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Index > Protein center > Sycp2(Gene name) > Mouse
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  • Sycp2 (Gene name),
  • Synaptonemal complex protein 2 (Protein name ),  SYCP2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Sycp2(Scp2);
    Protein name:
    Synaptonemal complex protein 2(SCP-2);
    Alternative:
    Synaptonemal complex lateral element protein;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Heterodimer with SYCP3. Interacts with SYCP3, SMC1A and SMC3.
    Function:
    Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements.
    Subcellular Location:
    Nucleus In axial/lateral elements of the tripartite segments of synaptonemal complexes.
    Protein Attributes:
    Sequence length:
    1500
    Sequence:
    50:
    MPVRPDLQQL | EKCIDDALRK | NDFKPLLALL | QIDICEDVKI | KCSKQFLRKL | 
    100:
    DDLICRELNK | KDIQTVSSIL | ISIGRCSKNI | FILGQAGLQT | MIKQGLVQKM | 
    150:
    VSWFENSKEI | ILNQQQSKDE | AVMNMIEDLF | DLLMVIYDIS | DEGKNQVLES | 
    200:
    FIPQICALVI | DSRVNFCIQQ | EALKKMNLML | DRIPQDANKI | LSNQEMLTLM | 
    250:
    SNMGERILDV | GDYELQVGIV | EALCRMTTEK | RRQELAYEWF | SMDFIANAFK | 
    300:
    EIKDCEFETD | CRIFLNLVNG | ILGDKRRVYT | FPCLSAFLGK | YELQIPSDEK | 
    350:
    LEEFWIDFNL | GSHTLSFYIA | GDEEDHQWEA | VTVPEEKVQM | YNIEVRESKK | 
    400:
    LLTLTLKNIV | KISKKEGKEL | LFYFDESLEI | TNVTKKVFGG | NKYKEFTRKQ | 
    450:
    GISVAKTSIH | VLFDASGSQI | LVPESQPSPV | KENLIHLKEK | SDIQKKLVNP | 
    500:
    LELGNSSSQD | EITTPSRKKM | SEASMIVPDT | DRYTVRSPIL | LINTSTPRRS | 
    550:
    REPLQAINSV | EKAVSKTSES | GMDYAASPKS | RQSDGRKRWN | NRANHNKTTA | 
    600:
    VIQNKQYEDN | ESPDQNFNEI | EDTLSNVSSA | VGKVDKPVLP | GVLDISKNTT | 
    650:
    HSRWACWTPV | TTIKLCNNQR | SRALPGDTCT | QDTGVNKKCT | KQKSVSDDDS | 
    700:
    EETQKGKYSK | DVIKCNKSDE | AEFCERNIQE | QNHPKYSQKK | NTANAKKSDW | 
    750:
    HIESETTYKS | VLLNKTTEES | LIYKKTCVLS | KDVNTTICDK | SPSRKSKRNH | 
    800:
    TKSRKELMSE | LTSCELEEIP | VRENSKGKRF | TGASESLINQ | ISRRYNPSDS | 
    850:
    MMSTRKLKEP | QDGSGFSKKP | DLQFNKVQRK | SYRKLKATVV | NVTSECPLDD | 
    900:
    VYNFSLNGAD | EPVIKLGIQE | FQATTREASM | DNSLKLVKNH | DEHDPFLKTK | 
    950:
    DKRMLSYEKK | TLLSDTETEC | GCDDSKTDIS | WLKEPKTKRL | MDYSRNKNTT | 
    1000:
    KYKSRKSRSS | MEKGQPRPTM | VLNKNSMKND | YEVVVDGRTR | LPRRATKTKK | 
    1050:
    NYKDLSTSES | ESESEKECSY | LFKDKLPTKE | ETIHSRAQTK | KLPEKQQKVF | 
    1100:
    NSEALKGQPS | EEQKNSSRLR | EGREDSLCLS | SASVSRSSSS | VEVMRCTEKI | 
    1150:
    TERDFTQDYD | YITKSLSPYP | KAPSPEFLNG | NNSVVGRGQS | PRISETSAMC | 
    1200:
    VRKSYSPASG | PPFSPRHTPT | KNNSVVNMKK | ANSVINNQRT | QHCNSYSDVS | 
    1250:
    SNSSEKLYME | PESPESCDNH | MQNKREGNHA | ASPLSLSSEK | IEKMWFDMPS | 
    1300:
    ENTHVSGPSQ | RGSKRRMYLE | DDELSNSNEA | EVEEAEEREH | LLSKKRCQWE | 
    1350:
    NSDQHTFKTS | LSTPDFSVPK | DWQQELQGAG | MFYDNISSDY | KRKTDSQHKI | 
    1400:
    MDDFTTKTLK | LTQQHLMAMT | SQAQGRRDEN | VEKFQVTLLD | ELEKVEKDSQ | 
    1450:
    TLRDLEKELV | DIEEKLVQKM | RAYHRCERER | FRVLKTSLDK | SFLVYNSVYE | 
    1500:
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse SCP-2
    ELISA Kit for Mouse SCP-2
    ELISA Kit for Mouse SCP-2
    CLIA Kit for Mouse SCP-2
    CLIA Kit for Mouse SCP-2
    CLIA Kit for Mouse SCP-2
    Polyclonal Antibody for Mouse SCP-2
    Polyclonal Antibody for Mouse SCP-2
    Polyclonal Antibody for Mouse SCP-2
    Monoclonal Antibody for Mouse SCP-2
    Monoclonal Antibody for Mouse SCP-2
    Monoclonal Antibody for Mouse SCP-2
    Protein for Mouse SCP-2
    Protein for Mouse SCP-2
    Protein for Mouse SCP-2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Mouse SYCP2 is required for synaptonemal complex assembly and chromosomal synapsis during male meiosis."
      Yang F. , De La Fuente R. , Leu N.A. , Baumann C. , McLaughlin K.J. , Wang P.J.
      J. Cell Biol.173:497-507(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBUNIT
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-544
      strain: C57BL/6J.
      tissue: Placenta.
    4. 4.
      "A meiotic chromosomal core consisting of cohesin complex proteins recruits DNA recombination proteins and promotes synapsis in the absence of an axial element in mammalian meiotic cells."
      Pelttari J. , Hoja M.-R. , Yuan L. , Liu J.-G. , Brundell E. , Moens P. , Santucci-Darmanin S. , Jessberger R. , Barbero J.L. , Heyting C. , Hoeoeg C.
      Mol. Cell. Biol.21:5667-5677(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TEX11
    6. 6.
      "Phosphorylation of chromosome core components may serve as axis marks for the status of chromosomal events during mammalian meiosis."
      Fukuda T. , Pratto F. , Schimenti J.C. , Turner J.M. , Camerini-Otero R.D. , Hoeoeg C.
      PLoS Genet.8:E1002485-E1002485(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;PHOSPHORYLATION
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