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Index > Protein center > Taok1(Gene name) > Mouse
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  • Taok1 (Gene name),
  • Serine/threonine-protein kinase TAO1 (Protein name ),  TAOK1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Taok1(Kiaa1361);
    Protein name:
    Serine/threonine-protein kinase TAO1;
    Alternative:
    Thousand and one amino acid protein 1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Self-associates. Interacts with MAP2K3. Interacts with SPRED1 and TESK1. Interacts with MAP3K7.
    Function:
    Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6. Acts as a regulator of cytoskeleton stability by phosphorylating 'Thr-208' of MARK2, leading to activate MARK2 kinase activity and subsequent phosphorylation and detachment of MAPT/TAU from microtubules. Also acts as a regulator of apoptosis: regulates apoptotic morphological changes, including cell contraction, membrane blebbing and apoptotic bodies formation via activation of the MAPK8/JNK cascade.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    1001
    Sequence:
    50:
    MPSTNRAGSL | KDPEIAELFF | KEDPEKLFTD | LREIGHGSFG | AVYFARDVRT | 
    100:
    NEVVAIKKMS | YSGKQSTEKW | QDIIKEVKFL | QRIKHPNSIE | YKGCYLREHT | 
    150:
    AWLVMEYCLG | SASDLLEVHK | KPLQEVEIAA | ITHGALQGLA | YLHSHTMIHR | 
    200:
    DIKAGNILLT | EPGQVKLADF | GSASMASPAN | SFVGTPYWMA | PEVILAMDEG | 
    250:
    QYDGKVDVWS | LGITCIELAE | RKPPLFNMNA | MSALYHIAQN | ESPTLQSNEW | 
    300:
    SDYFRNFVDS | CLQKIPQDRP | TSEELLKHMF | VLRERPETVL | IDLIQRTKDA | 
    350:
    VRELDNLQYR | KMKKLLFQEA | HNGPAVEAQE | EEEEQDHGVG | RTGTVNSVGS | 
    400:
    NQSIPSMSIS | ASSQSSSVNS | LPDASDDKSE | LDMMEGDHTV | MSNSSVIHLK | 
    450:
    PEEENYQEEG | DPRTRASDPQ | SPPQVSRHKS | HYRNREHFAT | IRTASLVTRQ | 
    500:
    MQEHEQDSEL | REQMSGYKRM | RRQHQKQLMT | LENKLKAEMD | EHRLRLDKDL | 
    550:
    ETQRNNFAAE | MEKLIKKHQA | AMEKEAKVMA | NEEKKFQQHI | QAQQKKELNS | 
    600:
    FLESQKREYK | LRKEQLKEEL | NENQSTPKKE | KQEWLSKQKE | NIQHFQAEEE | 
    650:
    ANLLRRQRQY | LELECRRFKR | RMLLGRHNLE | QDLVREELNK | RQTQKDLEHA | 
    700:
    MLLRQHESMQ | ELEFRHLNTI | QKMRCELIRL | QHQTELTNQL | EYNKRREREL | 
    750:
    RRKHVMEVRQ | QPKSLKSKEL | QIKKQFQDTC | KIQTRQYKAL | RNHLLETTPK | 
    800:
    SEHKAVLKRL | KEEQTRKLAI | LAEQYDHSIN | EMLSTQALRL | DEAQEAECQV | 
    850:
    LKMQLQQELE | LLNAYQSKIK | MQAEAQHDRE | LRELEQRVSL | RRALLEQKIE | 
    900:
    EEMLALQNER | TERIRSLLER | QAREIEAFDS | ESMRLGFSNM | VLSNLSPEAF | 
    950:
    SHSYPGASSW | SHNPTGGPGP | HWGHPMGGTP | QAWGHPMQGG | PQPWGHPSGP | 
    1000:
    MQGVPRGSSM | GVRNSPQALR | RTASGGRTEQ | GMSRSTSVTS | QISNGSHMSY | 
    1001:
    T
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Serine/threonine-protein kinase TAO1
    Cat.:
    E2238h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse Serine/threonine-protein kinase TAO1
    Cat.:
    E2238r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Serine/threonine-protein kinase TAO1
    Cat.:
    E2238m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Serine/threonine-protein kinase TAO1
    Cat.:
    U2238m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Serine/threonine-protein kinase TAO1
    Cat.:
    U2238r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Serine/threonine-protein kinase TAO1
    Cat.:
    U2238h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Serine/threonine-protein kinase TAO1
    Cat.:
    P2238Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Serine/threonine-protein kinase TAO1
    Cat.:
    P2238Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Serine/threonine-protein kinase TAO1
    Cat.:
    P2238Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Serine/threonine-protein kinase TAO1
    Monoclonal Antibody for Mouse Serine/threonine-protein kinase TAO1
    Monoclonal Antibody for Mouse Serine/threonine-protein kinase TAO1
    Protein for Mouse Serine/threonine-protein kinase TAO1
    Protein for Mouse Serine/threonine-protein kinase TAO1
    Protein for Mouse Serine/threonine-protein kinase TAO1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 437-1001
      strain: FVB/N.
      tissue: Mammary gland.
      tissue: Thymus.
    3. 3.
      "Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Seino S. , Nishimura M. , Kaisho T. , Hoshino K. , Kitamura H. , Nagase T. , Ohara O. , Koga H.
      DNA Res.11:205-218(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 657-1001
      tissue: Brain.
    4. 4.
      "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
      Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
      Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
    5. 5.
      "Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations."
      Munton R.P. , Tweedie-Cullen R. , Livingstone-Zatchej M. , Weinandy F. , Waidelich M. , Longo D. , Gehrig P. , Potthast F. , Rutishauser D. , Gerrits B. , Panse C. , Schlapbach R. , Mansuy I.M.
      Mol. Cell. Proteomics6:283-293(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain cortex.
    6. 6.
      "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
      Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-421;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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