TEP1 ELISA Kit for Human(Homo sapiens) | EIAab.comTEP1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > TEP1(Gene name) > Human

TEP1 (Gene name),

Telomerase protein component 1 (Protein name ), TEP1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

TEP1(TLP1;TP1);

Protein name:

Telomerase protein component 1;

Alternative:

p240;Telomerase-associated protein 1(Telomerase protein 1);p80 telomerase homolog;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Component of the telomerase holoenzyme complex at least composed of TERT, DKC1, WRAP53/TCAB1, NOP10, NHP2, GAR1, TEP1, EST1A, POT1 and a telomerase RNA template component (TERC). Component of the vault ribonucleoprotein particle, at least composed of MVP, PARP4 and one or more vault RNAs (vRNAs). Binds to VAULTRC1, VAULTRC2 and VAULTRC4/hvg4 vRNAs.

Function:

Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC.

Subcellular Location:

Nucleus Chromosome telomere

Protein Attributes:

Sequence length:

2627

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2627:

EPWLGANSTL | QLAVGDVQGN | VYFLNWE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF05386

UniGene:

Hs.508835

STRING:

9606.ENSP00000262715

Pfam:

PF13271

String:

Q99973

SMR:

Q99973

KEGG:

hsa:7011

MIM:

601686

Uniprot:

Q99973

FOR

ELISA Kit for Human Telomerase protein component 1

Cat.:

E0558h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Human Telomerase protein component 1

Cat.:

E0558r

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MSDS:

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Packing:

96T

ELISA Kit for Human Telomerase protein component 1

Cat.:

E0558m

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MSDS:

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Packing:

96T

CLIA Kit for Human Telomerase protein component 1

Cat.:

U0558h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Telomerase protein component 1

Cat.:

U0558m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Telomerase protein component 1

Cat.:

U0558r

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Telomerase protein component 1

Cat.:

P0558Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Telomerase protein component 1

Cat.:

P0558Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Telomerase protein component 1

Cat.:

P0558Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Telomerase protein component 1

Protein for Human Telomerase protein component 1

Cat.:

R0558h

Price:

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Packing:

1mg

Purity:

>90%

Protein for Human Telomerase protein component 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A mammalian telomerase-associated protein."
Harrington L. , McPhail T. , Mar V. , Zhou W. , Oulton R. , Bass M.B. , Arruda I. , Robinson M.O.
Science275:973-977(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY;VARIANTS PRO-116; GLY-553; CYS-1055; GLN-1155 AND PRO-1195
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Cerebellum.
3.

"The full-ORF clone resource of the German cDNA consortium."
Bechtel S. , Rosenfelder H. , Duda A. , Schmidt C.P. , Ernst U. , Wellenreuther R. , Mehrle A. , Schuster C. , Bahr A. , Bloecker H. , Heubner D. , Hoerlein A. , Michel G. , Wedler H. , Koehrer K. , Ottenwaelder B. , Poustka A. , Wiemann S. , more...
BMC Genomics8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2288-2627 (ISOFORM 2)
tissue: Salivary gland.
4.

"Human telomerase contains evolutionarily conserved catalytic and structural subunits."
Harrington L. , Zhou W. , McPhail T. , Oulton R. , Yeung D.S. , Mar V. , Bass M.B. , Robinson M.O.
Genes Dev.11:3109-3115(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE TELOMERASE RIBONUCLEOPROTEIN COMPLEX
5.

"Vaults and telomerase share a common subunit, TEP1."
Kickhoefer V.A. , Stephen A.G. , Harrington L. , Robinson M.O. , Rome L.H.
J. Biol. Chem.274:32712-32717(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE VAULTS RIBONUCLEOPROTEIN PARTICLE;RNA-BINDING
6.

"Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 binding."
Beattie T.L. , Zhou W. , Robinson M.O. , Harrington L.
Mol. Biol. Cell11:3329-3340(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE TELOMERASE RIBONUCLEOPROTEIN COMPLEX
7.

"A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis."
Venteicher A.S. , Abreu E.B. , Meng Z. , McCann K.E. , Terns R.M. , Veenstra T.D. , Terns M.P. , Artandi S.E.
Science323:644-648(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE TELOMERASE HOLOENZYME COMPLEX

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