STAT1 ELISA Kit for Human(Homo sapiens) | EIAab.comSTAT1 ELISA Kit for Human(Homo sapiens)

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STAT1 (Gene name),

Signal transducer and activator of transcription 1-alpha/beta (Protein name ), STAT1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

STAT1;

Protein name:

Signal transducer and activator of transcription 1-alpha/beta;

Alternative:

Transcription factor ISGF-3 components p91/p84;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Isoform alpha homodimerizes upon IFN-gamma induced phosphorylation. Heterodimer with STAT2 upon IFN-alpha/beta induced phosphorylation. Interacts with NMI. Interacts with Sendai virus C', C, Y1 and Y2 proteins, Nipah virus P, V and W proteins, and rabies virus phosphoprotein preventing activation of ISRE and GAS promoter (By similarity). Interacts with HCV core protein; the interaction results in STAT1 degradation. Interacts with PIAS1; the interaction requires phosphorylation on Ser-727 and inhibits STAT1 activation. Interacts with IFNAR1; the interaction requires the phosphorylation of IFNAR1 at 'Tyr-466'. Interacts with IFNAR2. Interacts with PIAS1 (dimethylated on arginine); the interaction results in release of STAT1 from its target gene.

Function:

Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine-and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. Becomes activated in response to KITLG/SCF and KIT signaling. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.

Subcellular Location:

Cytoplasm Nucleus Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to IFN-gamma and signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4.

Protein Attributes:

Sequence length:

750

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P42224

KEGG:

hsa:6772

UniGene:

Hs.642990

Pfam:

PF00017

STRING:

9606.ENSP00000354394

String:

P42224

MIM:

209950

Uniprot:

P42224

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ELISA Kit for Human Signal transducer and activator of transcription 1-alpha/beta

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E1740h

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ELISA Kit for Human Signal transducer and activator of transcription 1-alpha/beta

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E1740p

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96T

ELISA Kit for Human Signal transducer and activator of transcription 1-alpha/beta

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E1740m

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96T

CLIA Kit for Human Signal transducer and activator of transcription 1-alpha/beta

Cat.:

U1740m

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MSDS:

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Packing:

96T

CLIA Kit for Human Signal transducer and activator of transcription 1-alpha/beta

Cat.:

U1740p

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Signal transducer and activator of transcription 1-alpha/beta

Cat.:

U1740h

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96T

Polyclonal Antibody for Human Signal transducer and activator of transcription 1-alpha/beta

Cat.:

P1740Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Signal transducer and activator of transcription 1-alpha/beta

Cat.:

P1740Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human Signal transducer and activator of transcription 1-alpha/beta

Monoclonal Antibody for Human Signal transducer and activator of transcription 1-alpha/beta

Protein for Human Signal transducer and activator of transcription 1-alpha/beta

R&D Technical Data

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Precision

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Recovery

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References

1.

"Proteins of transcription factor ISGF-3: one gene encodes the 91- and 84-kDa ISGF-3 proteins that are activated by interferon alpha."
Schindler C. , Fu X.-Y. , Improta T. , Aebersold R. , Darnell J.E. Jr.
Proc. Natl. Acad. Sci. U.S.A.89:7836-7839(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ALPHA);PROTEIN SEQUENCE OF 514-524; 654-660 AND 667-672
2.

"Novel STAT1 alleles in a patient with impaired resistance to mycobacteria."
Kristensen I. , Veirum J.E. , Moeller B.K. , Christiansen M.
Submitted (2009-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ALPHA)
3.

NIEHS SNPs program
Submitted (2004-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM ALPHA)
tissue: Placenta.
tissue: Testis.
5.

"The full-ORF clone resource of the German cDNA consortium."
Bechtel S. , Rosenfelder H. , Duda A. , Schmidt C.P. , Ernst U. , Wellenreuther R. , Mehrle A. , Schuster C. , Bahr A. , Bloecker H. , Heubner D. , Hoerlein A. , Michel G. , Wedler H. , Koehrer K. , Ottenwaelder B. , Poustka A. , Wiemann S. , more...
BMC Genomics8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM ALPHA)
6.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM BETA)
7.

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM BETA)
tissue: Brain.
10.

