Protein name:
Serum response factor (SRF) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Binds DNA as a multimer, probably a dimer. Interacts with MLLT7/FOXO4, NKX3A and SSRP1 (By similarity). Interacts with ARID2 and SRFBP1. Forms complexes with ARID2, MYOCD, NKX2-5 and SRFBP1. Forms a nuclear ternary complex with MKL1 and SCAI.
Function:
SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS) (By similarity). Required for cardiac differentiation and maturation.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MLPSQAGAAA | ALGRGSALGG | NLNRTPTGRP | GGGGGTRGAN | GGRVPGNGAG |
100:
LGQSRLEREA | AAAAAPTAGA | LYSGSEGDSE | SGEEEELGAE | RRGLKRSLSE |
150:
MELGVVVGGP | EAAAAAAGGY | GPVSGAVSGA | KPGKKTRGRV | KIKMEFIDNK |
200:
LRRYTTFSKR | KTGIMKKAYE | LSTLTGTQVL | LLVASETGHV | YTFATRKLQP |
250:
MITSETGKAL | IQTCLNSPDS | PPRSDPTTDQ | RMSATGFEEP | DLTYQVSESD |
300:
SSGETKDTLK | PAFTVTNLPG | TTSTIQTAPS | TSTTMQVSSG | PSFPITNYLA |
350:
PVSASVSPSA | VSSANGTVLK | STGSGPVSSG | GLMQLPTSFT | LMPGGAVAQQ |
400:
VPVQAIHVHQ | APQQASPSRD | SSTDLTQTSS | SGTVTLPATI | MTSSVPTTVG |
450:
GHMMYPSPHA | VMYAPTSGLA | DGSLTVLNAF | SQAPSTMQVS | HSQVQEPGGV |
500:
PQVFLTAPSG | TVQIPVSAVQ | LHQMAVIGQQ | AGSSSNLTEL | QVVNLDATHS |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Chicken
Mouse
Polyclonal Antibody for Mouse SRF
Polyclonal Antibody for Mouse SRF
Polyclonal Antibody for Mouse SRF
Monoclonal Antibody for Mouse SRF
Monoclonal Antibody for Mouse SRF
Monoclonal Antibody for Mouse SRF
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Serum response factor."
Miwa T.
Submitted (2000-02) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6 .
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH SRFBP1;SUBUNIT
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISRUPTION PHENOTYPE
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH ARID2;SUBUNIT
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-220;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-220;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic fibroblast .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH MKL1 AND SCAI;SUBCELLULAR LOCATION