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Index > Protein center > TBXAS1(Gene name) > Human
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  • TBXAS1 (Gene name),
  • Thromboxane-A synthase (Protein name ),  THAS_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TBXAS1(CYP5;CYP5A1);
    Protein name:
    Thromboxane-A synthase(TXA synthase;TXS);
    Alternative:
    Cytochrome P450 5A1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    N/A
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    533
    Sequence:
    50:
    MEALGFLKLE | VNGPMVTVAL | SVALLALLKW | YSTSAFSRLE | KLGLRHPKPS | 
    100:
    PFIGNLTFFR | QGFWESQMEL | RKLYGPLCGY | YLGRRMFIVI | SEPDMIKQVL | 
    150:
    VENFSNFTNR | MASGLEFKSV | ADSVLFLRDK | RWEEVRGALM | SAFSPEKLNE | 
    200:
    MVPLISQACD | LLLAHLKRYA | ESGDAFDIQR | CYCNYTTDVV | ASVAFGTPVD | 
    250:
    SWQAPEDPFV | KHCKRFFEFC | IPRPILVLLL | SFPSIMVPLA | RILPNKNRDE | 
    300:
    LNGFFNKLIR | NVIALRDQQA | AEERRRDFLQ | MVLDARHSAS | PMGVQDFDIV | 
    350:
    RDVFSSTGCK | PNPSRQHQPS | PMARPLTVDE | IVGQAFIFLI | AGYEIITNTL | 
    400:
    SFATYLLATN | PDCQEKLLRE | VDVFKEKHMA | PEFCSLEEGL | PYLDMVIAET | 
    450:
    LRMYPPAFRF | TREAAQDCEV | LGQRIPAGAV | LEMAVGALHH | DPEHWPSPET | 
    500:
    FNPERFTAEA | RQQHRPFTYL | PFGAGPRSCL | GVRLGLLEVK | LTLLHVLHKF | 
    533:
    RFQACPETQV | PLQLESKSAL | GPKNGVYIKI | VSR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    KEGG:
    Pfam:
    String:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human TXA synthase
    MSDS:
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    ELISA Kit for Human TXA synthase
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    ELISA Kit for Human TXA synthase
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    ELISA Kit for Human TXA synthase
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    ELISA Kit for Human TXA synthase
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    E11196b
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    CLIA Kit for Human TXA synthase
    MSDS:
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    CLIA Kit for Human TXA synthase
    Cat.:
    U11196r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human TXA synthase
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    Please sign in first.
    CLIA Kit for Human TXA synthase
    Cat.:
    U11196m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human TXA synthase
    Cat.:
    U11196h
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    MSDS:
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    Packing:
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    Polyclonal Antibody for Human TXA synthase
    Cat.:
    P11196Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human TXA synthase
    Polyclonal Antibody for Human TXA synthase
    Polyclonal Antibody for Human TXA synthase
    Polyclonal Antibody for Human TXA synthase
    Monoclonal Antibody for Human TXA synthase
    Monoclonal Antibody for Human TXA synthase
    Monoclonal Antibody for Human TXA synthase
    Monoclonal Antibody for Human TXA synthase
    Monoclonal Antibody for Human TXA synthase
    Protein for Human TXA synthase
    Protein for Human TXA synthase
    Protein for Human TXA synthase
    Protein for Human TXA synthase
    Protein for Human TXA synthase

    R&D Technical Data
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    Precision
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    Linearity
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    References
    1. 1.
      "Molecular cloning of human platelet thromboxane A synthase."
      Yokoyama C. , Miyata A. , Ihara H. , Ullrich V. , Tanabe T.
      Biochem. Biophys. Res. Commun.178:1479-1484(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Platelet.
    2. 2.
      "Primary structure of human thromboxane synthase determined from the cDNA sequence."
      Ohashi K. , Ruan K.H. , Kulmacz R.J. , Wu K.K. , Wang L.-H.
      J. Biol. Chem.267:789-793(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 4)
      tissue: Lung.
    3. 3.
      "Characterization of the human gene (TBXAS1) encoding thromboxane synthase."
      Miyata A. , Yokoyama C. , Ihara H. , Bandoh S. , Takeda O. , Takahashi E. , Tanabe T.
      Eur. J. Biochem.224:273-279(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Peripheral blood.
    4. 4.
      "Human thromboxane A2 synthase."
      Shen R.-F.
      Submitted (1997-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      "Identification of genetic variants in the human thromboxane synthase gene (CYP5A1)."
      Chevalier D. , Lo-Guidice J.-M. , Sergent E. , Allorge D. , Debuysere H. , Ferrari N. , Libersa C. , Lhermitte M. , Broly F.
      Mutat. Res.432:61-67(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS HIS-60; GLU-160; SER-245; VAL-356; GLU-416; LYS-449; ASN-450 AND GLN-465
    6. 6.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Thalamus.
    7. 7.
      "The DNA sequence of human chromosome 7."
      Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
      Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Brain.
      tissue: Lung.
    10. 10.
      "Isolation of partial complementary DNA encoding human thromboxane synthase."
      Wang L.-H. , Oshashi K. , Wu K.K.
      Biochem. Biophys. Res. Commun.177:286-291(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 16-244 (ISOFORM 1/2)
      tissue: Lung.
    11. 11.
      "Immunoaffinity purification of human thromboxane synthase."
      Nuesing R. , Schneider-Voss S. , Ullrich V.
      Arch. Biochem. Biophys.280:325-330(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PRELIMINARY PROTEIN SEQUENCE OF 1-26; 96-110 AND 237-280
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE
    13. 13.
      "Amino-terminal topology of thromboxane synthase in the endoplasmic reticulum."
      Ruan K.H. , Wang L.-H. , Wu K.K. , Kulmacz R.J.
      J. Biol. Chem.268:19483-19490(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;MEMBRANE TOPOLOGY
    14. 14.
      "Severe bleeding associated with defective thromboxane synthetase."
      Mestel F. , Oetliker O. , Beck E. , Felix R. , Imbach P. , Wagner H.P.
      Lancet1:157-157(1980) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISEASE
    15. 15.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HIS-60; ILE-162; THR-331; VAL-356; GLU-416 AND THR-429
    16. 16.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
    17. 17.
      "Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis."
      Halushka M.K. , Fan J.-B. , Bentley K. , Hsie L. , Shen N. , Weder A. , Cooper R. , Lipshutz R. , Chakravarti A.
      Nat. Genet.22:239-247(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS GLU-160; VAL-356; GLU-416; CYS-424 AND THR-429
    18. 18.
      "Catalog of 680 variations among eight cytochrome p450 (CYP) genes, nine esterase genes, and two other genes in the Japanese population."
      Saito S. , Iida A. , Sekine A. , Kawauchi S. , Higuchi S. , Ogawa C. , Nakamura Y.
      J. Hum. Genet.48:249-270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ILE-124; LYS-388; LYS-449 AND GLN-501
    19. 19.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] TRP-85
    20. 20.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS GHDD PRO-82; GLN-412; TRP-481 AND PRO-487
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