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Index > Protein center > Timm13(Gene name) > Mouse
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  • Timm13 (Gene name),
  • Mitochondrial import inner membrane translocase subunit Tim13 (Protein name ),  TIM13_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Timm13(Tim13a;Timm13a);
    Protein name:
    Mitochondrial import inner membrane translocase subunit Tim13;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Heterohexamer; composed of 3 copies of TIMM8 (TIMM8A or TIMM8B) and 3 copies of TIMM13, named soluble 70 kDa complex. Associates with the TIM22 complex, whose core is composed of TIMM22.
    Function:
    Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins.
    Subcellular Location:
    Mitochondrion inner membrane Peripheral membrane protein Intermembrane side
    Protein Attributes:
    Sequence length:
    95
    Sequence:
    50:
    MDSGFGSDFG | GTGGGKLDPG | AIMEQVKVQI | AVANAQELLQ | RMTDKCFRKC | 
    95:
    IGKPGGSLDN | SEQKCIAMCM | DRYMDAWNTV | SRAYNSRLQR | ERANM
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    String:
    Pfam:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Mitochondrial import inner membrane translocase subunit Tim13
    ELISA Kit for Mouse Mitochondrial import inner membrane translocase subunit Tim13
    ELISA Kit for Mouse Mitochondrial import inner membrane translocase subunit Tim13
    CLIA Kit for Mouse Mitochondrial import inner membrane translocase subunit Tim13
    CLIA Kit for Mouse Mitochondrial import inner membrane translocase subunit Tim13
    CLIA Kit for Mouse Mitochondrial import inner membrane translocase subunit Tim13
    Polyclonal Antibody for Mouse Mitochondrial import inner membrane translocase subunit Tim13
    Polyclonal Antibody for Mouse Mitochondrial import inner membrane translocase subunit Tim13
    Polyclonal Antibody for Mouse Mitochondrial import inner membrane translocase subunit Tim13
    Monoclonal Antibody for Mouse Mitochondrial import inner membrane translocase subunit Tim13
    Monoclonal Antibody for Mouse Mitochondrial import inner membrane translocase subunit Tim13
    Monoclonal Antibody for Mouse Mitochondrial import inner membrane translocase subunit Tim13
    Protein for Mouse Mitochondrial import inner membrane translocase subunit Tim13
    Protein for Mouse Mitochondrial import inner membrane translocase subunit Tim13
    Protein for Mouse Mitochondrial import inner membrane translocase subunit Tim13

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    Linearity
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    References
    1. 1.
      "The mitochondrial TIM22 preprotein translocase is highly conserved throughout the eukaryotic kingdom."
      Bauer M.F. , Rothbauer U. , Muehlenbein N. , Smith R.J.H. , Gerbitz K.-D. , Neupert W. , Brunner M. , Hofmann S.
      FEBS Lett.464:41-47(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      strain: NOD.
      tissue: Brain.
      tissue: Thymus.
      tissue: Tongue.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Mammary tumor.
    4. 4.
      Lubec G. , Kang S.U.
      Submitted (2007-04) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 28-41 AND 50-64;IDENTIFICATION BY MASS SPECTROMETRY
      strain: C57BL/6.
      tissue: Brain.
    5. 5.
      "The calcium-binding aspartate/glutamate carriers, citrin and aralar1, are new substrates for the DDP1/TIMM8a-TIMM13 complex."
      Roesch K. , Hynds P.J. , Varga R. , Tranebjaerg L. , Koehler C.M.
      Hum. Mol. Genet.13:2101-2111(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    6. 6.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-53;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
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