SYNRG ELISA Kit for Human(Homo sapiens) | EIAab.comSYNRG ELISA Kit for Human(Homo sapiens) | EIAab.com

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SYNRG (Gene name),

Synergin gamma (Protein name ), SYNRG_HUMAN from NCBI database.

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General Annotation

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Antigen Annotation

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3D

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Predicted Eptitope

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Vaild Sequence

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Related Databases

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Gene name:

SYNRG(AP1GBP1;SYNG);

Protein name:

Synergin gamma;

Alternative:

Gamma-synergin;AP1 subunit gamma-binding protein 1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with SCAMP1 via its EH-domain (By similarity). Interacts with GGA1, GGA2 and GGA3. Interacts with the AP1G1 and AP1G2 subunits of the adapter protein complexes AP-1.

Function:

May play a role in endocytosis and/or membrane trafficking at the trans-Golgi network (TGN). May act by linking the adapter protein complex AP-1 to other proteins.

Subcellular Location:

Cytoplasm Golgi apparatus trans-Golgi network membrane Peripheral membrane protein Associates with membranes via the adapter protein complex AP-1. Colocalizes with AP1G1.

Protein Attributes:

Sequence length:

1314

Sequence:

50:

MALRPGAGSG | GGGAAGAGAG | SAGGGGFMFP | VAGGIRPPQA | GLMPMQQQGF |

100:

PMVSVMQPNM | QGIMGMNYSS | QMSQGPIAMQ | AGIPMGPMPA | AGMPYLGQAP |

150:

FLGMRPPGPQ | YTPDMQKQFA | EEQQKRFEQQ | QKLLEEERKR | RQFEEQKQKL |

200:

RLLSSVKPKT | GEKSRDDALE | AIKGNLDGFS | RDAKMHPTPA | SHPKKPGPSL |

250:

EEKFLVSCDI | STSGQEQIKL | NTSEVGHKAL | GPGSSKKYPS | LMASNGVAVD |

300:

GCVSGTTTAE | AENTSDQNLS | IEESGVGVFP | SQDPAQPRMP | PWIYNESLVP |

350:

DAYKKILETT | MTPTGIDTAK | LYPILMSSGL | PRETLGQIWA | LANRTTPGKL |

400:

TKEELYTVLA | MIAVTQRGVP | AMSPDALNQF | PAAPIPTLSG | FSMTLPTPVS |

450:

QPTVIPSGPA | GSMPLSLGQP | VMGINLVGPV | GGAAAQASSG | FIPTYPANQV |

500:

VKPEEDDFQD | FQDASKSGSL | DDSFSDFQEL | PASSKTSNSQ | HGNSAPSLLM |

550:

PLPGTKALPS | MDKYAVFKGI | AADKSSENTV | PPGDPGDKYS | AFRELEQTAE |

600:

NKPLGESFAE | FRSAGTDDGF | TDFKTADSVS | PLEPPTKDKT | FPPSFPSGTI |

650:

QQKQQTQVKN | PLNLADLDMF | SSVNCSSEKP | LSFSAVFSTS | KSVSTPQSTG |

700:

SAATMTALAA | TKTSSLADDF | GEFSLFGEYS | GLAPVGEQDD | FADFMAFSNS |

750:

SISSEQKPDD | KYDALKEEAS | PVPLTSNVGS | TVKGGQNSTA | ASTKYDVFRQ |

800:

LSLEGSGLGV | EDLKDNTPSG | KSDDDFADFH | SSKFSSINSD | KSLGEKAVAF |

850:

RHTKEDSASV | KSLDLPSIGG | SSVGKEDSED | ALSVQFDMKL | ADVGGDLKHV |

900:

MSDSSLDLPT | VSGQHPPAAD | IEDLKYAAFG | SYSSNFAVST | LTSYDWSDRD |

950:

DATQGRKLSP | FVLSAGSGSP | SATSILQKKE | TSFGSSENIT | MTSLSKVTTF |

1000:

VSEDALPETT | FPALASFKDT | IPQTSEQKEY | ENRDYKDFTK | QDLPTAERSQ |

1050:

