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Index > Protein center > TGFB2(Gene name) > Human
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  • TGFB2 (Gene name),
  • Transforming growth factor beta-2 (Protein name ),  TGFB2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TGFB2;
    Protein name:
    Transforming growth factor beta-2(TGF-beta-2);
    Alternative:
    Cetermin;BSC-1 cell growth inhibitor;Polyergin;Glioblastoma-derived T-cell suppressor factor(G-TSF);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked. Interacts with ASPN.
    Function:
    TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    414
    Sequence:
    50:
    MHYCVLSAFL | ILHLVTVALS | LSTCSTLDMD | QFMRKRIEAI | RGQILSKLKL | 
    100:
    TSPPEDYPEP | EEVPPEVISI | YNSTRDLLQE | KASRRAAACE | RERSDEEYYA | 
    150:
    KEVYKIDMPP | FFPSENAIPP | TFYRPYFRIV | RFDVSAMEKN | ASNLVKAEFR | 
    200:
    VFRLQNPKAR | VPEQRIELYQ | ILKSKDLTSP | TQRYIDSKVV | KTRAEGEWLS | 
    250:
    FDVTDAVHEW | LHHKDRNLGF | KISLHCPCCT | FVPSNNYIIP | NKSEELEARF | 
    300:
    AGIDGTSTYT | SGDQKTIKST | RKKNSGKTPH | LLLMLLPSYR | LESQQTNRRK | 
    350:
    KRALDAAYCF | RNVQDNCCLR | PLYIDFKRDL | GWKWIHEPKG | YNANFCAGAC | 
    400:
    PYLWSSDTQH | SRVLSLYNTI | NPEASASPCC | VSQDLEPLTI | LYYIGKTPKI | 
    414:
    EQLSNMIVKS | CKCS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    KEGG:
    String:
    MIM:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human TGF-beta-2
    Cat.:
    E0218h
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    ELISA Kit for Human TGF-beta-2
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    E0218b
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    ELISA Kit for Human TGF-beta-2
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    E0218r
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    ELISA Kit for Human TGF-beta-2
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    E0218m
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    ELISA Kit for Human TGF-beta-2
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    E0218p
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    ELISA Kit for Human TGF-beta-2
    Cat.:
    E0218c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human TGF-beta-2
    Cat.:
    U0218h
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human TGF-beta-2
    Cat.:
    U0218m
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    MSDS:
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    Packing:
    96T
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    CLIA Kit for Human TGF-beta-2
    Cat.:
    U0218b
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    MSDS:
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    Packing:
    96T
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    CLIA Kit for Human TGF-beta-2
    Cat.:
    U0218p
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human TGF-beta-2
    Cat.:
    U0218c
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    Packing:
    96T
    CLIA Kit for Human TGF-beta-2
    Cat.:
    U0218r
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human TGF-beta-2
    Cat.:
    P0218Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human TGF-beta-2
    Polyclonal Antibody for Human TGF-beta-2
    Polyclonal Antibody for Human TGF-beta-2
    Polyclonal Antibody for Human TGF-beta-2
    Cat.:
    P0218Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human TGF-beta-2
    Cat.:
    P0218Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human TGF-beta-2
    Monoclonal Antibody for Human TGF-beta-2
    Monoclonal Antibody for Human TGF-beta-2
    Monoclonal Antibody for Human TGF-beta-2
    Monoclonal Antibody for Human TGF-beta-2
    Monoclonal Antibody for Human TGF-beta-2
    Protein for Human TGF-beta-2
    Protein for Human TGF-beta-2
    Protein for Human TGF-beta-2
    Protein for Human TGF-beta-2
    Protein for Human TGF-beta-2
    Protein for Human TGF-beta-2

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    References
    1. 1.
      "Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family."
      de Martin R. , Haendler B. , Hofer-Warbinek R. , Gaugitsch H. , Wrann M. , Schluesener H. , Seifert J.M. , Bodmer S. , Fontana A. , Hofer E.
      EMBO J.6:3673-3677(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A)
    2. 2.
      "Transforming growth factor-beta 2: cDNA cloning and sequence analysis."
      Madisen L. , Webb N.R. , Rose T.M. , Marquardt H. , Ikeda T. , Twardzik D.R. , Seyedin S. , Purchio A.F.
      DNA7:1-8(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM B)
    3. 3.
      "Structural and sequence analysis of TGF-beta 2 cDNA clones predicts two different precursor proteins produced by alternative mRNA splicing."
      Webb N.R. , Madisen L. , Rose T.M. , Purchio A.F.
      DNA7:493-497(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A AND B)
    4. 4.
      NIEHS SNPs program
      Submitted (2003-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS HIS-91 AND LEU-207
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM B)
      tissue: Thalamus.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    8. 8.
      "Molecular cloning and structure of the human transforming growth factor-beta 2 gene promoter."
      Noma T. , Glick A.B. , Geiser A.G. , O'Reilly M.A. , Miller J. , Roberts A.B. , Sporn M.B.
      Growth Factors4:247-255(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-115
      tissue: Lung.
    9. 9.
      "Complete amino acid sequence of human transforming growth factor type beta 2."
      Marquardt H. , Lioubin M.N. , Ikeda T.
      J. Biol. Chem.262:12127-12131(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 303-414
    10. 10.
      "Molecular characterization of a familial translocation implicates disruption of HDAC9 and possible position effect on TGFbeta2 in the pathogenesis of Peters' anomaly."
      David D. , Cardoso J. , Marques B. , Marques R. , Silva E.D. , Santos H. , Boavida M.G.
      Genomics81:489-503(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHROMOSOMAL TRANSLOCATION WITH HDAC9
    11. 11.
      "Mechanisms for asporin function and regulation in articular cartilage."
      Nakajima M. , Kizawa H. , Saitoh M. , Kou I. , Miyazono K. , Ikegawa S.
      J. Biol. Chem.282:32185-32192(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ASPN
    12. 12.
      "Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily."
      Daopin S. , Piez K.A. , Ogawa Y. , Davies D.R.
      Science257:369-373(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS)
    13. 13.
      "An unusual feature revealed by the crystal structure at 2.2-A resolution of human transforming growth factor-beta 2."
      Schlunegger M.P. , Gruetter M.G.
      Nature358:430-434(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS)
    14. 14.
      "Two novel polymorphisms in the human transforming growth factor beta 2 gene."
      Alansari A. , Hajeer A.H. , Bayat A. , Eyre S. , Carthy D. , Ollier W.E.
      Genes Immun.2:295-296(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HIS-91
    15. 15.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS LDS4 100-ALA--TYR-104 DEL; TRP-299; CYS-302 AND HIS-338
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