SRSF4 ELISA Kit for Human(Homo sapiens) | EIAab.comSRSF4 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > SRSF4(Gene name) > Human

SRSF4 (Gene name),

Serine/arginine-rich splicing factor 4 (Protein name ), SRSF4_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

SRSF4(SFRS4;SRP75);

Protein name:

Serine/arginine-rich splicing factor 4;

Alternative:

SRP001LB;Pre-mRNA-splicing factor SRP75;Splicing factor, arginine/serine-rich 4;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Found in a pre-mRNA splicing complex with SRSF4/SFRS4, SRSF5/SFRS5, SNRNP70, SNRPA1, SRRM1 and SRRM2. Interacts with PNN.

Function:

Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10.

Subcellular Location:

Nucleus speckle

Protein Attributes:

Sequence length:

494

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

494:

KPNLPSESRS | RSKSASKTRS | RSKSRSRSAS | RSPSRSRSRS | HSRS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q08170

UniGene:

Hs.469970

String:

Q08170

MIM:

601940

KEGG:

hsa:6429

Pfam:

PF00076

Uniprot:

Q08170

FOR

ELISA Kit for Human Serine/arginine-rich splicing factor 4

CLIA Kit for Human Serine/arginine-rich splicing factor 4

Polyclonal Antibody for Human Serine/arginine-rich splicing factor 4

Monoclonal Antibody for Human Serine/arginine-rich splicing factor 4

Protein for Human Serine/arginine-rich splicing factor 4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Human SR proteins and isolation of a cDNA encoding SRp75."
Zahler A.M. , Neugebauer K.M. , Stolk J.A. , Roth M.B.
Mol. Cell. Biol.13:4023-4028(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE;VARIANTS ASP-253; ALA-338 AND SER-356
2.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
3.

"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lymph.
5.

"Sequencing of human chromosome 1."
Connolly K.S. , Gunning K.M. , Davis C.A. , Kadner K. , Subramanian S. , Miguel T. , Lewis K.D. , Fridlyand J. , Alcivare D. , Benke J.A. , Bondoc M. , Bowen E. , Chiang A. , Critz P. , Jaklevic M.A. , Lindo K. , Lindquist K. , Miller C. , more...
Submitted (1998-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-192
6.

"SR proteins: a conserved family of pre-mRNA splicing factors."
Zahler A.M. , Lane W.S. , Stolk J.A. , Roth M.B.
Genes Dev.6:837-847(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 35-45; 84-89; 126-137; 140-154 AND 172-179
7.

"A coactivator of pre-mRNA splicing."
Blencowe B.J. , Issner R. , Nickerson J.A. , Sharp P.A.
Genes Dev.12:996-1009(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A MRNA SPLICING COMPLEX WITH SRSF5; SNRNP70; SNRPA1; SRRM1 AND SRRM2
8.

"Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors."
Wang J. , Gao Q.S. , Wang Y. , Lafyatis R. , Stamm S. , Andreadis A.
J. Neurochem.88:1078-1090(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
9.

"Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells."
Zimowska G. , Shi J. , Munguba G. , Jackson M.R. , Alpatov R. , Simmons M.N. , Shi Y. , Sugrue S.P.
Invest. Ophthalmol. Vis. Sci.44:4715-4723(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PNN;SUBCELLULAR LOCATION
10.

"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
11.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-78 AND SER-431;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
12.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-431;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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