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Index > Protein center > Stk16(Gene name) > Mouse
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  • Stk16 (Gene name),
  • Serine/threonine-protein kinase 16 (Protein name ),  STK16_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Stk16(Edpk;Krct;Mpsk1;Pkl12;Tsf1);
    Protein name:
    Serine/threonine-protein kinase 16;
    Alternative:
    Myristoylated and palmitoylated serine/threonine-protein kinase(MPSK);Embryo-derived protein kinase(Edpk);Protein kinase PKL12;Protein kinase Krct;2.7.10.2;Tyrosine-protein kinase STK16);TGF-beta-stimulated factor 1(TSF-1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Monomer (By similarity). Interacts with DRG1 (via its N-terminal); the interaction phosphorylates DRG1.
    Function:
    Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates (By similarity). May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.
    Subcellular Location:
    Cytoplasm perinuclear region Membrane Lipid-anchor Associates with Golgi and Golgi-derived vesicles.
    Protein Attributes:
    Sequence length:
    305
    Sequence:
    50:
    MGHALCVCSR | GTVIIDNKRY | LFVQKLGEGG | FSYVDLVEGL | HDGHFYALKR | 
    100:
    ILCHEQQDQE | EAQREAEMHR | LFQHPNILRL | MAYSLKERGA | KHEAWLLLPF | 
    150:
    FKKGTLWNEI | ERLKDQGSFL | TEDQILPLLL | GISRGLEAIH | AKGYAHRDLK | 
    200:
    PTNILLGDEG | QPVLMDLGSM | NQACIQVEGS | RQALALQDWA | AQRCTISYRA | 
    250:
    PELFSVQSHC | VIDERTDVWS | LGCVLYAMMF | GEGPYDMVFQ | KGDSVALAVQ | 
    300:
    NELSIPQSPR | HSSALRQLLS | SMMTVDPQQR | PHIPVLLSQL | EALQPPAPGQ | 
    305:
    HTTQI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    KEGG:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Serine/threonine-protein kinase 16
    ELISA Kit for Mouse Serine/threonine-protein kinase 16
    ELISA Kit for Mouse Serine/threonine-protein kinase 16
    CLIA Kit for Mouse Serine/threonine-protein kinase 16
    CLIA Kit for Mouse Serine/threonine-protein kinase 16
    CLIA Kit for Mouse Serine/threonine-protein kinase 16
    Polyclonal Antibody for Mouse Serine/threonine-protein kinase 16
    Polyclonal Antibody for Mouse Serine/threonine-protein kinase 16
    Polyclonal Antibody for Mouse Serine/threonine-protein kinase 16
    Monoclonal Antibody for Mouse Serine/threonine-protein kinase 16
    Monoclonal Antibody for Mouse Serine/threonine-protein kinase 16
    Monoclonal Antibody for Mouse Serine/threonine-protein kinase 16
    Protein for Mouse Serine/threonine-protein kinase 16
    Protein for Mouse Serine/threonine-protein kinase 16
    Protein for Mouse Serine/threonine-protein kinase 16

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    Precision
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    Linearity
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    References
    1. 1.
      "Cloning, expression analysis, and functional characterization of PKL12, a member of a new subfamily of ser/thr kinases."
      Ligos J.M. , Gerwin N. , Fernandez P. , Gutierrez-Ramos J.-C. , Bernad A.
      Biochem. Biophys. Res. Commun.249:380-384(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;AUTOPHOSPHORYLATION;DEVELOPMENTAL STAGE;TISSUE SPECIFICITY
    2. 2.
      "Molecular cloning and characterization of a novel protein serine/threonine kinase highly expressed in mouse embryo."
      Kurioka K. , Nakagawa K. , Denda K. , Miyazawa K. , Kitamura N.
      Biochim. Biophys. Acta1443:275-284(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;FUNCTION
      tissue: Liver.
    3. 3.
      "Cloning and characterization of Krct, a member of a novel subfamily of serine/threonine kinases."
      Stairs D.B. , Perry Gardner H. , Ha S.I. , Copeland N.G. , Gilbert D.J. , Jenkins N.A. , Chodosh L.A.
      Hum. Mol. Genet.7:2157-2166(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: FVB.
      tissue: Mammary gland.
    4. 4.
      "Identification and characterization of a myristylated and palmitylated serine/threonine protein kinase."
      Berson A.E. , Young C. , Morrison S.L. , Fujii G.H. , Sheung J. , Wu B. , Bolen J.B. , Burkhardt A.L.
      Biochem. Biophys. Res. Commun.259:533-538(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    5. 5.
      "A novel transcriptional factor with Ser/Thr kinase activity involved in the transforming growth factor (TGF)-beta signalling pathway."
      Ohta S. , Takeuchi M. , Deguchi M. , Tsuji T. , Gahara Y. , Nagata K.
      Biochem. J.350:395-404(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
      strain: 129/SvJ.
    6. 6.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Liver.
    7. 7.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Mammary gland.
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