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Index > Protein center > SYT6(Gene name) > Human
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  • SYT6 (Gene name),
  • Synaptotagmin-6 (Protein name ),  SYT6_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SYT6;
    Protein name:
    Synaptotagmin-6;
    Alternative:
    Synaptotagmin VI(SytVI);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer (isoform 1). Isoform 1 forms heterodimers with SytIII, SytV and SytX. Interacts with STX1A, STX1B and STX2; the interaction is Ca(2+)-dependent. Isoform 2 is not able to form homodimer and heterodimers.
    Function:
    May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. May mediate Ca(2+)-regulation of exocytosis in acrosomal reaction in sperm.
    Subcellular Location:
    Isoform 2 Cytoplasm cytosol Cell membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    510
    Sequence:
    50:
    MSGVWGAGGP | RCQEALAVLA | SLCRARPPPL | GLDVETCRSF | ELQPPERSPS | 
    100:
    AAGAGTSVSL | LAVVVIVCGV | ALVAVFLFLF | WKLCWMPWRN | KEASSPSSAN | 
    150:
    PPLEALQSPS | FRGNMADKLK | DPSTLGFLEA | AVKISHTSPD | IPAEVQMSVK | 
    200:
    EHIMRHTRLQ | RQTTEPASST | RHTSFKRHLP | RQMHVSSVDY | GNELPPAAEQ | 
    250:
    PTSIGRIKPE | LYKQKSVDGE | DAKSEATKSC | GKINFSLRYD | YETETLIVRI | 
    300:
    LKAFDLPAKD | FCGSSDPYVK | IYLLPDRKCK | LQTRVHRKTL | NPTFDENFHF | 
    350:
    PVPYEELADR | KLHLSVFDFD | RFSRHDMIGE | VILDNLFEAS | DLSRETSIWK | 
    400:
    DIQYATSESV | DLGEIMFSLC | YLPTAGRLTL | TVIKCRNLKA | MDITGYSDPY | 
    450:
    VKVSLLCDGR | RLKKKKTTIK | KNTLNPVYNE | AIIFDIPPEN | MDQVSLLISV | 
    500:
    MDYDRVGHNE | IIGVCRVGIT | AEGLGRDHWN | EMLAYPRKPI | AHWHSLVEVK | 
    510:
    KSFKEGNPRL | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    MIM:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Synaptotagmin-6
    ELISA Kit for Human Synaptotagmin-6
    ELISA Kit for Human Synaptotagmin-6
    CLIA Kit for Human Synaptotagmin-6
    CLIA Kit for Human Synaptotagmin-6
    CLIA Kit for Human Synaptotagmin-6
    Polyclonal Antibody for Human Synaptotagmin-6
    Polyclonal Antibody for Human Synaptotagmin-6
    Polyclonal Antibody for Human Synaptotagmin-6
    Monoclonal Antibody for Human Synaptotagmin-6
    Monoclonal Antibody for Human Synaptotagmin-6
    Monoclonal Antibody for Human Synaptotagmin-6
    Protein for Human Synaptotagmin-6
    Protein for Human Synaptotagmin-6
    Protein for Human Synaptotagmin-6

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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Teratocarcinoma.
    2. 2.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-216;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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