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Index > Protein center > SRP54(Gene name) > Human
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  • SRP54 (Gene name),
  • Signal recognition particle 54 kDa protein (Protein name ),  SRP54_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    SRP54;
    Protein name:
    Signal recognition particle 54 kDa protein(SRP54);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Signal recognition particle consists of a 7S RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9. Interacts with RNPS1.
    Function:
    Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein).
    Subcellular Location:
    Nucleus speckle Cytoplasm
    Protein Attributes:
    Sequence length:
    504
    Sequence:
    50:
    MVLADLGRKI | TSALRSLSNA | TIINEEVLNA | MLKEVCTALL | EADVNIKLVK | 
    100:
    QLRENVKSAI | DLEEMASGLN | KRKMIQHAVF | KELVKLVDPG | VKAWTPTKGK | 
    150:
    QNVIMFVGLQ | GSGKTTTCSK | LAYYYQRKGW | KTCLICADTF | RAGAFDQLKQ | 
    200:
    NATKARIPFY | GSYTEMDPVI | IASEGVEKFK | NENFEIIIVD | TSGRHKQEDS | 
    250:
    LFEEMLQVAN | AIQPDNIVYV | MDASIGQACE | AQAKAFKDKV | DVASVIVTKL | 
    300:
    DGHAKGGGAL | SAVAATKSPI | IFIGTGEHID | DFEPFKTQPF | ISKLLGMGDI | 
    350:
    EGLIDKVNEL | KLDDNEALIE | KLKHGQFTLR | DMYEQFQNIM | KMGPFSQILG | 
    400:
    MIPGFGTDFM | SKGNEQESMA | RLKKLMTIMD | SMNDQELDST | DGAKVFSKQP | 
    450:
    GRIQRVARGS | GVSTRDVQEL | LTQYTKFAQM | VKKMGGIKGL | FKGGDMSKNV | 
    500:
    SQSQMAKLNQ | QMAKMMDPRV | LHHMGGMAGL | QSMMRQFQQG | AAGNMKGMMG | 
    504:
    FNNM
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    KEGG:
    Pfam:
    UniGene:
    MIM:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human SRP54
    Cat.:
    E11785h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human SRP54
    Cat.:
    E11785r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human SRP54
    Cat.:
    E11785b
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human SRP54
    Cat.:
    E11785m
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    MSDS:
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    96T
    ELISA Kit for Human SRP54
    Cat.:
    E11785d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human SRP54
    Cat.:
    U11785d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human SRP54
    Cat.:
    U11785m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human SRP54
    Cat.:
    U11785r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human SRP54
    Cat.:
    U11785h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human SRP54
    Cat.:
    U11785b
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human SRP54
    Cat.:
    P11785Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human SRP54
    Polyclonal Antibody for Human SRP54
    Cat.:
    P11785Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human SRP54
    Polyclonal Antibody for Human SRP54
    Cat.:
    P11785Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human SRP54
    Monoclonal Antibody for Human SRP54
    Monoclonal Antibody for Human SRP54
    Monoclonal Antibody for Human SRP54
    Monoclonal Antibody for Human SRP54
    Protein for Human SRP54
    Protein for Human SRP54
    Protein for Human SRP54
    Protein for Human SRP54
    Protein for Human SRP54

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Sequence of the highly conserved gene encoding the human 54kDa subunit of signal recognition particle."
      Patel S. , Austen B.
      DNA Seq.6:167-170(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Placenta.
    2. 2.
      "Protein SRP54 of human signal recognition particle: cloning, expression, and comparative analysis of functional sites."
      Gowda K. , Black S.D. , Moeller I. , Sakakibara Y. , Liu M.C. , Zwieb C.
      Gene207:197-207(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Trachea.
    4. 4.
      "The DNA sequence and analysis of human chromosome 14."
      Heilig R. , Eckenberg R. , Petit J.-L. , Fonknechten N. , Da Silva C. , Cattolico L. , Levy M. , Barbe V. , De Berardinis V. , Ureta-Vidal A. , Pelletier E. , Vico V. , Anthouard V. , Rowen L. , Madan A. , Qin S. , Sun H. , Du H. , more...
      Nature421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Eye.
      tissue: Placenta.
    6. 6.
      "Human RNPS1 and its associated factors: a versatile alternative pre-mRNA splicing regulator in vivo."
      Sakashita E. , Tatsumi S. , Werner D. , Endo H. , Mayeda A.
      Mol. Cell. Biol.24:1174-1187(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RNPS1;SUBCELLULAR LOCATION
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      "Crystal structure of the conserved subdomain of human protein SRP54M at 2.1 A resolution: evidence for the mechanism of signal peptide binding."
      Clemons W.M. Jr. , Gowda K. , Black S.D. , Zwieb C. , Ramakrishnan V.
      J. Mol. Biol.292:697-705(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 326-432
    10. 10.
      "Induced structural changes of 7SL RNA during the assembly of human signal recognition particle."
      Kuglstatter A. , Oubridge C. , Nagai K.
      Nat. Struct. Biol.9:740-744(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.1 ANGSTROMS) OF 323-441 IN COMPLEX WITH SRP19 AND 7SL RNA
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