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Index > Protein center > SNCG(Gene name) > Human
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  • SNCG (Gene name),
  • Gamma-synuclein (Protein name ),  SYUG_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SNCG(BCSG1;PERSYN;PRSN);
    Protein name:
    Gamma-synuclein;
    Alternative:
    Persyn;Breast cancer-specific gene 1 protein;Synoretin(SR);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    May be a centrosome-associated protein.
    Function:
    Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway.
    Subcellular Location:
    Cytoplasm perinuclear region Cytoplasm cytoskeleton centrosome Cytoplasm cytoskeleton spindle Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle.
    Protein Attributes:
    Sequence length:
    127
    Sequence:
    50:
    MDVFKKGFSI | AKEGVVGAVE | KTKQGVTEAA | EKTKEGVMYV | GAKTKENVVQ | 
    100:
    SVTSVAEKTK | EQANAVSEAV | VSSVNTVATK | TVEEAENIAV | TSGVVRKEDL | 
    127:
    RPSAPQQEGE | ASKEKEEVAE | EAQSGGD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    String:
    KEGG:
    MIM:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Gamma-synuclein
    Cat.:
    E1271h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Gamma-synuclein
    Cat.:
    E1271m
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    Packing:
    96T
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    ELISA Kit for Human Gamma-synuclein
    Cat.:
    E1271r
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    Please sign in first.
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    96T
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    ELISA Kit for Human Gamma-synuclein
    Cat.:
    E1271b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Gamma-synuclein
    Cat.:
    U1271r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Gamma-synuclein
    Cat.:
    U1271m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Gamma-synuclein
    Cat.:
    U1271h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Gamma-synuclein
    Cat.:
    U1271b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Gamma-synuclein
    Cat.:
    P1271Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Gamma-synuclein
    Cat.:
    P1271Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Gamma-synuclein
    Polyclonal Antibody for Human Gamma-synuclein
    Cat.:
    P1271Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Gamma-synuclein
    Monoclonal Antibody for Human Gamma-synuclein
    Monoclonal Antibody for Human Gamma-synuclein
    Monoclonal Antibody for Human Gamma-synuclein
    Protein for Human Gamma-synuclein
    Protein for Human Gamma-synuclein
    Protein for Human Gamma-synuclein
    Protein for Human Gamma-synuclein

    R&D Technical Data
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    s

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    s
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤7.4%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤10.6%

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤3.9%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤7.7%

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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    Recovery was determined by spiking various levels of SYUG into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    96

    94-99

    Plasma

    98

    96-103

     

     

     

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

    Recovery was determined by spiking various levels of ACE into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    99

    91-103

    Plasma

    98

    93-106

     

     

     

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of SYUG and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    92-100%

    91-99%

    90-102%

    95-99%

    EDTA plasma(n=5)

    94-103%

    92-105%

    95-103%

    92-103%

    heparin plasma(n=5)

    93-105%

     

    90-106%

    93-104%

    94-102%

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

     

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    92-105%

    90-101%

    95-105%

    92-109%

    EDTA plasma(n=5)

    89-95%

    93105%

    89-94%

    90-106%

    heparin plasma(n=5)

    93-104%

     

    94-110%

    101-111%

    91-110%

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Identification of a breast cancer-specific gene, BCSG1, by direct differential cDNA sequencing."
      Ji H. , Liu Y.E. , Jia T. , Wang M. , Liu J. , Xiao G. , Joseph B.K. , Rosen C. , Shi Y.E.
      Cancer Res.57:759-764(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Mammary cancer.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
    3. 3.
      "Identification, localization and characterization of the human gamma-synuclein gene."
      Lavedan C. , Leroy E. , Dehejia A. , Buchholtz S. , Dutra A. , Nussbaum R.L. , Polymeropoulos M.H.
      Hum. Genet.103:106-112(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT VAL-110
    4. 4.
      Han C. , Zhang B. , Peng X. , Yuan J. , Qiang B.
      Submitted (2001-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT VAL-110
      tissue: Colon.
    6. 6.
      "Synucleins are a novel class of substrates for G protein-coupled receptor kinases."
      Pronin A.N. , Morris A.J. , Surguchov A. , Benovic J.L.
      J. Biol. Chem.275:26515-26522(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-124 BY BARK1; CAMK2 AND CK2
    7. 7.
      "Gamma synuclein: subcellular localization in neuronal and non-neuronal cells and effect on signal transduction."
      Surguchov A. , Palazzo R.E. , Surgucheva I.
      Cell Motil. Cytoskeleton49:218-228(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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