Protein name:
Serotransferrin (Transferrin) ;
Alternative:
Siderophilin ;Beta-1 metal-binding globulin ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
Subcellular Location:
Secreted
Protein Attributes:
50:
MRLAVGALLV | CAVLGLCLAV | PDKTVRWCAV | SEHEATKCQS | FRDHMKSVIP |
100:
SDGPSVACVK | KASYLDCIRA | IAANEADAVT | LDAGLVYDAY | LAPNNLKPVV |
150:
AEFYGSKEDP | QTFYYAVAVV | KKDSGFQMNQ | LRGKKSCHTG | LGRSAGWNIP |
200:
IGLLYCDLPE | PRKPLEKAVA | NFFSGSCAPC | ADGTDFPQLC | QLCPGCGCST |
250:
LNQYFGYSGA | FKCLKDGAGD | VAFVKHSTIF | ENLANKADRD | QYELLCLDNT |
300:
RKPVDEYKDC | HLAQVPSHTV | VARSMGGKED | LIWELLNQAQ | EHFGKDKSKE |
350:
FQLFSSPHGK | DLLFKDSAHG | FLKVPPRMDA | KMYLGYEYVT | AIRNLREGTC |
400:
PEAPTDECKP | VKWCALSHHE | RLKCDEWSVN | SVGKIECVSA | ETTEDCIAKI |
450:
MNGEADAMSL | DGGFVYIAGK | CGLVPVLAEN | YNKSDNCEDT | PEAGYFAIAV |
500:
VKKSASDLTW | DNLKGKKSCH | TAVGRTAGWN | IPMGLLYNKI | NHCRFDEFFS |
550:
EGCAPGSKKD | SSLCKLCMGS | GLNLCEPNNK | EGYYGYTGAF | RCLVEKGDVA |
600:
FVKHQTVPQN | TGGKNPDPWA | KNLNEKDYEL | LCLDGTRKPV | EEYANCHLAR |
650:
APNHAVVTRK | DKEACVHKIL | RQQQHLFGSN | VTDCSGNFCL | FRSETKDLLF |
698:
RDDTVCLAKL | HDRNTYEKYL | GEEYVKAVGN | LRKCSTSSLL | EACTFRRP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rabbit
Human
Bovine
Pig
Mouse
Rat
ELISA Kit for Human Transferrin
ELISA Kit for Human Transferrin
ELISA Kit for Human Transferrin
ELISA Kit for Human Transferrin
ELISA Kit for Human Transferrin
ELISA Kit for Human Transferrin
CLIA Kit for Human Transferrin
CLIA Kit for Human Transferrin
CLIA Kit for Human Transferrin
CLIA Kit for Human Transferrin
CLIA Kit for Human Transferrin
CLIA Kit for Human Transferrin
Polyclonal Antibody for Human Transferrin
Polyclonal Antibody for Human Transferrin
Polyclonal Antibody for Human Transferrin
Polyclonal Antibody for Human Transferrin
Polyclonal Antibody for Human Transferrin
Polyclonal Antibody for Human Transferrin
Monoclonal Antibody for Human Transferrin
Monoclonal Antibody for Human Transferrin
Monoclonal Antibody for Human Transferrin
Monoclonal Antibody for Human Transferrin
Monoclonal Antibody for Human Transferrin
Monoclonal Antibody for Human Transferrin
Protein for Human Transferrin
Protein for Human Transferrin
Protein for Human Transferrin
Protein for Human Transferrin
Protein for Human Transferrin
Protein for Human Transferrin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];VARIANTS TF*B2; TF*CHI; TF*D1 AND VAL-448
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];VARIANT VAL-448
tissue :
Liver .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS VAL-448 AND ATRAF PRO-477
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ARG-55; SER-277; GLY-296; VAL-448 AND SER-589
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT VAL-448
7.
"The DNA sequence, annotation and analysis of human chromosome 3."
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Nature440:1194-1198(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.
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Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT VAL-448
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT VAL-448
tissue :
Brain .
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-72 AND 291-300
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-14
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 20-698;VARIANT VAL-448
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 45-72
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 73-698;VARIANT VAL-448
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 99-698;VARIANT VAL-448
tissue :
Fetal liver .
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 108-121; 259-273; 332-343; 374-384; 434-452; 454-464; 495-508; 531-541; 577-600 AND 684-696;IDENTIFICATION BY MASS SPECTROMETRY;VARIANT VAL-448
tissue :
Brain .
tissue :
Cajal-Retzius cell .
tissue :
Fetal brain cortex .
17.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 263-266; 454-458; 531-538 AND 589-595
tissue :
Heart .
18.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 422-698;VARIANT VAL-448
19.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 564-624;VARIANTS TF*C2 AND SER-589
tissue :
Brain .
20.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 564-624
21.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 636-696
22.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISULFIDE BONDS
23.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : MUTAGENESIS
24.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-432 AND ASN-630
tissue :
Bile .
25.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-432 AND ASN-630
tissue :
Plasma .
26.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION AT ASN-432; ASN-491 AND ASN-630
27.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-432 AND ASN-630
tissue :
Plasma .
28.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-630
tissue :
Saliva .
29.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-432 AND ASN-630
tissue :
Liver .
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[
PubMed ]
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Europe PMC ]
[
Abstract ]
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Cited for : GLYCOSYLATION AT ASN-630
31.
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Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-432 AND ASN-630;STRUCTURE OF CARBOHYDRATES
tissue :
Cerebrospinal fluid .
32.
"Two high-resolution crystal structures of the recombinant N-lobe of human transferrin reveal a structural change implicated in iron release."
Macgillivray R.T.A.
,
Moore S.A.
,
Chen J.
,
Anderson B.F.
,
Baker H.
,
Luo Y.
,
Bewley M.C.
,
Smith C.A.
,
Murphy M.E.P.
,
Wang Y.
,
Mason A.B.
,
Woodworth R.C.
,
Brayer G.D.
,
Baker E.N.
Biochemistry37:7919-7928(1998)
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PubMed ]
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Europe PMC ]
[
Abstract ]
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Cited for : X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS) OF 22-350
33.
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Cited for : X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 22-350
34.
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Cited for : X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 23-352
35.
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Cited for : VARIANT SER-142
36.
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Cited for : VARIANT GLU-646
37.
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Cited for : VARIANTS SER-277; SER-589 AND GLU-671;CHARACTERIZATION OF VARIANT SER-277
38.
"Identification of 96 single nucleotide polymorphisms in eight genes involved in iron metabolism: efficiency of bioinformatic extraction compared with a systematic sequencing approach."
Douabin-Gicquel V.
,
Soriano N.
,
Ferran H.
,
Wojcik F.
,
Palierne E.
,
Tamim S.
,
Jovelin T.
,
McKie A.T.
,
Le Gall J.-Y.
,
David V.
,
Mosser J.
Hum. Genet.109:393-401(2001)
[
PubMed ]
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Europe PMC ]
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Abstract ]
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Cited for : VARIANTS SER-277 AND SER-589
39.
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Cited for : VARIANT ATRAF ASN-77
40.
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Cited for : VARIANT [LARGE SCALE ANALYSIS] VAL-448;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]