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Index > Protein center > SRP72(Gene name) > Human
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  • SRP72 (Gene name),
  • Signal recognition particle 72 kDa protein (Protein name ),  SRP72_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    SRP72;
    Protein name:
    Signal recognition particle 72 kDa protein(SRP72);
    Alternative:
    Signal recognition particle 72 kDa protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Signal recognition particle consists of a 7S RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.
    Function:
    Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    671
    Sequence:
    50:
    MASGGSGGVS | VPALWSEVNR | YGQNGDFTRA | LKTVNKILQI | NKDDVTALHC | 
    100:
    KVVCLIQNGS | FKEALNVINT | HTKVLANNSL | SFEKAYCEYR | LNRIENALKT | 
    150:
    IESANQQTDK | LKELYGQVLY | RLERYDECLA | VYRDLVRNSQ | DDYDEERKTN | 
    200:
    LSAVVAAQSN | WEKVVPENLG | LQEGTHELCY | NTACALIGQG | QLNQAMKILQ | 
    250:
    KAEDLCRRSL | SEDTDGTEED | PQAELAIIHG | QMAYILQLQG | RTEEALQLYN | 
    300:
    QIIKLKPTDV | GLLAVIANNI | ITINKDQNVF | DSKKKVKLTN | AEGVEFKLSK | 
    350:
    KQLQAIEFNK | ALLAMYTNQA | EQCRKISASL | QSQSPEHLLP | VLIQAAQLCR | 
    400:
    EKQHTKAIEL | LQEFSDQHPE | NAAEIKLTMA | QLKISQGNIS | KACLILRSIE | 
    450:
    ELKHKPGMVS | ALVTMYSHEE | DIDSAIEVFT | QAIQWYQNHQ | PKSPAHLSLI | 
    500:
    REAANFKLKY | GRKKEAISDL | QQLWKQNPKD | IHTLAQLISA | YSLVDPEKAK | 
    550:
    ALSKHLPSSD | SMSLKVDVEA | LENSAGATYI | RKKGGKVTGD | SQPKEQGQGD | 
    600:
    LKKKKKKKKG | KLPKNYDPKV | TPDPERWLPM | RERSYYRGRK | KGKKKDQIGK | 
    650:
    GTQGATAGAS | SELDASKTVS | SPPTSPRPGS | AATVSASTSN | IIPPRHQKPA | 
    671:
    GAPATKKKQQ | QKKKKGGKGG | W
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    Pfam:
    KEGG:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human SRP72
    ELISA Kit for Human SRP72
    CLIA Kit for Human SRP72
    CLIA Kit for Human SRP72
    Polyclonal Antibody for Human SRP72
    Polyclonal Antibody for Human SRP72
    Monoclonal Antibody for Human SRP72
    Monoclonal Antibody for Human SRP72
    Protein for Human SRP72
    Protein for Human SRP72

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Protein SRP72 sequence of human signal recognition particle."
      Gowda K. , Zwieb C.
      Submitted (1998-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Sequence of human signal recognition particle (SRP) 72."
      Utz P.J. , Hottelet M. , Miller I.J. , Anderson P.
      Submitted (1998-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Esophageal carcinoma.
    4. 4.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      Bienvenut W.V. , Waridel P. , Quadroni M.
      Submitted (2009-03) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-20; 63-84; 113-121; 148-163; 242-275; 288-297; 302-324; 326-350; 357-376; 465-475; 480-498; 516-531 AND 601-617;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Cervix carcinoma.
    7. 7.
      "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
      Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-571;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-618;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-618;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 12.
      "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
      Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 14.
      "Exome sequencing identifies autosomal-dominant SRP72 mutations associated with familial aplasia and myelodysplasia."
      Kirwan M. , Walne A.J. , Plagnol V. , Velangi M. , Ho A. , Hossain U. , Vulliamy T. , Dokal I.
      Am. J. Hum. Genet.90:888-892(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT BMFS1 HIS-207;SUBCELLULAR LOCATION;CHARACTERIZATION OF VARIANT BMFS1 HIS-207
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