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Index > Protein center > Tnfsf11(Gene name) > Rat
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  • Tnfsf11 (Gene name),
  • Tumor necrosis factor ligand superfamily member 11 (Protein name ),  TNF11_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Tnfsf11(Opgl;Rankl;Trance);
    Protein name:
    Tumor necrosis factor ligand superfamily member 11;
    Alternative:
    Osteoprotegerin ligand(OPGL);Osteoclast differentiation factor(ODF);TNF-related activation-induced cytokine(TRANCE);Receptor activator of nuclear factor kappa-B ligand(RANKL);
    CD:
    CD254;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homotrimer.
    Function:
    Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.
    Subcellular Location:
    Tumor necrosis factor ligand superfamily member 11, soluble form Secreted
    Protein Attributes:
    Sequence length:
    318
    Sequence:
    50:
    MRRANRDYGK | YLRGSEEMGS | CPGVPHEGPL | HPAPSAPAPA | PPPAASRFMF | 
    100:
    LALLGLGLGQ | VVCSIALFLY | FRAQMDPNRI | SEDSTRCFYR | ILRLRENTGL | 
    150:
    QDSTLESEDT | EALPDSCRRM | KQAFQGAVQR | ELQHIVGPQR | FSGVPAMMEG | 
    200:
    SWLDVARRGK | PEAQPFAHLT | INAADIPSGS | HKVSLSSWYH | DRGWAKISNM | 
    250:
    TLSNGKLRVN | QDGFYYLYAN | ICFRHHETSG | SVPADYLQLM | VYVVKTSIKI | 
    300:
    PSSHNLMKGG | STKNWSGNSE | FHFYSINVGG | FFKLRAGEEI | SVQVSNPSLL | 
    318:
    DPDQDATYFG | AFKVQDID
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    Pfam:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Tumor necrosis factor ligand superfamily member 11
    Cat.:
    E0855r
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    96T
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    ELISA Kit for Rat Tumor necrosis factor ligand superfamily member 11
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    E0855m
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    ELISA Kit for Rat Tumor necrosis factor ligand superfamily member 11
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    E0855h
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    CLIA Kit for Rat Tumor necrosis factor ligand superfamily member 11
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    U0855h
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Tumor necrosis factor ligand superfamily member 11
    Cat.:
    U0855m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Tumor necrosis factor ligand superfamily member 11
    Cat.:
    U0855r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 11
    Cat.:
    P0855Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 11
    Cat.:
    P0855Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 11
    Cat.:
    P0855Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 11
    Monoclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 11
    Monoclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 11
    Protein for Rat Tumor necrosis factor ligand superfamily member 11
    Protein for Rat Tumor necrosis factor ligand superfamily member 11
    Protein for Rat Tumor necrosis factor ligand superfamily member 11

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    Precision
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    Linearity
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    References
    1. 1.
      "Cloning, sequence and functional characterization of the rat homologue of receptor activator of NF-kB ligand."
      Xu J.K. , Tan J.K. , Huang L. , Gao X.H. , Laird R. , Liu D. , Wysocki S. , Zheng M.H.
      J. Bone Miner. Res.15:2178-2186(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Tibial bone.
    2. 2.
      "Evidence that the rat osteopetrotic mutation toothless (tl) is not in the TNFSF11 (TRANCE, RANKL, ODF, OPGL) gene."
      Odgren P.R. , Kim N. , van Wesenbeeck L. , MacKay C. , Mason-Savas A. , Safadi F.F. , Popoff S.N. , Lengner C. , van-Hul W. , Choi Y. , Marks S.C. Jr.
      Int. J. Dev. Biol.45:853-859(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 266-318
      strain: Fischer 344.
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