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Index > Protein center > SUCLG1(Gene name) > Human
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  • SUCLG1 (Gene name),
  • Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (Protein name ),  SUCA_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SUCLG1;
    Protein name:
    Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial;
    Alternative:
    Succinyl-CoA synthetase subunit alpha(SCS-alpha);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterodimer of an alpha and a beta subunit.
    Function:
    Catalyzes the ATP- or GTP-dependent ligation of succinate and CoA to form succinyl-CoA. The nature of the beta subunit determines the nucleotide specificity.
    Subcellular Location:
    Mitochondrion
    Protein Attributes:
    Sequence length:
    346
    Sequence:
    50:
    MTATLAAAAD | IATMVSGSSG | LAAARLLSRS | FLLPQNGIRH | CSYTASRQHL | 
    100:
    YVDKNTKIIC | QGFTGKQGTF | HSQQALEYGT | KLVGGTTPGK | GGQTHLGLPV | 
    150:
    FNTVKEAKEQ | TGATASVIYV | PPPFAAAAIN | EAIEAEIPLV | VCITEGIPQQ | 
    200:
    DMVRVKHKLL | RQEKTRLIGP | NCPGVINPGE | CKIGIMPGHI | HKKGRIGIVS | 
    250:
    RSGTLTYEAV | HQTTQVGLGQ | SLCVGIGGDP | FNGTDFIDCL | EIFLNDSATE | 
    300:
    GIILIGEIGG | NAEENAAEFL | KQHNSGPNSK | PVVSFIAGLT | APPGRRMGHA | 
    346:
    GAIIAGGKGG | AKEKISALQS | AGVVVSMSPA | QLGTTIYKEF | EKRKML
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    String:
    SMR:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Cat.:
    E3409r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Cat.:
    E3409h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Cat.:
    E3409b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Cat.:
    E3409m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Cat.:
    E3409p
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Cat.:
    U3409b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Cat.:
    U3409p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Cat.:
    U3409r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Cat.:
    U3409h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Cat.:
    U3409m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Cat.:
    P3409Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Cat.:
    P3409Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Polyclonal Antibody for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Polyclonal Antibody for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Cat.:
    P3409Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Monoclonal Antibody for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Monoclonal Antibody for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Monoclonal Antibody for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Monoclonal Antibody for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Protein for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Protein for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Protein for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Protein for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
    Protein for Human Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 3-346
      tissue: Lung.
    3. 3.
      "Sequence of the alpha subunit of succinyl-CoA synthetase in human."
      Tews K.N. , Mehus J.G. , Johnson J.D. , Milavetz B.I. , Lambeth D.O.
      Submitted (2000-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 4-346
    4. 4.
      "The molecular basis for cross-reaction anti-dystrophin antibody with alpha-actinin."
      James M. , Man N.T. , Edwards Y.H. , Morris G.E.
      Biochim. Biophys. Acta1360:169-176(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 12-145
      tissue: Brain.
      tissue: Skeletal muscle.
    5. 5.
      "Deficiency of the alpha subunit of succinate-coenzyme A ligase causes fatal infantile lactic acidosis with mitochondrial DNA depletion."
      Ostergaard E. , Christensen E. , Kristensen E. , Mogensen B. , Duno M. , Shoubridge E.A. , Wibrand F.
      Am. J. Hum. Genet.81:383-387(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN MTDPS9
    6. 6.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-54;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    8. 8.
      "A novel missense mutation in SUCLG1 associated with mitochondrial DNA depletion, encephalomyopathic form, with methylmalonic aciduria."
      Ostergaard E. , Schwartz M. , Batbayli M. , Christensen E. , Hjalmarson O. , Kollberg G. , Holme E.
      Eur. J. Pediatr.169:201-205(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MTDPS9 ALA-85
    9. 9.
      "The severity of phenotype linked to SUCLG1 mutations could be correlated with residual amount of SUCLG1 protein."
      Rouzier C. , Le Guedard-Mereuze S. , Fragaki K. , Serre V. , Miro J. , Tuffery-Giraud S. , Chaussenot A. , Bannwarth S. , Caruba C. , Ostergaard E. , Pellissier J.F. , Richelme C. , Espil C. , Chabrol B. , Paquis-Flucklinger V.
      J. Med. Genet.47:670-676(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MTDPS9 ARG-170
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MTDPS9 LEU-14
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