Gene name:
PTGES3 (P23;TEBP) ;
Protein name:
Prostaglandin E synthase 3 ;
Alternative:
Hsp90 co-chaperone ;Cytosolic prostaglandin E2 synthase (cPGES) ;Telomerase-binding protein p23 ;Progesterone receptor complex p23 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Binds to the progesterone receptor. Interacts with TERT; the interaction, together with HSP90AA1, is required for correct assembly and stabilization of the telomerase holoenzyme complex.
Function:
Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MQPASAKWYD | RRDYVFIEFC | VEDSKDVNVN | FEKSKLTFSC | LGGSDNFKHL |
100:
NEIDLFHCID | PNDSKHKRTD | RSILCCLRKG | ESGQSWPRLT | KERAKLNWLS |
150:
VDFNNWKDWE | DDSDEDMSNF | DRFSEMMNNM | GGDEDVDLPE | VDGADDDSQD |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Chicken
Mouse
Rat
Human
Bovine
ELISA Kit for Human Prostaglandin E synthase 3
ELISA Kit for Human Prostaglandin E synthase 3
ELISA Kit for Human Prostaglandin E synthase 3
ELISA Kit for Human Prostaglandin E synthase 3
ELISA Kit for Human Prostaglandin E synthase 3
CLIA Kit for Human Prostaglandin E synthase 3
CLIA Kit for Human Prostaglandin E synthase 3
CLIA Kit for Human Prostaglandin E synthase 3
CLIA Kit for Human Prostaglandin E synthase 3
CLIA Kit for Human Prostaglandin E synthase 3
Polyclonal Antibody for Human Prostaglandin E synthase 3
Polyclonal Antibody for Human Prostaglandin E synthase 3
Polyclonal Antibody for Human Prostaglandin E synthase 3
Polyclonal Antibody for Human Prostaglandin E synthase 3
Polyclonal Antibody for Human Prostaglandin E synthase 3
Monoclonal Antibody for Human Prostaglandin E synthase 3
Monoclonal Antibody for Human Prostaglandin E synthase 3
Monoclonal Antibody for Human Prostaglandin E synthase 3
Monoclonal Antibody for Human Prostaglandin E synthase 3
Monoclonal Antibody for Human Prostaglandin E synthase 3
Protein for Human Prostaglandin E synthase 3
Protein for Human Prostaglandin E synthase 3
Protein for Human Prostaglandin E synthase 3
Protein for Human Prostaglandin E synthase 3
Protein for Human Prostaglandin E synthase 3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Testis .
2.
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
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Nat. Genet.36:40-45(2004)
[
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[
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2; 3 AND 4)
tissue :
Caudate nucleus .
3.
"The finished DNA sequence of human chromosome 12."
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.
Mural R.J.
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more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Lung .
tissue :
Urinary bladder .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 13-65; 72-88 AND 96-122;PHOSPHORYLATION AT SER-113;IDENTIFICATION BY MASS SPECTROMETRY
tissue :
Embryonic kidney .
7.
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Cited for : INTERACTION WITH TERT;FUNCTION AS A CO-CHAPERONE IN TELOMERASE HOLOENZYME ASSEMBLY
8.
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Cited for : FUNCTION AS A CHAPERONE
9.
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Cited for : FUNCTION AS A PROSTAGLANDIN SYNTHASE;BIOPHYSICOCHEMICAL PROPERTIES;CATALYTIC ACTIVITY;PATHWAY
10.
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Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113; SER-118; SER-148 AND SER-151;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
11.
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Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Pituitary .
12.
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Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Prostate cancer .
13.
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Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
T-cell .
14.
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Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Platelet .
15.
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Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113; SER-148 AND SER-151;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
16.
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Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113; SER-148 AND SER-151;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
17.
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Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
18.
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Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
19.
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Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
20.
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Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Leukemic T-cell .
21.
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Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-33;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
22.
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V.
,
Vermeulen M.
,
Santamaria A.
,
Kumar C.
,
Miller M.L.
,
Jensen L.J.
,
Gnad F.
,
Cox J.
,
Jensen T.S.
,
Nigg E.A.
,
Brunak S.
,
Mann M.
Sci. Signal.3:RA3-RA3(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113 AND SER-118;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
23.
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Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
24.
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Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-113;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
25.
"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P.
,
Lasa M.
,
Polevoda B.
,
Gazquez C.
,
Elosegui-Artola A.
,
Kim D.S.
,
De Juan-Pardo E.
,
Demeyer K.
,
Hole K.
,
Larrea E.
,
Timmerman E.
,
Prieto J.
,
Arnesen T.
,
Sherman F.
,
Gevaert K.
,
Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
26.
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Cited for : FUNCTION;INTERACTION WITH EGLN1
27.
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Cited for : X-RAY CRYSTALLOGRAPHY (2.49 ANGSTROMS) OF 1-125