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Index > Protein center > IARS(Gene name) > Human
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  • IARS (Gene name),
  • Isoleucyl-tRNA synthetase, cytoplasmic (Protein name ),  SYIC_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    IARS;
    Protein name:
    Isoleucyl-tRNA synthetase, cytoplasmic;
    Alternative:
    Isoleucine--tRNA ligase(IRS;IleRS);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Part of a multisubunit complex that groups tRNA ligases for Arg, Asp, Glu, Gln, Ile, Leu, Lys, Met and Pro.
    Function:
    N/A
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    1262
    Sequence:
    50:
    MLQQVPENIN | FPAEEEKILE | FWTEFNCFQE | CLKQSKHKPK | FTFYDGPPFA | 
    100:
    TGLPHYGHIL | AGTIKDIVTR | YAHQSGFHVD | RRFGWDCHGL | PVEYEIDKTL | 
    150:
    GIRGPEDVAK | MGITEYNNQC | RAIVMRYSAE | WKSTVSRLGR | WIDFDNDYKT | 
    200:
    LYPQFMESVW | WVFKQLYDKG | LVYRGVKVMP | FSTACNTPLS | NFESHQNYKD | 
    250:
    VQDPSVFVTF | PLEEDETVSL | VAWTTTPWTL | PSNLAVCVNP | EMQYVKIKDV | 
    300:
    ARGRLLILME | ARLSALYKLE | SDYEILERFP | GAYLKGKKYR | PLFDYFLKCK | 
    350:
    ENGAFTVLVD | NYVKEEEGTG | VVHQAPYFGA | EDYRVCMDFN | IIRKDSLPVC | 
    400:
    PVDASGCFTT | EVTDFAGQYV | KDADKSIIRT | LKEQGRLLVA | TTFTHSYPFC | 
    450:
    WRSDTPLIYK | AVPSWFVRVE | NMVDQLLRNN | DLCYWVPELV | REKRFGNWLK | 
    500:
    DARDWTISRN | RYWGTPIPLW | VSDDFEEVVC | IGSVAELEEL | SGAKISDLHR | 
    550:
    ESVDHLTIPS | RCGKGSLHRI | SEVFDCWFES | GSMPYAQVHY | PFENKREFED | 
    600:
    AFPADFIAEG | IDQTRGWFYT | LLVLATALFG | QPPFKNVIVN | GLVLASDGQK | 
    650:
    MSKRKKNYPD | PVSIIQKYGA | DALRLYLINS | PVVRAENLRF | KEEGVRDVLK | 
    700:
    DVLLPWYNAY | RFLIQNVLRL | QKEEEIEFLY | NENTVRESPN | ITDRWILSFM | 
    750:
    QSLIGFFETE | MAAYRLYTVV | PRLVKFVDIL | TNWYVRMNRR | RLKGENGMED | 
    800:
    CVMALETLFS | VLLSLCRLMA | PYTPFLTELM | YQNLKVLIDP | VSVQDKDTLS | 
    850:
    IHYLMLPRVR | EELIDKKTES | AVSQMQSVIE | LGRVIRDRKT | IPIKYPLKEI | 
    900:
    VVIHQDPEAL | KDIKSLEKYI | IEELNVRKVT | LSTDKNKYGI | RLRAEPDHMV | 
    950:
    LGKRLKGAFK | AVMTSIKQLS | SEELEQFQKT | GTIVVEGHEL | HDEDIRLMYT | 
    1000:
    FDQATGGTAQ | FEAHSDAQAL | VLLDVTPDQS | MVDEGMAREV | INRIQKLRKK | 
    1050:
    CNLVPTDEIT | VYYKAKSEGT | YLNSVIESHT | EFIFTTIKAP | LKPYPVSPSD | 
    1100:
    KVLIQEKTQL | KGSELEITLT | RGSSLPGPAC | AYVNLNICAN | GSEQGGVLLL | 
    1150:
    ENPKGDNRLD | LLKLKSVVTS | IFGVKNTELA | VFHDETEIQN | QTDLLSLSGK | 
    1200:
    TLCVTAGSAP | SLINSSSTLL | CQYINLQLLN | AKPQECLMGT | VGTLLLENPL | 
    1250:
    GQNGLTHQGL | LYEAAKVFGL | RSRKLKLFLN | ETQTQEITED | IPVKTLNMKT | 
    1262:
    VYVSVLPTTA | DF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    String:
    KEGG:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Isoleucyl-tRNA synthetase, cytoplasmic
    ELISA Kit for Human Isoleucyl-tRNA synthetase, cytoplasmic
    CLIA Kit for Human Isoleucyl-tRNA synthetase, cytoplasmic
    CLIA Kit for Human Isoleucyl-tRNA synthetase, cytoplasmic
    Polyclonal Antibody for Human Isoleucyl-tRNA synthetase, cytoplasmic
    Polyclonal Antibody for Human Isoleucyl-tRNA synthetase, cytoplasmic
    Monoclonal Antibody for Human Isoleucyl-tRNA synthetase, cytoplasmic
    Monoclonal Antibody for Human Isoleucyl-tRNA synthetase, cytoplasmic
    Protein for Human Isoleucyl-tRNA synthetase, cytoplasmic
    Protein for Human Isoleucyl-tRNA synthetase, cytoplasmic

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Human cytoplasmic isoleucyl-tRNA synthetase: selective divergence of the anticodon-binding domain and acquisition of a new structural unit."
      Shiba K. , Suzuki N. , Shigesada K. , Schimmel P. , Noda T.
      Proc. Natl. Acad. Sci. U.S.A.91:7435-7439(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Human isoleucyl-tRNA synthetase: sequence of the cDNA, alternative mRNA splicing, and the characteristics of an unusually long C-terminal extension."
      Nichols R.C. , Raben N. , Boerkoel C.F. , Plotz P.H.
      Gene155:299-304(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE;SUBCELLULAR LOCATION;VARIANT ILE-769
      tissue: Liver.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Trachea.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT GLU-1182
      tissue: Colon endothelium.
    5. 5.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1047;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    8. 8.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1047 AND SER-1049;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 11.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1047;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 12.
      "Mutations in the enzyme glutathione peroxidase 4 cause Sedaghatian-type spondylometaphyseal dysplasia."
      FORGE Canada Consortium , Smith A.C. , Mears A.J. , Bunker R. , Ahmed A. , MacKenzie M. , Schwartzentruber J.A. , Beaulieu C.L. , Ferretti E. , Majewski J. , Bulman D.E. , Celik F.C. , Boycott K.M. , Graham G.E.
      J. Med. Genet.51:470-474(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TYR-302 AND THR-1188
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