Protein name:
Carabin ;
Alternative:
TBC1 domain family member 10C ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with both calcineurin and HRAS.
Function:
Inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. Acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras.
Subcellular Location:
N/A
Protein Attributes:
50:
MAQALGEDLV | QPPELQDDSS | SLGSDSELSG | PGPYRQADRY | GFIGGSSAEP |
100:
GPGHPPADLI | RQREMKWVEM | TSHWEKTMSR | RYKKVKMQCR | KGIPSALRAR |
150:
CWPLLCGAHV | CQKNSPGTYQ | ELAEAPGDPQ | WMETIGRDLH | RQFPLHEMFV |
200:
SPQGHGQQGL | LQVLKAYTLY | RPEQGYCQAQ | GPVAAVLLMH | LPPEEAFWCL |
250:
VQICEVYLPG | YYGPHMEAVR | LDAEVFMALL | RRLLPHVHKH | LQQVGVGPLL |
300:
YLPEWFLCLF | ARSLPFPTVL | RVWDAFLSEG | ARVLFRVGLT | LVRLALGTAE |
350:
QRGACPGLLE | TLGALRAIPP | AQLQEEAFMS | QVHSVVLSER | DLQREIKAQL |
400:
AQLPDSAPGP | PPRPQVRLAG | AQAIFEAQQL | AGVRRGAKPE | VPRIVVQPPE |
446:
EPRPPRRKPQ | TRGKTFHGLL | TRARGPPIEG | PPRPQRGSTS | FLDTRF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Carabin
ELISA Kit for Human Carabin
CLIA Kit for Human Carabin
CLIA Kit for Human Carabin
Polyclonal Antibody for Human Carabin
Polyclonal Antibody for Human Carabin
Monoclonal Antibody for Human Carabin
Monoclonal Antibody for Human Carabin
Protein for Human Carabin
Protein for Human Carabin
R&D Technical Data
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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References
1.
"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D.
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Noguchi H.
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Totoki Y.
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Kim D.-W.
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Cuomo C.A.
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Nicol R.
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Park H.-S.
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Seaman C.
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Sougnez C.
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Yang X.
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Zimmer A.R.
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Zody M.C.
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Birren B.W.
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Nusbaum C.
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Fujiyama A.
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Hattori M.
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Rogers J.
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Lander E.S.
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Sakaki Y.
more...
Nature440:497-500(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
2.
Mural R.J.
,
Istrail S.
,
Sutton G.
,
Florea L.
,
Halpern A.L.
,
Mobarry C.M.
,
Lippert R.
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Walenz B.
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Shatkay H.
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Dew I.
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Miller J.R.
,
Flanigan M.J.
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Edwards N.J.
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Bolanos R.
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Fasulo D.
,
Halldorsson B.V.
,
Hannenhalli S.
,
Turner R.
,
Yooseph S.
,
Lu F.
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Nusskern D.R.
,
Shue B.C.
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Zheng X.H.
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Zhong F.
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Delcher A.L.
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Huson D.H.
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Kravitz S.A.
,
Mouchard L.
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Reinert K.
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Clark A.G.
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Waterman M.S.
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more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue :
Brain .
tissue :
Leukocyte .
tissue :
Pancreas .
4.
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Cited for : FUNCTION;TISSUE SPECIFICITY;INTERACTION WITH CALCINEURIN AND HRAS;MUTAGENESIS OF ARG-141
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Leukemic T-cell .