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Index > Protein center > TBC1D10C(Gene name) > Human
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  • TBC1D10C (Gene name),
  • Carabin (Protein name ),  TB10C_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TBC1D10C;
    Protein name:
    Carabin;
    Alternative:
    TBC1 domain family member 10C;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with both calcineurin and HRAS.
    Function:
    Inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. Acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    446
    Sequence:
    50:
    MAQALGEDLV | QPPELQDDSS | SLGSDSELSG | PGPYRQADRY | GFIGGSSAEP | 
    100:
    GPGHPPADLI | RQREMKWVEM | TSHWEKTMSR | RYKKVKMQCR | KGIPSALRAR | 
    150:
    CWPLLCGAHV | CQKNSPGTYQ | ELAEAPGDPQ | WMETIGRDLH | RQFPLHEMFV | 
    200:
    SPQGHGQQGL | LQVLKAYTLY | RPEQGYCQAQ | GPVAAVLLMH | LPPEEAFWCL | 
    250:
    VQICEVYLPG | YYGPHMEAVR | LDAEVFMALL | RRLLPHVHKH | LQQVGVGPLL | 
    300:
    YLPEWFLCLF | ARSLPFPTVL | RVWDAFLSEG | ARVLFRVGLT | LVRLALGTAE | 
    350:
    QRGACPGLLE | TLGALRAIPP | AQLQEEAFMS | QVHSVVLSER | DLQREIKAQL | 
    400:
    AQLPDSAPGP | PPRPQVRLAG | AQAIFEAQQL | AGVRRGAKPE | VPRIVVQPPE | 
    446:
    EPRPPRRKPQ | TRGKTFHGLL | TRARGPPIEG | PPRPQRGSTS | FLDTRF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    UniGene:
    SMR:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Carabin
    ELISA Kit for Human Carabin
    CLIA Kit for Human Carabin
    CLIA Kit for Human Carabin
    Polyclonal Antibody for Human Carabin
    Polyclonal Antibody for Human Carabin
    Monoclonal Antibody for Human Carabin
    Monoclonal Antibody for Human Carabin
    Protein for Human Carabin
    Protein for Human Carabin

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Brain.
      tissue: Leukocyte.
      tissue: Pancreas.
    4. 4.
      "Feedback inhibition of calcineurin and Ras by a dual inhibitory protein Carabin."
      Pan F. , Sun L. , Kardian D.B. , Whartenby K.A. , Pardoll D.M. , Liu J.O.
      Nature445:433-436(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;INTERACTION WITH CALCINEURIN AND HRAS;MUTAGENESIS OF ARG-141
    5. 5.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
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