthesis protein 2a(LCB2a);Long chain base biosynthesis protein 2(LCB 2);Serine-palmitoyl-CoA transferase 2(SPT 2);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Heterodimer with SPTLC1. Component of the serine palmitoyltransferase (SPT) complex, composed of LCB1/SPTLC1, LCB2 (SPTLC2 or SPTLC3) and ssPT (SSSPTA or SSSPTB).

Function:

Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SSSPTA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SSSPTB complex displays a preference for C18-CoA substrate.

Subcellular Location:

Endoplasmic reticulum membrane Single-pass membrane protein

Protein Attributes:

Sequence length:

560

Sequence:

50:

100:

150:

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250:

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350:

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450:

500:

550:

560:

DETTYEETED |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P97363

Pfam:

PF00155

KEGG:

mmu:20773

UniGene:

Mm.565

SMR:

P97363

Uniprot:

P97363

FOR

ELISA Kit for Mouse Serine palmitoyltransferase 2

CLIA Kit for Mouse Serine palmitoyltransferase 2

Polyclonal Antibody for Mouse Serine palmitoyltransferase 2

Monoclonal Antibody for Mouse Serine palmitoyltransferase 2

Protein for Mouse Serine palmitoyltransferase 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Sphingolipid synthesis: identification and characterization of mammalian cDNAs encoding the Lcb2 subunit of serine palmitoyltransferase."
Nagiec M.M. , Lester R.L. , Dickson R.C.
Gene177:237-241(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Kidney.
tissue: Testis.
2.

Nagiec M.M. , Lester R.L. , Dickson R.C.
Submitted (1997-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Human and murine serine-palmitoyl-CoA transferase. Cloning, expression and characterization of the key enzyme in sphingolipid synthesis."
Weiss B. , Stoffel W.
Eur. J. Biochem.249:239-247(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: BALB/c.
tissue: Kidney.
tissue: Liver.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6J.
tissue: Mammary gland.
5.

"Subcellular localization and membrane topology of serine palmitoyltransferase, 3-dehydrosphinganine reductase, and sphinganine N-acyltransferase in mouse liver."
Mandon E.C. , Ehses I. , Rother J. , van Echten G. , Sandhoff K.
J. Biol. Chem.267:11144-11148(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
tissue: Liver.

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