SWAP70 ELISA Kit for Bovine(Bos taurus) | EIAab.comSWAP70 ELISA Kit for Bovine(Bos taurus)

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Index > Protein center > SWAP70(Gene name) > Bovine

SWAP70 (Gene name),

Switch-associated protein 70 (Protein name ), SWP70_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

SWAP70;

Protein name:

Switch-associated protein 70(SWAP-70);

Alternative:

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

The SWAP complex consists of NPM1, NCL, PARP1 and SWAP70.

Function:

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.

Subcellular Location:

Cytoplasm Cell membrane Nucleus Cell projection lamellipodium In resting B-cells it is localized mainly in the cytoplasm and upon cell activation it is recruited to the plasma membrane and then translocates to the nucleus. In activated, class-switching B-cells it is associated with membrane IgG but not IgM. Localized to loose actin filament arrays located behind actively extending lamellipodia.

Protein Attributes:

Sequence length:

585

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

585:

GSKNAHLITN | WGPAAFTQAE | LEERQKSWKE | KKTTE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00169

STRING:

9913.ENSBTAP00000002578

SMR:

P0C1G6

UniGene:

Bt.15774

Uniprot:

P0C1G6

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ELISA Kit for Bovine SWAP-70

Cat.:

E3416h

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96T

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ELISA Kit for Bovine SWAP-70

Cat.:

E3416c

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96T

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ELISA Kit for Bovine SWAP-70

Cat.:

E3416m

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Packing:

96T

ELISA Kit for Bovine SWAP-70

Cat.:

E3416b

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Packing:

96T

CLIA Kit for Bovine SWAP-70

Cat.:

U3416h

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MSDS:

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Packing:

96T

CLIA Kit for Bovine SWAP-70

Cat.:

U3416b

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Packing:

96T

CLIA Kit for Bovine SWAP-70

MSDS:

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CLIA Kit for Bovine SWAP-70

Cat.:

U3416m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Bovine SWAP-70

Cat.:

P3416Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine SWAP-70

Cat.:

P3416Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine SWAP-70

Monoclonal Antibody for Bovine SWAP-70

Protein for Bovine SWAP-70

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Bovine genome sequencing program: full-length cDNA sequencing."
Moore S. , Alexander L. , Brownstein M. , Guan L. , Lobo S. , Meng Y. , Tanaguchi M. , Wang Z. , Yu J. , Prange C. , Schreiber K. , Shenmen C. , Wagner L. , Bala M. , Barbazuk S. , Barber S. , Babakaiff R. , Beland J. , more...
Submitted (2005-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
2.

"SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling."
Shinohara M. , Terada Y. , Iwamatsu A. , Shinohara A. , Mochizuki N. , Higuchi M. , Gotoh Y. , Ihara S. , Nagata S. , Itoh H. , Fukui Y. , Jessberger R.
Nature416:759-763(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 33-40; 448-457; 466-474; 482-490 AND 492-507;MUTAGENESIS OF ARG-230 AND LYS-291;DOMAIN;FUNCTION;SUBCELLULAR LOCATION
tissue: Brain.

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