SULT1A1 ELISA Kit for Human(Homo sapiens) | EIAab.comSULT1A1 ELISA Kit for Human(Homo sapiens)

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SULT1A1 (Gene name),

Sulfotransferase 1A1 (Protein name ), ST1A1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

SULT1A1(OK/SW-cl.88;STP;STP1);

Protein name:

Sulfotransferase 1A1(ST1A1);

Alternative:

HAST1/HAST2;Aryl sulfotransferase 1;Phenol-sulfating phenol sulfotransferase 1(P-PST 1);Phenol sulfotransferase 1;Thermostable phenol sulfotransferase(Ts-PST);ST1A3;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer.

Function:

Catalyzes the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Is also responsible for the sulfation and activation of minoxidil. Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

295

Sequence:

50:

100:

150:

200:

250:

295:

SISPFMRKGM | AGDWKTTFTV | AQNERFDADY | AEKMAGCSLS | FRSEL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000321988

KEGG:

hsa:6817

UniGene:

Hs.567342

Pfam:

PF00685

SMR:

P50225

String:

P50225

MIM:

171150

Uniprot:

P50225

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ELISA Kit for Human ST1A1

Cat.:

E14887h

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96T

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ELISA Kit for Human ST1A1

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ELISA Kit for Human ST1A1

MSDS:

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ELISA Kit for Human ST1A1

Cat.:

E14887m

Price:

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Packing:

96T

ELISA Kit for Human ST1A1

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CLIA Kit for Human ST1A1

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CLIA Kit for Human ST1A1

Cat.:

U14887m

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Packing:

96T

CLIA Kit for Human ST1A1

MSDS:

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CLIA Kit for Human ST1A1

MSDS:

Please sign in first.

CLIA Kit for Human ST1A1

Cat.:

U14887h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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Polyclonal Antibody for Human ST1A1

Monoclonal Antibody for Human ST1A1

Protein for Human ST1A1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Identification of two human brain aryl sulfotransferase cDNAs."
Zhu X. , Veronese M.E. , Bernard C.C. , Sansom L.N. , McManus M.E.
Biochem. Biophys. Res. Commun.195:120-127(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT MET-223
tissue: Brain.
2.

"Molecular characterisation of a human aryl sulfotransferase cDNA."
Zhu X. , Veronese M.E. , Sansom L.N. , McManus M.E.
Biochem. Biophys. Res. Commun.192:671-676(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT MET-223
tissue: Liver.
3.

"Sequence analysis and expression of the cDNA for the phenol-sulfating form of human liver phenol sulfotransferase."
Wilborn T.W. , Comer K.A. , Dooley T.P. , Reardon I.M. , Heinrikson R.L. , Falany C.N.
Mol. Pharmacol.43:70-77(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PARTIAL PROTEIN SEQUENCE;VARIANTS MET-223 AND LYS-282
tissue: Liver.
4.

"Structural similarity and diversity of sulfotransferases."
Yamazoe Y. , Nagata K. , Ozawa S. , Kato R.
Chem. Biol. Interact.92:107-117(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT MET-223
5.

"Molecular cloning of an isoform of phenol sulfotransferase from human brain hippocampus."
Hwang S.-R. , Kohn A.B. , Hook V.Y.H.
Biochem. Biophys. Res. Commun.207:701-707(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT MET-223
tissue: Hippocampus.
6.

"Human platelet phenolsulfotransferases: cDNA cloning, stable expression in V79 cells and identification of a novel allelic variant of the phenol-sulfating form."
Jones A.L. , Hagen M. , Coughtrie M.W.H. , Roberts R.C. , Glatt H.
Biochem. Biophys. Res. Commun.208:855-862(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT MET-223
tissue: Blood.
7.

"Primary structures and properties of two related forms of aryl sulfotransferases in human liver."
Ozawa S. , Nagata K. , Shimada M. , Ueda M. , Tsuzuki T. , Yamazoe Y. , Kato R.
Pharmacogenetics5:S135-S140(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT MET-223
tissue: Liver.
8.

"Genomic organization and DNA sequences of two human phenol sulfotransferase genes (STP1 and STP2) on the short arm of chromosome 16."
Dooley T.P. , Huang Z.
Biochem. Biophys. Res. Commun.228:134-140(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1);VARIANT MET-223
9.

"Human phenol sulfotransferase gene contains two alternative promoters: structure and expression of the gene."
Bernier F. , Soucy P. , Luu-The V.
DNA Cell Biol.15:367-375(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1);VARIANTS MET-223 AND LYS-282
10.

"A single amino acid, Glu146, governs the substrate specificity of a human dopamine sulfotransferase, SULT1A3."
Dajani R. , Hood A.M. , Coughtrie M.W.
Mol. Pharmacol.54:942-948(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT MET-223
tissue: Liver.
11.

