Tlr7 ELISA Kit for Mouse(Mus musculus) | EIAab.comTlr7 ELISA Kit for Mouse(Mus musculus)

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Tlr7 (Gene name),

Toll-like receptor 7 (Protein name ), TLR7_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Tlr7;

Protein name:

Toll-like receptor 7;

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with MYD88 via their respective TIR domains (By similarity). Interacts with UNC93B1.

Function:

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

Subcellular Location:

Endoplasmic reticulum membrane Single-pass type I membrane protein Endosome Lysosome Cytoplasmic vesicle phagosome Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.

Protein Attributes:

Sequence length:

1050

Sequence:

50:

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950:

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1050:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P58681

UniGene:

Mm.23979

SMR:

P58681

KEGG:

mmu:170743

Pfam:

PF00560

Uniprot:

P58681

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ELISA Kit for Mouse Toll-like receptor 7

Cat.:

E1950h

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Packing:

96T

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ELISA Kit for Mouse Toll-like receptor 7

Cat.:

E1950m

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Manual:

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MSDS:

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Packing:

96T

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CLIA Kit for Mouse Toll-like receptor 7

Cat.:

U1950h

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Toll-like receptor 7

Cat.:

U1950m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Toll-like receptor 7

Cat.:

P1950Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Toll-like receptor 7

Cat.:

P1950Rb-m

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Toll-like receptor 7

Protein for Mouse Toll-like receptor 7

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Molecular cloning of murine Toll-like receptor 7."
Heil F.J. , Lipford G.B. , Wagner H. , Bauer S.M.
Submitted (2001-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Macrophage.
2.

"Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA."
Diebold S.S. , Kaisho T. , Hemmi H. , Akira S. , Reis e Sousa C.
Science303:1529-1531(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
3.

"The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling."
Brinkmann M.M. , Spooner E. , Hoebe K. , Beutler B. , Ploegh H.L. , Kim Y.M.
J. Cell Biol.177:265-275(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;INTERACTION WITH UNC93B1
4.

"UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes."
Kim Y.M. , Brinkmann M.M. , Paquet M.E. , Ploegh H.L.
Nature452:234-238(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION

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