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Index > Protein center > TIMP1(Gene name) > Human
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  • TIMP1 (Gene name),
  • Metalloproteinase inhibitor 1 (Protein name ),  TIMP1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    TIMP1(CLGI;TIMP);
    Protein name:
    Metalloproteinase inhibitor 1;
    Alternative:
    Fibroblast collagenase inhibitor(Collagenase inhibitor);Erythroid-potentiating activity(EPA);Tissue inhibitor of metalloproteinases 1(TIMP-1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. Does not act on MMP-14.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    207
    Sequence:
    50:
    MAPFEPLASG | ILLLLWLIAP | SRACTCVPPH | PQTAFCNSDL | VIRAKFVGTP | 
    100:
    EVNQTTLYQR | YEIKMTKMYK | GFQALGDAAD | IRFVYTPAME | SVCGYFHRSH | 
    150:
    NRSEEFLIAG | KLQDGLLHIT | TCSFVAPWNS | LSLAQRRGFT | KTYTVGCEEC | 
    200:
    TVFPCLSIPC | KLQSGTHCLW | TDQLLQGSEK | GFQSRHLACL | PREPGLCTWQ | 
    207:
    SLRSQIA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    SMR:
    KEGG:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Metalloproteinase inhibitor 1
    Cat.:
    E0552m
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Metalloproteinase inhibitor 1
    Cat.:
    E0552r
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Metalloproteinase inhibitor 1
    MSDS:
    Please sign in first.
    ELISA Kit for Human Metalloproteinase inhibitor 1
    Cat.:
    E0552p
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Metalloproteinase inhibitor 1
    Cat.:
    E0552b
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Metalloproteinase inhibitor 1
    Cat.:
    E0552d
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Metalloproteinase inhibitor 1
    Cat.:
    E0552h
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human Metalloproteinase inhibitor 1
    Cat.:
    U0552r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Metalloproteinase inhibitor 1
    MSDS:
    Please sign in first.
    CLIA Kit for Human Metalloproteinase inhibitor 1
    Cat.:
    U0552d
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Metalloproteinase inhibitor 1
    Cat.:
    U0552p
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Metalloproteinase inhibitor 1
    Cat.:
    U0552h
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Metalloproteinase inhibitor 1
    Cat.:
    U0552b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Metalloproteinase inhibitor 1
    Cat.:
    U0552m
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Metalloproteinase inhibitor 1
    Cat.:
    P0552Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Metalloproteinase inhibitor 1
    Polyclonal Antibody for Human Metalloproteinase inhibitor 1
    Cat.:
    P0552Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Metalloproteinase inhibitor 1
    Polyclonal Antibody for Human Metalloproteinase inhibitor 1
    Polyclonal Antibody for Human Metalloproteinase inhibitor 1
    Polyclonal Antibody for Human Metalloproteinase inhibitor 1
    Cat.:
    P0552Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Metalloproteinase inhibitor 1
    Monoclonal Antibody for Human Metalloproteinase inhibitor 1
    Monoclonal Antibody for Human Metalloproteinase inhibitor 1
    Monoclonal Antibody for Human Metalloproteinase inhibitor 1
    Monoclonal Antibody for Human Metalloproteinase inhibitor 1
    Monoclonal Antibody for Human Metalloproteinase inhibitor 1
    Monoclonal Antibody for Human Metalloproteinase inhibitor 1
    Protein for Human Metalloproteinase inhibitor 1
    Protein for Human Metalloproteinase inhibitor 1
    Protein for Human Metalloproteinase inhibitor 1
    Protein for Human Metalloproteinase inhibitor 1
    Protein for Human Metalloproteinase inhibitor 1
    Protein for Human Metalloproteinase inhibitor 1
    Cat.:
    R0552h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Human Metalloproteinase inhibitor 1
    Cat.:
    R0552m
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%

    R&D Technical Data
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              12% SDS-PAGE Analysis

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    Precision
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    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤ 5.8%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤ 8.9%

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    Recovery
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    Recovery was determined by spiking various levels of ACE into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    99

    92-105

    Plasma

    98

    91-106

     

     

     

     

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    Linearity
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    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    90-103%

    91-104%

    94-102%

    92-105%

    EDTA plasma(n=5)

    91-97%

    93-102%

    89-105%

    91-106%

    heparin plasma(n=5)

    92-104%

     

    94-108%

    95-109%

    91-107%

     