Raftogianis R.B. , Her C. , Weinshilboum R.M.
Submitted (1997-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1);VARIANT MET-223
12.

"Identification of immuno-peptidmics that are recognized by tumor-reactive CTL generated from TIL of colon cancer patients."
Shichijo S. , Itoh K.
Submitted (2001-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS HIS-213 AND MET-223
tissue: Colon adenocarcinoma.
13.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT HIS-213
14.

"Full-length cDNA libraries and normalization."
Li W.B. , Gruber C. , Jessee J. , Polayes D.
Submitted (2004-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
15.

"The sequence and analysis of duplication-rich human chromosome 16."
Martin J. , Han C. , Gordon L.A. , Terry A. , Prabhakar S. , She X. , Xie G. , Hellsten U. , Chan Y.M. , Altherr M. , Couronne O. , Aerts A. , Bajorek E. , Black S. , Blumer H. , Branscomb E. , Brown N.C. , Bruno W.J. , more...
Nature432:988-994(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
16.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT MET-223
tissue: Colon.
tissue: Placenta.
17.

"Mapping of the phenol sulfotransferase gene (STP) to human chromosome 16p12.1-p11.2 and to mouse chromosome 7."
Dooley T.P. , Obermoeller R.D. , Leiter E.H. , Chapman H.D. , Falany C.N. , Deng Z. , Siciliano M.J.
Genomics18:440-443(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-107 (ISOFORM 1)
18.

"Functional characterization of two human sulphotransferase cDNAs that encode monoamine- and phenol-sulphating forms of phenol sulphotransferase: substrate kinetics, thermal-stability and inhibitor-sensitivity studies."
Veronese M.E. , Burgess W. , Zhu X. , McManus M.E.
Biochem. J.302:497-502(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
19.

"Characterization of expressed human phenol-sulfating phenol sulfotransferase: effect of mutating cys70 on activity and thermostability."
Falany C.N. , Zhuang W. , Falany J.L.
Chem. Biol. Interact.92:57-66(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF CYS-70
20.

"Structure of a human carcinogen-converting enzyme, SULT1A1. Structural and kinetic implications of substrate inhibition."
Gamage N.U. , Duggleby R.G. , Barnett A.C. , Tresillian M. , Latham C.F. , Liyou N.E. , McManus M.E. , Martin J.L.
J. Biol. Chem.278:7655-7662(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) IN COMPLEX WITH ADENOSINE-3'-5'-DIPHOSPHATE (PAP) AND P-NITROPHENOL;CATALYTIC ACTIVITY;FUNCTION
21.

"The structure of human SULT1A1 crystallized with estradiol. An insight into active site plasticity and substrate inhibition with multi-ring substrates."
Gamage N.U. , Tsvetanov S. , Duggleby R.G. , McManus M.E. , Martin J.L.
J. Biol. Chem.280:41482-41486(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) IN COMPLEX WITH ADENOSINE-3'-5'-DIPHOSPHATE AND ESTRADIOL;CATALYTIC ACTIVITY;FUNCTION
22.

"Crystal structures of SULT1A2 and SULT1A1 *3: insights into the substrate inhibition and the role of Tyr149 in SULT1A2."
Lu J. , Li H. , Zhang J. , Li M. , Liu M.Y. , An X. , Liu M.C. , Chang W.
Biochem. Biophys. Res. Commun.396:429-434(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) IN COMPLEX WITH ADENOSINE-3'-5'-DIPHOSPHATE
23.

"Directed evolution of sulfotransferases and paraoxonases by ancestral libraries."
Alcolombri U. , Elias M. , Tawfik D.S.
J. Mol. Biol.411:837-853(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) IN COMPLEXES WITH ADENOSINE-3'-5'-DIPHOSPHATE AND P-NITROPHENOL;CATALYTIC ACTIVITY
24.

"The molecular basis for the broad substrate specificity of human sulfotransferase 1A1."
Berger I. , Guttman C. , Amar D. , Zarivach R. , Aharoni A.
PLoS ONE6:E26794-E26794(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) IN COMPLEXES WITH ADENOSINE-3'-5'-DIPHOSPHATE AND P-NITROPHENOL;CATALYTIC ACTIVITY
25.

"Phenol sulfotransferase pharmacogenetics in humans: association of common SULT1A1 alleles with TS PST phenotype."
Raftogianis R.B. , Wood T.C. , Otterness D.M. , Van Loon J.A. , Weinshilboum R.M.
Biochem. Biophys. Res. Commun.239:298-304(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS GLN-37; HIS-213 AND MET-223
26.

"Association between functional genetic polymorphisms of human sulfotransferases 1A1 and 1A2."
Engelke C.E. , Meinl W. , Boeing H. , Glatt H.
Pharmacogenetics10:163-169(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HIS-213
27.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] MET-223;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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