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Index > Protein center > Tnc(Gene name) > Mouse
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  • Tnc (Gene name),
  • Tenascin (Protein name ),  TENA_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Tnc(Hxb);
    Protein name:
    Tenascin(TN);
    Alternative:
    Tenascin-C(TN-C);Hexabrachion;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homohexamer; disulfide-linked. A homotrimer may be formed in the triple coiled-coil region and may be stabilized by disulfide rings at both ends. Two of such half-hexabrachions may be disulfide linked within the central globule. Interacts with CSPG4.
    Function:
    Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth when provided to neurons in culture. May play a role in supporting the growth of epithelial tumors. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
    Subcellular Location:
    Secreted extracellular space extracellular matrix
    Protein Attributes:
    Sequence length:
    2110
    Sequence:
    50:
    MGAVTWLLPG | IFLALFALTP | EGGVLKKIIR | HKRESGLNMT | LPEENQPVVF | 
    100:
    NHIYNIKLPM | GSQCSVDLES | ASGEKDLTPT | PESSGSFQEH | TVDGENQIVF | 
    150:
    THRINIPRRA | CGCAAAPDVK | ELLSRLEELE | LLVSSLREQC | TMGTGCCLQP | 
    200:
    AEGRLDTRPF | CSGRGNFSAE | GCGCVCEPGW | KGPNCSEPDC | PGNCNLRGQC | 
    250:
    LDGQCICDEG | FTGEDCSQLA | CPNDCNDQGR | CVNGVCVCFE | GYAGPDCGLE | 
    300:
    VCPVPCSEEH | GMCVDGRCVC | KDGFAGEDCN | EPLCLNNCYN | RGRCVENECV | 
    350:
    CDEGFTGEDC | SELICPNDCF | DRGRCINGTC | YCEEGFTGED | CGELTCPNDC | 
    400:
    QGRGQCEEGQ | CVCNEGFAGA | DCSEKRCPAD | CHHRGRCLNG | QCECDDGFTG | 
    450:
    ADCGDLQCPN | GCSGHGRCVN | GQCVCDEGYT | GEDCSQRRCP | NDCHNRGLCV | 
    500:
    QGKCICEQGF | KGFDCSEMSC | PNDCHQHGRC | VNGMCICDDD | YTGEDCRDRR | 
    550:
    CPRDCSQRGR | CVDGQCICED | GFTGPDCAEL | SCPSDCHGHG | RCVNGQCICH | 
    600:
    EGFTGKDCKE | QRCPSDCHGQ | GRCEDGQCIC | HEGFTGLDCG | QRSCPNDCSN | 
    650:
    QGQCVSGRCI | CNEGYTGIDC | SEVSPPKDLI | VTEVTEETVN | LAWDNEMRVT | 
    700:
    EYLIMYTPTH | ADGLEMQFRV | PGDQTSTTIR | ELEPGVEYFI | RVFAILENKR | 
    750:
    SIPVSARVAT | YLPAPEGLKF | KSIKETSVEV | EWDPLDIAFE | TWEIIFRNMN | 
    800:
    KEDEGEITKS | LRRPETSYRQ | TGLAPGQEYE | ISLHIVKNNT | RGPGLKKVTT | 
    850:
    TRLDAPSHIE | VKDVTDTTAL | ITWFKPLAEI | DSIELSYGIK | DVPGDRTTID | 
    900:
    LTHEDNQYSI | GNLRPDTEYE | VSLISRRVDM | ASNPAKETFI | TGLDAPRNLR | 
    950:
    RVSQTDNSIT | LEWRNVKADI | DSYRIKYAPI | SGGDHAEIDV | PKSQQATTKT | 
    1000:
    TLTGLRPGTE | YGIGVSAVKG | DKESDPATIN | AATEIDAPKD | LRVSETTQDS | 
    1050:
    LTFFWTTPLA | KFDRYRLNYS | LPTGQSMEVQ | LPKDATSHVL | TDLEPGQEYT | 
    1100:
    VLLIAEKGRH | KSKPARVKAS | TEEVPSLENL | TVTEAGWDGL | RLNWTADDLA | 
    1150:
    YEYFVIQVQE | ANNVETAHNF | TVPGNLRAAD | IPGLKVATSY | RVSIYGVARG | 
    1200:
    YRTPVLSAET | STGTTPNLGE | VTVAEVGWDA | LTLNWTAPEG | AYKNFFIQVL | 
    1250:
    EADTTQTVQN | LTVPGGLRSV | DLPGLKAATR | YYITLRGVTQ | DFGTAPLSVE | 
    1300:
    VLTEDLPQLG | GLSVTEVSWD | GLTLNWTTDD | LAYKHFVVQV | QEANNVEAAQ | 
    1350:
    NLTVPGSLRA | VDIPGLKADT | PYRVSIYGVI | QGYRTPMLST | DVSTAREPEI | 
    1400:
    GNLNVSDVTP | KSFNLSWTAT | DGIFDMFTIE | IIDSNRLLQT | AEHNISGAER | 
    1450:
    TAHISGLPPS | TDFIVYLSGI | APSIRTKTIS | TTATTEALPL | LENLTISDTN | 
    1500:
    PYGFTVSWTA | SENAFDSFLV | TVVDSGKLLD | PQEFTLSGTQ | RKLELRGLIT | 
    1550:
    GIGYEVLVSG | FTQGHQTKPL | RAETITEAEP | EVDNLLVSDA | TPDGFRLSWT | 
    1600:
    ADEGIFDSFV | IRIRDTKKQS | EPQEISLPSP | ERTRDITGLR | EATEYEIELY | 