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    References
    1. 1.
      "Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity."
      Docherty A.J.P. , Lyons A. , Smith B.J. , Wright E.M. , Stephens P.E. , Harris T.J.R. , Murphy G. , Reynolds J.J.
      Nature318:66-69(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 24-51;FUNCTION;SUBCELLULAR LOCATION;GLYCOSYLATION
    2. 2.
      "Molecular characterization and expression of the gene encoding human erythroid-potentiating activity."
      Gasson J.C. , Golde D.W. , Kaufman S.E. , Westbrook C.A. , Hewick R.M. , Kaufman R.J. , Wong G.G. , Temple P.A. , Leary A.C. , Brown E.L. , Orr E.C. , Clark S.C.
      Nature315:768-771(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 24-49;SUBCELLULAR LOCATION;GLYCOSYLATION;FUNCTION
    3. 3.
      "Primary structure and cDNA cloning of human fibroblast collagenase inhibitor."
      Carmichael D.F. , Sommer A. , Thompson R.C. , Anderson D.C. , Smith C.G. , Welgus H.G. , Stricklin G.P.
      Proc. Natl. Acad. Sci. U.S.A.83:2407-2411(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 24-207;DISULFIDE BOND;SUBCELLULAR LOCATION;GLYCOSYLATION
    4. 4.
      "Molecular cloning and synthesis of biologically active human tissue inhibitor of metalloproteinases in yeast."
      Kaczorek M. , Honore N. , Ribes V. , Dehoux P. , Cornet P. , Cartwright T. , Streeck R.E.
      Biotechnology (N.Y.)5:595-598(1987)
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    5. 5.
      "Characterization of three abundant mRNAs from human ovarian granulosa cells."
      Rapp G. , Freudenstein J. , Klaudiny J. , Mucha J. , Wempe F. , Zimmer M. , Scheit K.H.
      DNA Cell Biol.9:479-485(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Ovary.
    6. 6.
      "Characterization of a human corneal metalloproteinase inhibitor (TIMP-1)."
      Opbroek A. , Kenney M.C. , Brown D.
      Curr. Eye Res.12:877-883(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Cervix.
    8. 8.
      "Genomic organization of the human TIMP-1 gene. Investigation of a causative role in the pathogenesis of X-linked retinitis pigmentosa 2."
      Hardcastle A.J. , Thiselton D.L. , Nayudu M. , Hampson R.M. , Bhattacharya S.S.
      Invest. Ophthalmol. Vis. Sci.38:1893-1896(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-40
    9. 9.
      "Isolation and characterization of tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2) from human rheumatoid synovial fluid."
      Osthues A. , Knaueper V. , Oberhoff R. , Reinke H. , Tschesche H.
      FEBS Lett.296:16-20(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 24-38;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;FUNCTION
      tissue: Synovial fluid.
    10. 10.
      "The cytokine-protease connection: identification of a 96-kD THP-1 gelatinase and regulation by interleukin-1 and cytokine inducers."
      van Ranst M. , Norga K. , Masure S. , Proost P. , Vandekerckhove F. , Auwerx J. , van Damme J. , Opdenakker G.
      Cytokine3:231-239(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 24-52
    11. 11.
      "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
      Zhang Z. , Henzel W.J.
      Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 24-38
    12. 12.
      Matsuda T. , Kohno K. , Kuwano M.
      Submitted (1992-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 42-207
    13. 13.
      "Disulphide bond assignment in human tissue inhibitor of metalloproteinases (TIMP)."
      Williamson R.A. , Martson F.A.O. , Angal S. , Koklitis P. , Panico M. , Morris H.R. , Carne A.F. , Smith B.J. , Harris T.J.R. , Freedman R.B.
      Biochem. J.268:267-274(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BONDS;PARTIAL PROTEIN SEQUENCE
    14. 14.
      "Site-directed mutations that alter the inhibitory activity of the tissue inhibitor of metalloproteinases-1: importance of the N-terminal region between cysteine 3 and cysteine 13."
      O'Shea M. , Willenbrock F. , Williamson R.A. , Cockett M.I. , Freedman R.B. , Reynolds J.J. , Docherty A.J.P. , Murphy G.
      Biochemistry31:10146-10152(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS;FUNCTION
    15. 15.
      "Metalloproteinase inhibition and erythroid potentiation are independent activities of tissue inhibitor of metalloproteinases-1."
      Chesler L. , Golde D.W. , Bersch N. , Johnson M.D.
      Blood86:4506-4515(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS A GROWTH FACTOR AND PROTEASE INHIBITOR;INTERACTION WITH MMP3;SUBCELLULAR LOCATION;MUTAGENESIS OF HIS-30 AND GLN-32
    16. 16.
      "Biochemical characterization of human collagenase-3."
      Knaeuper V. , Lopez-Otin C. , Smith B. , Knight G. , Murphy G.
      J. Biol. Chem.271:1544-1550(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MMP13;FUNCTION
    17. 17.