"The genomic structure of the STAT genes: multiple exons in coincident sites in Stat1 and Stat2."
Yan R. , Qureshi S. , Zhong Z. , Wen Z. , Darnell J.E. Jr.
Nucleic Acids Res.23:459-463(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [GENOMIC DNA]
11.

"A transcription factor with SH2 and SH3 domains is directly activated by an interferon alpha-induced cytoplasmic protein tyrosine kinase(s)."
Fu X.Y.
Cell70:323-335(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION IN RESPONSE TO IFN-ALPHA
12.

"Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation."
Wen Z. , Zhong Z. , Darnell J.E. Jr.
Cell82:241-250(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-727;MUTAGENESIS
13.

"Phosphorylation and activation of the DNA binding activity of purified Stat1 by the Janus protein-tyrosine kinases and the epidermal growth factor receptor."
Quelle F.W. , Thierfelder W. , Witthuhn B.A. , Tang B. , Cohen S. , Ihle J.N.
J. Biol. Chem.270:20775-20780(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-701
14.

"The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals."
Gupta S. , Yan H. , Wong L.H. , Ralph S. , Krolewski J. , Schindler C.
EMBO J.15:1075-1084(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TYROSINE PHOSPHORYLATION;HETERODIMERIZATION;DNA-BINDING;MUTAGENESIS
15.

"Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling."
Li X. , Leung S. , Kerr I.M. , Stark G.R.
Mol. Cell. Biol.17:2048-2056(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH IFNAR1 AND IFNAR2;PHOSPHORYLATION
16.

"Inhibition of Stat1-mediated gene activation by PIAS1."
Liu B. , Liao J. , Rao X. , Kushner S.A. , Chung C.D. , Chang D.D. , Shuai K.
Proc. Natl. Acad. Sci. U.S.A.95:10626-10631(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PIAS1;FUNCTION
tissue: B-cell.
17.

"Viral inhibition of interferon signal transduction."
Cebulla C.M. , Miller D.M. , Sedmak D.D.
Intervirology42:325-330(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
18.

"Sendai virus C protein physically associates with Stat1."
Takeuchi K. , Komatsu T. , Yokoo J. , Kato A. , Shioda T. , Nagai Y. , Gotoh B.
Genes Cells6:545-557(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SENDAI VIRUS C PROTEIN
19.

"Focal adhesion kinase activates Stat1 in integrin-mediated cell migration and adhesion."
Xie B. , Zhao J. , Kitagawa M. , Durbin J. , Madri J.A. , Guan J.L. , Fu X.Y.
J. Biol. Chem.276:19512-19523(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PTK2/FAK1;PHOSPHORYLATION
20.

"Identification of a nuclear Stat1 protein tyrosine phosphatase."
ten Hoeve J. , de Jesus Ibarra-Sanchez M. , Fu Y. , Zhu W. , Tremblay M. , David M. , Shuai K.
Mol. Cell. Biol.22:5662-5668(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION;DEPHOSPHORYLATION BY PTPN2
21.

"PIAS proteins promote SUMO-1 conjugation to STAT1."
Ungureanu D. , Vanhatupa S. , Kotaja N. , Yang J. , Aittomaeki S. , Jaenne O.A. , Palvimo J.J. , Silvennoinen O.
Blood102:3311-3313(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUMOYLATION AT LYS-703;FUNCTION;MUTAGENESIS OF LYS-703
22.

"SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation."
Rogers R.S. , Horvath C.M. , Matunis M.J.
J. Biol. Chem.278:30091-30097(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUMOYLATION AT LYS-703;FUNCTION;MUTAGENESIS OF LYS-110 AND LYS-703
23.

"Signal transduction via the stem cell factor receptor/c-Kit."
Ronnstrand L.
Cell. Mol. Life Sci.61:2535-2548(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON ROLE IN KIT SIGNALING
24.

"Protein kinase Cdelta regulates apoptosis via activation of STAT1."
DeVries T.A. , Kalkofen R.L. , Matassa A.A. , Reyland M.E.
J. Biol. Chem.279:45603-45612(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-727;FUNCTION;SUBCELLULAR LOCATION;MUTAGENESIS OF SER-727
25.