    1650:
    GISRGRRSQP | VSAIATTAMG | SPKEIMFSDI | TENAATVSWR | APTAQVESFR | 
    1700:
    ITYVPMTGGA | PSMVTVDGTD | TETRLVKLTP | GVEYRVSVIA | MKGFEESDPV | 
    1750:
    SGTLITALDG | PSGLLIANIT | DSEALAMWQP | AIATVDSYVI | SYTGERVPEV | 
    1800:
    TRTVSGNTVE | YELHDLEPAT | EYILSIFAEK | GQQKSSTIAT | KFTTDLDSPR | 
    1850:
    EFTATEVQSE | TALLTWRPPR | ASVTGYLLVY | ESVDGTVKEV | IVGPDTTSYS | 
    1900:
    LADLSPSTHY | SARIQALSGS | LRSKLIQTIF | TTIGLLYPFP | RDCSQAMLNG | 
    1950:
    DTTSGLYTIY | INGDKTQALE | VYCDMTSDGG | GWIVFLRRKN | GREDFYRNWK | 
    2000:
    AYAAGFGDRR | EEFWLGLDNL | SKITAQGQYE | LRVDLQDHGE | SAYAVYDRFS | 
    2050:
    VGDAKSRYKL | KVEGYSGTAG | DSMNYHNGRS | FSTYDKDTDS | AITNCALSYK | 
    2100:
    GAFWYKNCHR | VNLMGRYGDN | NHSQGVNWFH | WKGHEYSIQF | AEMKLRPSNF | 
    2110:
    RNLEGRRKRA | 
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    KEGG:
    SMR:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse TN
    Cat.:
    E1975h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse TN
    Cat.:
    E1975m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse TN
    Cat.:
    E1975p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse TN
    Cat.:
    E1975c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse TN
    Cat.:
    U1975m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse TN
    Cat.:
    U1975c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse TN
    Cat.:
    U1975h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse TN
    Cat.:
    U1975p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse TN
    Cat.:
    P1975Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse TN
    Cat.:
    P1975Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse TN
    Polyclonal Antibody for Mouse TN
    Monoclonal Antibody for Mouse TN
    Monoclonal Antibody for Mouse TN
    Monoclonal Antibody for Mouse TN
    Monoclonal Antibody for Mouse TN
    Protein for Mouse TN
    Protein for Mouse TN
    Protein for Mouse TN
    Protein for Mouse TN

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    Precision
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    References
    1. 1.
      "Murine tenascin: cDNA cloning, structure and temporal expression of isoforms."
      Saga Y. , Tsukamoto T. , Jing N. , Kusakabe M. , Sakakura T.
      Gene104:177-185(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 3; 4 AND 5);TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
      strain: GRS.
      tissue: Mammary tumor.
    2. 2.
      "Amino acid sequence of mouse tenascin and differential expression of two tenascin isoforms during embryogenesis."
      Weller A. , Beck S. , Ekblom P.
      J. Cell Biol.112:355-362(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 5);DEVELOPMENTAL STAGE;GLYCOSYLATION
      strain: NMRI X 129.
      tissue: Embryo.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      "Enhanced novelty-induced activity, reduced anxiety, delayed resynchronization to daylight reversal and weaker muscle strength in tenascin-C-deficient mice."
      Morellini F. , Schachner M.
      Eur. J. Neurosci.23:1255-1268(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
    5. 5.
      "Proteome-wide characterization of N-glycosylation events by diagonal chromatography."
      Ghesquiere B. , Van Damme J. , Martens L. , Vandekerckhove J. , Gevaert K.
      J. Proteome Res.5:2438-2447(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-1394
      strain: C57BL/6.
      tissue: Plasma.
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