      "The role of the C-terminal domain of human collagenase-3 (MMP-13) in the activation of procollagenase-3, substrate specificity, and tissue inhibitor of metalloproteinase interaction."
      Knaeuper V. , Cowell S. , Smith B. , Lopez-Otin C. , O'Shea M. , Morris H. , Zardi L. , Murphy G.
      J. Biol. Chem.272:7608-7616(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MMP13;FUNCTION
    18. 18.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-53
      tissue: Plasma.
    19. 19.
      "Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein."
      Jung K.K. , Liu X.W. , Chirco R. , Fridman R. , Kim H.R.
      EMBO J.25:3934-3942(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CD63
    20. 20.
      "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry."
      Ramachandran P. , Boontheung P. , Xie Y. , Sondej M. , Wong D.T. , Loo J.A.
      J. Proteome Res.5:1493-1503(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-53 AND ASN-101
      tissue: Saliva.
    21. 21.
      "Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach."
      Lewandrowski U. , Moebius J. , Walter U. , Sickmann A.
      Mol. Cell. Proteomics5:226-233(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-53
      tissue: Platelet.
    22. 22.
      "A strategy for precise and large scale identification of core fucosylated glycoproteins."
      Jia W. , Lu Z. , Fu Y. , Wang H.P. , Wang L.H. , Chi H. , Yuan Z.F. , Zheng Z.B. , Song L.N. , Han H.H. , Liang Y.M. , Wang J.L. , Cai Y. , Zhang Y.K. , Deng Y.L. , Ying W.T. , He S.M. , Qian X.H.
      Mol. Cell. Proteomics8:913-923(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-53
    23. 23.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    24. 24.
      "Timp1 interacts with beta-1 integrin and CD63 along melanoma genesis and confers anoikis resistance by activating PI3-K signaling pathway independently of Akt phosphorylation."
      Toricelli M. , Melo F.H. , Peres G.B. , Silva D.C. , Jasiulionis M.G.
      Mol. Cancer12:22-22(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH CD63 AND ITGB1
    25. 25.
      "TIMP-1 modulates chemotaxis of human neural stem cells through CD63 and integrin signalling."
      Lee S.Y. , Kim J.M. , Cho S.Y. , Kim H.S. , Shin H.S. , Jeon J.Y. , Kausar R. , Jeong S.Y. , Lee Y.S. , Lee M.A.
      Biochem. J.459:565-576(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
    26. 26.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    27. 27.
      "Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1."
      Gomis-Rueth F.-X. , Maskos K. , Betz M. , Bergner A. , Huber R. , Suzuki K. , Yoshida N. , Nagase H. , Brew K. , Bourenkov G.P. , Bartunik H. , Bode W.
      Nature389:77-81(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS) OF 24-207 IN COMPLEX WITH MMP3;INTERACTION WITH MMP3
    28. 28.
      "NMR structure of tissue inhibitor of metalloproteinases-1 implicates localized induced fit in recognition of matrix metalloproteinases."
      Wu B. , Arumugam S. , Gao G. , Lee G.I. , Semenchenko V. , Huang W. , Brew K. , Van Doren S.R.
      J. Mol. Biol.295:257-268(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 24-149;DISULFIDE BOND
    29. 29.
      "Global orientation of bound MMP-3 and N-TIMP-1 in solution via residual dipolar couplings."
      Arumugam S. , Van Doren S.R.
      Biochemistry42:7950-7958(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 24-149 IN COMPLEX WITH MMP3;INTERACTION WITH MMP3
    30. 30.
      "Crystal structure of the catalytic domain of matrix metalloproteinase-1 in complex with the inhibitory domain of tissue inhibitor of metalloproteinase-1."
      Iyer S. , Wei S. , Brew K. , Acharya K.R.
      J. Biol. Chem.282:364-371(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.54 ANGSTROMS) OF 24-149 IN COMPLEX WITH MMP1;FUNCTION;INTERACTION WITH MMP1 AND MMP3;DISULFIDE BOND;MUTAGENESIS OF THR-25
    31. 31.
      "The intrinsic protein flexibility of endogenous protease inhibitor TIMP-1 controls its binding interface and affects its function."
      Grossman M. , Tworowski D. , Dym O. , Lee M.H. , Levy Y. , Murphy G. , Sagi I.
      Biochemistry49:6184-6192(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.05 ANGSTROMS) OF 24-148 OF MUTANT LEU-121 IN COMPLEX WITH MMP14;FUNCTION;INTERACTION WITH MMP14;DISULFIDE BOND;MUTAGENESIS OF THR-121
    32. 32.
      "Matrix metalloproteinase-10 (MMP10) interaction with tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2: binding studies and crystal structure."
      Batra J. , Robinson J. , Soares A.S. , Fields A.P. , Radisky D.C. , Radisky E.S.
      J. Biol. Chem.287:15935-15946(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 24-207 IN COMPLEX WITH MMP10;FUNCTION;INTERACTION WITH MMP10;DISULFIDE BOND
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