"Proteomic identification of proteins conjugated to ISG15 in mouse and human cells."
Giannakopoulos N.V. , Luo J.K. , Papov V. , Zou W. , Lenschow D.J. , Jacobs B.S. , Borden E.C. , Li J. , Virgin H.W. , Zhang D.E.
Biochem. Biophys. Res. Commun.336:496-506(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ISGYLATION
26.

"Hepatitis C virus expression suppresses interferon signaling by degrading STAT1."
Lin W. , Choe W.H. , Hiasa Y. , Kamegaya Y. , Blackard J.T. , Schmidt E.V. , Chung R.T.
Gastroenterology128:1034-1041(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HEPATITIS C VIRUS CORE PROTEIN
27.

"Sustained phosphorylation of mutated FGFR3 is a crucial feature of genetic dwarfism and induces apoptosis in the ATDC5 chondrogenic cell line via PLCgamma-activated STAT1."
Harada D. , Yamanaka Y. , Ueda K. , Nishimura R. , Morishima T. , Seino Y. , Tanaka H.
Bone41:273-281(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION IN RESPONSE TO ACTIVATED FGFR3;PHOSPHORYLATION AT TYR-701
28.

"Fibroblast growth factor receptor-induced phosphorylation of STAT1 at the Golgi apparatus without translocation to the nucleus."
Citores L. , Bai L. , Sorensen V. , Olsnes S.
J. Cell. Physiol.212:148-156(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION IN RESPONSE TO ACTIVATED FGFR1; FGFR2; FGFR3 AND FGFR4
29.

"MAPK-induced Ser727 phosphorylation promotes SUMOylation of STAT1."
Vanhatupa S. , Ungureanu D. , Paakkunainen M. , Silvennoinen O.
Biochem. J.409:179-185(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-727;INTERACTION WITH PIAS1;SUMOYLATION;MUTAGENESIS OF TYR-701 AND SER-727
30.

"System-wide investigation of ErbB4 reveals 19 sites of Tyr phosphorylation that are unusually selective in their recruitment properties."
Kaushansky A. , Gordus A. , Budnik B.A. , Lane W.S. , Rush J. , MacBeath G.
Chem. Biol.15:808-817(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ERBB4
31.

"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-727;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
32.

"Analysis of STAT1 activation by six FGFR3 mutants associated with skeletal dysplasia undermines dominant role of STAT1 in FGFR3 signaling in cartilage."
Krejci P. , Salazar L. , Kashiwada T.A. , Chlebova K. , Salasova A. , Thompson L.M. , Bryja V. , Kozubik A. , Wilcox W.R.
PLoS ONE3:E3961-E3961(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PHOSPHORYLATION AT TYR-701 IN RESPONSE TO CONSTITUTIVELY ACTIVATED FGFR3
33.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-727;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
34.

"PRMT1-mediated arginine methylation of PIAS1 regulates STAT1 signaling."
Weber S. , Maass F. , Schuemann M. , Krause E. , Suske G. , Bauer U.M.
Genes Dev.23:118-132(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PIAS1
35.

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-727;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Leukemic T-cell.
36.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-727;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
37.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
38.

"Mechanisms of STAT protein activation by oncogenic KIT mutants in neoplastic mast cells."
Chaix A. , Lopez S. , Voisset E. , Gros L. , Dubreuil P. , De Sepulveda P.
J. Biol. Chem.286:5956-5966(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-701 IN RESPONSE TO KIT SIGNALING;PHOSPHORYLATION AT SER-727
39.

"Inhibitor of kappaB kinase epsilon (IKK(epsilon)), STAT1, and IFIT2 proteins define novel innate immune effector pathway against West Nile virus infection."
Perwitasari O. , Cho H. , Diamond M.S. , Gale M. Jr.
J. Biol. Chem.286:44412-44423(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-701; SER-708 AND SER-727;MUTAGENESIS OF TYR-701; SER-708 AND SER-727
40.

"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
41.

"Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA."
Chen X. , Vinkemeier U. , Zhao Y. , Jeruzalmi D. , Darnell J.E. Jr. , Kuriyan J.
Cell93:827-839(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF 136-710;COILED-COIL
42.

"Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation."
Dupuis S. , Dargemont C. , Fieschi C. , Thomassin N. , Rosenzweig S. , Harris J. , Holland S.M. , Schreiber R.D. , Casanova J.-L.
Science293:300-303(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT IMD31A SER-706
43.

"Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency."
Dupuis S. , Jouanguy E. , Al-Hajjar S. , Fieschi C. , Al-Mohsen I.Z. , Al-Jumaah S. , Yang K. , Chapgier A. , Eidenschenk C. , Eid P. , Al-Ghonaium A. , Tufenkeji H. , Frayha H. , Al-Gazlan S. , Al-Rayes H. , Schreiber R.D. , Gresser I. , Casanova J.L.
Nat. Genet.33:388-391(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT IMD31B PRO-600
44.

"Nipah virus V and W proteins have a common STAT1-binding domain yet inhibit STAT1 activation from the cytoplasmic and nuclear compartments, respectively."
Shaw M.L. , Garcia-Sastre A. , Palese P. , Basler C.F.
J. Virol.78:5633-5641(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NIPAH V AND W PROTEINS
45.

"Novel STAT1 alleles in otherwise healthy patients with mycobacterial disease."
Chapgier A. , Boisson-Dupuis S. , Jouanguy E. , Vogt G. , Feinberg J. , Prochnicka-Chalufour A. , Casrouge A. , Yang K. , Soudais C. , Fieschi C. , Santos O.F. , Bustamante J. , Picard C. , de Beaucoudrey L. , Emile J.F. , Arkwright P.D. , Schreiber R.D. , Rolinck-Werninghaus C. , more...
PLoS Genet.2:E131-E131(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS IMD31A GLN-320 AND HIS-463;CHARACTERIZATION OF VARIANTS GLN-320; HIS-463 AND SER-706
46.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] ALA-491
47.

"A novel form of human STAT1 deficiency impairing early but not late responses to interferons."
Kong X.F. , Ciancanelli M. , Al-Hajjar S. , Alsina L. , Zumwalt T. , Bustamante J. , Feinberg J. , Audry M. , Prando C. , Bryant V. , Kreins A. , Bogunovic D. , Halwani R. , Zhang X.X. , Abel L. , Chaussabel D. , Al-Muhsen S. , Casanova J.L. , more...
Blood116:5895-5906(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT IMD31B ASN-201;CHARACTERIZATION OF VARIANT IMD31B ASN-201
48.

"Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis."
Liu L. , Okada S. , Kong X.F. , Kreins A.Y. , Cypowyj S. , Abhyankar A. , Toubiana J. , Itan Y. , Audry M. , Nitschke P. , Masson C. , Toth B. , Flatot J. , Migaud M. , Chrabieh M. , Kochetkov T. , Bolze A. , Borghesi A. , more...
J. Exp. Med.208:1635-1648(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CANDF7 GLY-165; HIS-165; ASN-170; ARG-174; ILE-202; VAL-202; VAL-267; PRO-271; GLN-274; TRP-274; ILE-286 AND ALA-288;CHARACTERIZATION OF VARIANTS CANDF7 GLY-165 AND GLN-274
49.

"STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis."
van de Veerdonk F.L. , Plantinga T.S. , Hoischen A. , Smeekens S.P. , Joosten L.A. , Gilissen C. , Arts P. , Rosentul D.C. , Carmichael A.J. , Smits-van der Graaf C.A. , Kullberg B.J. , van der Meer J.W. , Lilic D. , Veltman J.A. , Netea M.G.
N. Engl. J. Med.365:54-61(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CANDF7 VAL-267 AND TRP-274
50.

"Dominant-negative STAT1 SH2 domain mutations in unrelated patients with Mendelian susceptibility to mycobacterial disease."
Tsumura M. , Okada S. , Sakai H. , Yasunaga S. , Ohtsubo M. , Murata T. , Obata H. , Yasumi T. , Kong X.F. , Abhyankar A. , Heike T. , Nakahata T. , Nishikomori R. , Al-Muhsen S. , Boisson-Dupuis S. , Casanova J.L. , Alzahrani M. , Shehri M.A. , more...
Hum. Mutat.33:1377-1387(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS IMD31A GLU-637 AND ARG-673;CHARACTERIZATION OF VARIANTS IMD31A GLU-637 AND ARG-673

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