Supv3l1 ELISA Kit for Mouse(Mus musculus) | EIAab.comSupv3l1 ELISA Kit for Mouse(Mus musculus)

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Supv3l1 (Gene name),

ATP-dependent RNA helicase SUPV3L1, mitochondrial (Protein name ), SUV3_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Supv3l1(Suv3l1);

Protein name:

ATP-dependent RNA helicase SUPV3L1, mitochondrial;

Alternative:

Suppressor of var1 3-like protein 1(SUV3-like protein 1);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer; in free form. Component of the mitochondrial degradosome (mtEXO) complex which is a heteropentamer containing 2 copies of SUPV3L1 and 3 copies of PNPT1. Interacts with HBXIP, WRN and BLM.

Function:

Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.

Subcellular Location:

Nucleus Mitochondrion matrix Mitochondrion matrix mitochondrion nucleoid

Protein Attributes:

Sequence length:

779

Sequence:

50:

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450:

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750:

779:

LQKEWLTQQP | EHSREKVGTR | RKKKDPDSD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.235898

String:

Q80YD1

KEGG:

mmu:338359

SMR:

Q80YD1

Pfam:

PF00271

Uniprot:

Q80YD1

FOR

ELISA Kit for Mouse ATP-dependent RNA helicase SUPV3L1, mitochondrial

CLIA Kit for Mouse ATP-dependent RNA helicase SUPV3L1, mitochondrial

Polyclonal Antibody for Mouse ATP-dependent RNA helicase SUPV3L1, mitochondrial

Monoclonal Antibody for Mouse ATP-dependent RNA helicase SUPV3L1, mitochondrial

Protein for Mouse ATP-dependent RNA helicase SUPV3L1, mitochondrial

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A null mutation existed in SUV3L1 of SAMP8/Ta."
Zhang C. , Yang T. , Liu G. , Chen Q.
Submitted (2005-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Embryo.
3.

"Interaction of human SUV3 RNA/DNA helicase with BLM helicase; loss of the SUV3 gene results in mouse embryonic lethality."
Pereira M. , Mason P. , Szczesny R.J. , Maddukuri L. , Dziwura S. , Jedrzejczak R. , Paul E. , Wojcik A. , Dybczynska L. , Tudek B. , Bartnik E. , Klysik J. , Bohr V.A. , Stepien P.P.
Mech. Ageing Dev.128:609-617(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE

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