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Index > Protein center > Sytl4(Gene name) > Rat
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  • Sytl4 (Gene name),
  • Synaptotagmin-like protein 4 (Protein name ),  SYTL4_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Sytl4;
    Protein name:
    Synaptotagmin-like protein 4;
    Alternative:
    Granuphilin;Exophilin-2;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Part of a ternary complex containing STX1A and RAB27A. Can bind both dominant negative and dominant active mutants of RAB27A. Binds STXBP1, RAB3A, RAB8A and RAB27B.
    Function:
    Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phospholipids in a Ca(2+)-independent manner.
    Subcellular Location:
    Membrane Peripheral membrane protein Cytoplasmic vesicle secretory vesicle membrane Peripheral membrane protein Detected close to the plasma membrane and on secretory granules. In pancreas, interacts with insulin-containing vesicles.
    Protein Attributes:
    Sequence length:
    672
    Sequence:
    50:
    MSEILDLSFL | SEMERDLILS | VLQRDEELRK | ADEKRIRRLK | NELLEIKRKG | 
    100:
    AKRGSQHYSD | RTCARCQEGL | GRLISKSNTC | VGCNHLVCRE | CRVLESNGSW | 
    150:
    RCKVCSKEIE | LKKATGDWFY | DQKVNRFAYR | TGSDIIRMSL | RRKPAVNKRE | 
    200:
    TVGQSLLQQT | QMGDIWPGRR | IIQEQQKEQS | VLFEVPKLKS | GKSALEAESE | 
    250:
    SLDSYTADSD | STSRRDSLDK | SGLFPEWKKM | SAPKSQVEKE | IAPGNQNAVC | 
    300:
    GDEGDMIFKK | NTRKVLRPSE | YTKSVIDLRP | EDVAQESGIL | GDRSKSVPGL | 
    350:
    SVDMEDEEEE | EEDIDHLVKL | HRQKLARGSM | QSGSSMSTIG | SMMSLYSEAG | 
    400:
    DFGNVSVTGK | IAFSLKFEQK | TQTLVIHVKE | CHQLAYADEA | KKRSNPYVKT | 
    450:
    YLLPDKSRQG | KRKTSIKRDT | INPLYDETFR | YEISESLLAQ | RTLQFSVWHH | 
    500:
    GRFGRNTFLG | EAEVHMDSWK | LDKKLDHCLP | LHGKISTESS | PGLPAHKGEL | 
    550:
    VVSLKYIPAS | KLPVGGDRKK | SKGGEGGELQ | VWIKEAKNLT | AAKSGGTSDS | 
    600:
    FVKGYLLPMR | NKASKRKTPV | MKKTLNPHYN | HTFVYNGVRL | EDLQHMCLEL | 
    650:
    TVWDREPLAS | NDFLGGVRLG | VGTGISSGEV | VDWMDSTGEE | VSLWQKMRQY | 
    672:
    PGSWAEGTLQ | LRSSMVKQKL | GV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Synaptotagmin-like protein 4
    ELISA Kit for Rat Synaptotagmin-like protein 4
    ELISA Kit for Rat Synaptotagmin-like protein 4
    CLIA Kit for Rat Synaptotagmin-like protein 4
    CLIA Kit for Rat Synaptotagmin-like protein 4
    CLIA Kit for Rat Synaptotagmin-like protein 4
    Polyclonal Antibody for Rat Synaptotagmin-like protein 4
    Polyclonal Antibody for Rat Synaptotagmin-like protein 4
    Polyclonal Antibody for Rat Synaptotagmin-like protein 4
    Monoclonal Antibody for Rat Synaptotagmin-like protein 4
    Monoclonal Antibody for Rat Synaptotagmin-like protein 4
    Monoclonal Antibody for Rat Synaptotagmin-like protein 4
    Protein for Rat Synaptotagmin-like protein 4
    Protein for Rat Synaptotagmin-like protein 4
    Protein for Rat Synaptotagmin-like protein 4

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Pancreatic beta-cell protein granuphilin binds Rab3 and Munc-18 and controls exocytosis."
      Coppola T. , Frantz C. , Perret-Menoud V. , Gattesco S. , Hirling H. , Regazzi R.
      Mol. Biol. Cell13:1906-1915(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);MUTAGENESIS OF VAL-21 AND LEU-43;INTERACTION WITH RAB3A AND STXBP1;SUBCELLULAR LOCATION
      tissue: Insulinoma.
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