EATCPSPASS | GASQETPNEC | SDDFGEFQSE | KPKISKFDFL | VATSQSKMKS |

1100:

SEEMIKSELA | TFDLSVQGSH | KRSLSLGDKE | ISRSSPSPAL | EQPFRDRSNT |

1150:

LNEKPALPVI | RDKYKDLTGE | VEENERYAYE | WQRCLGSALN | VIKKANDTLN |

1200:

GISSSSVCTE | VIQSAQGMEY | LLGVVEVYRV | TKRVELGIKA | TAVCSEKLQQ |

1250:

LLKDIDKVWN | NLIGFMSLAT | LTPDENSLDF | SSCMLRPGIK | NAQELACGVC |

1300:

LLNVDSRSRK | EEKPAEEHPK | KAFNSETDSF | KLAYGGHQYH | ASCANFWINC |

1314:

VEPKPPGLVL | PDLL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000005279

String:

UniGene:

SMR:

KEGG:

MIM:

Uniprot:

FOR

ELISA Kit for Human Synergin gamma

ELISA Kit for Human Synergin gamma

ELISA Kit for Human Synergin gamma

CLIA Kit for Human Synergin gamma

CLIA Kit for Human Synergin gamma

CLIA Kit for Human Synergin gamma

Polyclonal Antibody for Human Synergin gamma

Polyclonal Antibody for Human Synergin gamma

Polyclonal Antibody for Human Synergin gamma

Monoclonal Antibody for Human Synergin gamma

Monoclonal Antibody for Human Synergin gamma

Monoclonal Antibody for Human Synergin gamma

Protein for Human Synergin gamma

Protein for Human Synergin gamma

Protein for Human Synergin gamma

R&D Technical Data

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Precision

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Recovery

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Linearity

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References

1.

"Large-scale proteomics analysis of the human kinome."
Oppermann F.S. , Gnad F. , Olsen J.V. , Hornberger R. , Greff Z. , Keri G. , Mann M. , Daub H.
Mol. Cell. Proteomics8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-752;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
2.

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-473; SER-752; SER-852 AND SER-855;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Leukemic T-cell.
3.

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-513 AND LYS-744;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
4.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-720; SER-752 AND SER-1075;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
5.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
6.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-473; SER-752 AND SER-1075;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
7.

"Gamma-synergin: an EH domain-containing protein that interacts with gamma-adaptin."
Page L.J. , Sowerby P.J. , Lui W.W.Y. , Robinson M.S.
J. Cell Biol.146:993-1004(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Brain.
8.

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Zody M.C. , Garber M. , Adams D.J. , Sharpe T. , Harrow J. , Lupski J.R. , Nicholson C. , Searle S.M. , Wilming L. , Young S.K. , Abouelleil A. , Allen N.R. , Bi W. , Bloom T. , Borowsky M.L. , Bugalter B.E. , Butler J. , Chang J.L. , more...
Nature440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2; 3; 5 AND 7)
tissue: Brain.
tissue: Lymph.
10.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 27-493 (ISOFORM 1)
tissue: Brain.
11.

"Adaptor gamma ear homology domain conserved in gamma-adaptin and GGA proteins that interact with gamma-synergin."
Takatsu H. , Yoshino K. , Nakayama K.
Biochem. Biophys. Res. Commun.271:719-725(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GGA1; GGA2; GGA3; AP1G1 AND AP1G2
12.

"EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking."
Mills I.G. , Praefcke G.J.K. , Vallis Y. , Peter B.J. , Olesen L.E. , Gallop J.L. , Butler P.J.G. , Evans P.R. , McMahon H.T.
J. Cell Biol.160:213-222(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DOMAIN;INTERACTION WITH AP1G1
13.

"Phosphoproteome of resting human platelets."
Zahedi R.P. , Lewandrowski U. , Wiesner J. , Wortelkamp S. , Moebius J. , Schuetz C. , Walter U. , Gambaryan S. , Sickmann A.
J. Proteome Res.7:526-534(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Platelet.
14.

"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-752;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
15.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-473; SER-752; SER-909; SER-919; SER-935 AND SER-1075;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
16.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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