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Index > Protein center > TGFB1(Gene name) > Pig
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  • TGFB1 (Gene name),
  • Transforming growth factor beta-1 (Protein name ),  TGFB1_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TGFB1;
    Protein name:
    Transforming growth factor beta-1(TGF-beta-1);
    Alternative:

    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    The inactive form consists of a TGFB1 homodimer non-covalently linked to a latency-associated peptide (LAP) homodimer. The inactive complex can contain a latent TGFB1-binding protein. The active form is a homodimer of mature TGFB1; disulfide-linked. Heterodimers of TGFB1/TGFB2 have been found in bone. Interacts with CD109 and DPT. Interacts with ASPN.
    Function:
    Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
    Subcellular Location:
    Secreted extracellular space extracellular matrix
    Protein Attributes:
    Sequence length:
    390
    Sequence:
    50:
    MPPSGLRLLP | LLLPLLWLLV | LTPGRPAAGL | STCKTIDMEL | VKRKRIEAIR | 
    100:
    GQILSKLRLA | SPPSQGDVPP | GPLPEAVLAL | YNSTRDRVAG | ESVEPEPEPE | 
    150:
    ADYYAKEVTR | VLMLESGNQI | YDKFKGTPHS | LYMLFNTSEL | REAVPEPVLL | 
    200:
    SRAELRLLRL | KLKVEQHVEL | YQKYSNDSWR | YLSNRLLAPS | DSPEWLSFDV | 
    250:
    TGVVRQWLTR | REAIEGFRLS | AHCSCDSKDN | TLHVEINGFN | SGRRGDLATI | 
    300:
    HGMNRPFLLL | MATPLERAQH | LHSSRHRRAL | DTNYCFSSTE | KNCCVRQLYI | 
    350:
    DFRKDLGWKW | IHEPKGYHAN | FCLGPCPYIW | SLDTQYSKVL | ALYNQHNPGA | 
    390:
    SAAPCCVPQA | LEPLPIVYYV | GRKPKVEQLS | NMIVRSCKCS | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Pig TGF-beta-1
    Cat.:
    E0124b
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Pig TGF-beta-1
    Cat.:
    E0124h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Pig TGF-beta-1
    Cat.:
    E0124m
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Pig TGF-beta-1
    Cat.:
    E0124p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig TGF-beta-1
    Cat.:
    E0124d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Pig TGF-beta-1
    Cat.:
    E0124c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig TGF-beta-1
    Cat.:
    E0124r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig TGF-beta-1
    Cat.:
    U0124d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig TGF-beta-1
    Cat.:
    U0124c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig TGF-beta-1
    Cat.:
    U0124r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig TGF-beta-1
    Cat.:
    U0124m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig TGF-beta-1
    Cat.:
    U0124h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig TGF-beta-1
    Cat.:
    U0124p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig TGF-beta-1
    Cat.:
    U0124b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Pig TGF-beta-1
    Cat.:
    P0124Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig TGF-beta-1
    Cat.:
    P0124Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig TGF-beta-1
    Polyclonal Antibody for Pig TGF-beta-1
    Cat.:
    P0124Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig TGF-beta-1
    Polyclonal Antibody for Pig TGF-beta-1
    Polyclonal Antibody for Pig TGF-beta-1
    Monoclonal Antibody for Pig TGF-beta-1
    Monoclonal Antibody for Pig TGF-beta-1
    Monoclonal Antibody for Pig TGF-beta-1
    Monoclonal Antibody for Pig TGF-beta-1
    Monoclonal Antibody for Pig TGF-beta-1
    Monoclonal Antibody for Pig TGF-beta-1
    Monoclonal Antibody for Pig TGF-beta-1
    Protein for Pig TGF-beta-1
    Protein for Pig TGF-beta-1
    Protein for Pig TGF-beta-1
    Protein for Pig TGF-beta-1
    Protein for Pig TGF-beta-1
    Protein for Pig TGF-beta-1
    Cat.:
    R0124h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Pig TGF-beta-1
    Cat.:
    R0124m
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%

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    References
    1. 1.
      "Sequence of the porcine transforming growth factor-beta precursor."
      Derynck R. , Rhee L.
      Nucleic Acids Res.15:3187-3187(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Ovary.
    2. 2.
      "cDNA cloning of porcine transforming growth factor-beta 1 mRNAs. Evidence for alternate splicing and polyadenylation."
      Kondaiah P. , van Obberghen-Schilling E. , Ludwig R.L. , Dhar R. , Sporn M.B. , Roberts A.B.
      J. Biol. Chem.263:18313-18317(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT VAL-114
      strain: Miniature swine.
    3. 3.
      "Nucleotide sequence of chicken transforming growth factor-beta 1 (TGF-beta 1)."
      Jakowlew S.B. , Dillard P.J. , Sporn M.B. , Roberts A.B.
      Nucleic Acids Res.16:8730-8730(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT VAL-114
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SHOWS THAT SEQUENCE DESCRIBED IN PUBMED:3166520 ORIGINATES FROM PIG
    5. 5.
      "Polymorphism in the porcine transforming growth factor-beta1 gene."
      Wimmers K. , Chomdej S. , Ponsuksili S. , Schellander K.
      Anim. Genet.33:234-235(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT VAL-114
    6. 6.
      "The transforming growth factor-beta system, a complex pattern of cross-reactive ligands and receptors."
      Cheifetz S. , Weatherbee J.A. , Tsang M.L.S. , Anderson J.K. , Mole J.E. , Lucas R. , Massague J.
      Cell48:409-415(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 279-322
    7. 7.
      "Latent TGF-beta structure and activation."
      Shi M. , Zhu J. , Wang R. , Chen X. , Mi L. , Walz T. , Springer T.A.
      Nature474:343-349(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.05 ANGSTROMS) OF 30-390 OF MUTANT SER-33;SUBUNIT;GLYCOSYLATION AT ASN-82;DISULFIDE BONDS;MUTAGENESIS OF TYR-103 AND TYR-104;ACTIVATION MECHANISM
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